A
PROFILE
UPM's Staff Profile
DR. YU CHOO YEE
PEGAWAI PENYELIDIK
INSTITUTE OF BIOSCIENCE
yu.choo
BM
EN

PROFESSIONAL

yu.choo@upm.edu.my
NAME :
(Dr.) Yu Choo Yee
POSITION :
Pegawai Penyelidik
ENTITY :
Institute Of Bioscience

CONFERENCE / WORKSHOP / SEMINAR
2023
Yu, C.Y. (2023) Next-generation sequencing for Avian Research: Opportunities and Challenges. In: 1st International Conference on Poultry and Fish Vaccinology and Diagnosis, 17-18 January 2023, The Everly Hotel Putrajaya.
2023
Yu, C.Y. (2023) Artificial Intelligence for Smartphone-based Point-of-care Diagnostics. In: Perdana University Conference 2023, 8-9 September 2023, Perdana University.
2016
Yu, C. Y., G. Y. Ang, L. K. Teh & M. Z. Salleh (2016). Sports genomics. In: Pharma+BioAsia Conference, 28-29 September 2016, Kuala Lumpur Convention Centre, Malaysia.
2016
Ang, G. Y., C. Y. Yu, L. K. Teh & M. Z. Salleh (2016). Detection of cytochrome P450 genetic polymorphisms with next-generation sequencing platform. In: Pharma+BioAsia Conference, 28-29 September 2016, Kuala Lumpur Convention Centre, Malaysia.
2013
Yu, C. Y., G. Y. Ang & Y. Y. Chan (2013). An integrated electrochemical genosensing platform based on dry reagent multiplex LATE-PCR strategy. In: AsiaSense: The 6th International Conference on Sensors, 27-29 August 2013, Ramada Plaza Melaka, Melaka, Malaysia.
2013
Yu, C. Y., G. Y. Ang & Y. Y. Chan (2013). Development of a multiplex LATE-PCR-coupled electrochemical genosensor platform for cholera. In: National Biotechnology Seminar (NBS), 6-8 June 2013, Hotel Equatorial, Penang, Malaysia.
2013
Yu, C. Y., G. Y. Ang & Y. Y. Chan (2013). A multiplex electrochemical genosensor for cholera using disposable screen-printed gold electrode bisensors. In: 3rd International Conference on Bio-sensing Technology, 13-15 May 2013, Hotel Melia, Sitges, Spain.
2013
Ang, G. Y., C. Y. Yu & Y. Y. Chan (2013). A dual-acting PCR stabilizer-hybridization accelerator formulation for hybridization-based nucleic acid lateral flow detection platform. In: 3rd International Conference on Bio-sensing Technology, 13-15 May 2013, Hotel Melia, Sitges, Spain.
2012
Hamzah, I. H., C. Y. Yu, S. Korakkottil Kunhi Mohd, A. Abd Manaf, O. Sidek & Y. Y. Chan (2012). Fabrication and characterization of poly(dimethyl)siloxane (PDMS)-flame retardant 4 (FR4) label free DNA sensor. In: International Conference on Agricultural, Biotechnology, Biological and Biosystems Engineering (ICABBBE), 15-17 January 2012, Geroldswil
2011
Yu, C. Y. & C. Y. Yean (2011). A multiplex linear-after-the-exponential-PCR for toxigenic Vibrio cholerae sergroups O1 and O139. In: 2nd Symposium of USM Fellowship, 23-24 November 2011, Vistana Hotel, Penang, Malaysia.
2011
Yu, C. Y., G. Y. Ang & Y. Y. Chan (2011). A novel CTX prophage array in Kelantan cholera outbreak strain. In: 4th Regional Conference on Molecular Medicine (RCMM), 9-11 October 2011, G-Hotel, Penang, Malaysia.
2011
Yu, C. Y., G. Y. Ang & Y. Y. Chan (2011). Cholera outbreak caused by Vibrio cholerae O1 with atypical El Tor biotype in Terengganu, Malaysia. In: 16th National Conference on Medical and Health Sciences (NCMHS), 22-23 June 2011, Health Campus, Universiti Sains Malaysia, Malaysia.
2011
Nawi, M. A. M., C. Y. Yu, G. Y. Ang, G. C. Tan, A. Acosta, M. E. Sarmiento, G. Falero, I. Rodrigue, O. Otero, F. Reyes, F. Camacho, C. Y. Yean & N. M. Nor (2011). A study on 16-kDa antigen as a potential biomarker for the detection of Mycobacterium tuberculosis. In: 16th National Conference on Medical and Health Sciences (NCMHS), 22-23 June 2011, H
2010
Hamzah, I. H., C. Y. Yu, A. Abd Manaf, O. Sidek & Y. Y. Chan (2010). Performance characteristic study of fabricated Au/Ti sensor by using ferricyanide redox reaction for DNA hybridization detection. In: 1st AMDI International Biohealth Science Conference (IBSC), 29 November 2010-1 December 2010, Bayview Beach Resort, Penang, Malaysia.
2010
Yu, C. Y., G. Y. Ang, A. L. Chua, H. T. Elina, S. Y. Lee, G. Falero, O. Otero, I. Rodriguez, F. Reyes, A. Acosta, M. E. Sarmiento, Y. Y. Chan, P. Lalitha & M. Ravichandran (2010). Direct immunochromatography assay for simultaneous identification of Vibrio cholerae serogroups O1 and O139. In: 14th International Conference on Emerging Infectious Dise
2010
Ang, G. Y., C. Y. Yu, G. C. Tan, B. Kamarudin, E. H. Tan & Y. Y. Chan (2010). Molecular analysis of Vibrio cholerae isolates from a bi-state cholera outbreak in the east coast of Malaysia. In: 2nd National Conference on Environment and Health (NCEH), 17-18 March 2010, Renaissance Hotel, Kota Bharu, Kelantan, Malaysia.
AWARD AND ACHIEVEMENT
2018
R. M. J. James, N. R. Rosli, C. Y. Yu, L. K. Teh, Z. Salleh & R. Janor (2018). Genosuccess – A genotyping kit to identify dominator of success. Gold Award In: Invention, Innovation & Design Exposition (iidex), 24-28 September 2018, UiTM, Shah Alam.
2018
M. Z. Salleh, L. Y., Teh, C. Y. Yu, G. Y., Ang & M. N. F. Norizhab (2018). ExerNutrix – A sports genomics & nutrigenomics genotyping kit. Silver Award In: 29th International Invention, Innovations & Technology Exhibition (ITEX), 10-12 May 2018, Kuala Lumpur Convention Centre (KLCC), Kuala Lumpur.
2018
M. Z. Salleh, L. Y., Teh, G. Y., Ang, C. Y. Yu & M. N. F. Norizhab (2018). RT-GeType: Real-time genotyping kit for HLA-B*15:02. Japan Intellectual Property Association Award (JIPA) and Silver Award In: 17th Malaysia Technology Expo (MTE), 22-24 February 2018, Putra World Trade Centre (PWTC), Kuala Lumpur.
2017
M. Z. Salleh, L. Y., Teh, G. Y., Ang, C. Y. Yu & M. N. F. Norizhab (2017). RT-GeType: Real-time genotyping kit for HLA-B*15:02. Gold Award In: The International Conference and exposition on Inventions by Institutions of Higher Learning (PECIPTA), 7-9 October 2017, Gong Badak, Terengganu.
2017
M. Z. Salleh, L. Y., Teh, G. Y., Ang, C. Y. Yu & M. N. F. Norizhab (2017). RT-GeType: Real-time genotyping kit for HLA-B*15:02. Grand Award, Diamond Award (Invention) and Gold Award In: Invention, Innovation & Design Exposition (iidex), 25-29 September 2017, UiTM, Shah Alam.
2017
Ang, G. Y., C. Y. Yu, A. M. Khalid, M. N. F. Norizhab & M. Z. Salleh (2017). ExerNutrix – A sports genomics & nutrigenomics genotyping kit. Gold Award In: Invention, Innovation & Design Exposition (iidex), 25-29 September 2017, UiTM, Shah Alam.
2013
Chan, Y. Y., G. Y. Ang, C. Y. Yu & B. Kamarudin (2013). Oligo-CT Strip: Rapid test for sequence-specific detection of cholera toxin gene from toxigenic Vibrio cholerae. Gold Medal in: International Exhibitions of Ideas, Invention and Innovations Trade Fair (iENA), 31 October-3 November 2013, Messe, Nuremberg, Germany.
2013
Chan, Y. Y., G. Y. Ang & C. Y. Yu (2013). Device and method for detection of nucleic acid(s). Finalis in: Anugerah Harta Intelek Negara (Kategori Paten).
2012
Chan, Y. Y., G. Y. Ang, C. Y. Yu & B. Kamarudin (2012). Oligo-CT Strip: Rapid test for sequence-specific detection of cholera toxin gene from toxigenic Vibrio cholerae. Gold Medal in: Malaysia Technology Expo (MTE), 16-18 February 2012, Putra World Trade Centre, Kuala Lumpur.
RESEARCH AREA
Antibiotic resistance
Antimicrobial resistance
Biochemistry and Molecular Biology
Biosensors
Comparative genomics
COVID-19
CRISPR
DNA Biosensor
Electrochemical genosensor
Enzyme-based biosensors
Genetic polymorphism
Infectious diseases
Lateral flow strip biosensor
Lateral flow immunoassays
Medical biotechnology
Molecular diagnostics
Molecular microbiology
Next-generation sequencing (NGS)
Rapid diagnostics
Genetics and genomics
SARS-CoV-2
PATENT
2012
Chan, Y. Y., G. Y. Ang & C. Y. Yu (2012). Device and method for detection of nucleic acid(s). International Patent PCT/MY2013/000029.
2012
Chan, Y. Y., G. Y. Ang & C. Y. Yu (2012). Device and method for detection of nucleic acid(s). Malaysia Patent PI 2012000667.
PUBLICATION
Lee, T.Y., Lim, W.F., Ang, G.Y., Yu, C.Y., 2023. Genomic Surveillance of SARS-CoV-2 in Malaysia during the Era of Endemic COVID-19. Life.

Ang GY, Chan KG, Yean CY, Yu CY. Lateral Flow Immunoassays for SARS-CoV-2. Diagnostics. 2022; 12(11):2854. https://doi.org/10.3390/diagnostics12112854

Yu, C. Y., Wong, S. Y., Liew, N. W. C., Joseph, N., Zakaria, Z., Nurulfiza, I., Soe, H. J., Kairon, R., Amin-Nordin, S., & Chee, H. Y. (2022). Whole genome sequencing analysis of SARS-CoV-2 from Malaysia: From alpha to Omicron [Original Research]. Frontiers in Medicine, 9.

Saidi, N. F., Tan, C. H., Raja Azidin, R. M. F., Ismail, H., Yu, C. Y., & Ang, G. Y. (2022). Associations between speed, power and endurance performance in super league soccer players. Malaysian Journal of Sport Science and Recreation (MJSSR); Vol 18 No 2 (2022): Vol.18 No.2 September 2022DO - 10.24191/mjssr.v18i2.19553.

Chan, K.G., Ang, G.Y., Yu, C.Y., Yean, C.Y., 2021. Harnessing CRISPR-Cas to Combat COVID-19: From Diagnostics to Therapeutics. Life 11(11).

Yu, C.Y., Chan, K.G., Yean, C.Y., Ang, G.Y., 2021. Nucleic Acid-Based Diagnostic Tests for the Detection SARS-CoV-2: An Update. Diagnostics 11(1).

Mohd Amiruddin, M.N., Ang, G.Y., Yu, C.Y., Falero-Diaz, G., Otero, O., Reyes, F., Camacho, F., Chin, K.L., Sarmiento, M.E., Norazmi, M.N., Acosta, A., Yean Yean, C. (2020). Development of an immunochromatographic lateral flow dipstick for the detection of Mycobacterium tuberculosis 16 kDa antigen (Mtb-strip). Journal of Microbiological Methods 176, 106003.

Omasanggar, R., Yu, C.Y., Ang, G.Y., Emran, N.A., Kitan, N., Baghawi, A., Falparado Ahmad, A., Abdullah, M.A., Teh, L.K., Maniam, S. (2020). Mitochondrial DNA mutations in Malaysian female breast cancer patients. PLOS ONE 15(5), e0233461.

Ching, Y.K., Chin, Y.S., Appukutty, M., Ramanchadran, V., Yu, C.Y., Ang, G.Y., et al. (2019). Interaction of dietary linoleic acid and α-linolenic acids with rs174547 in FADS1 gene on metabolic syndrome components among vegetarians. Nutrients 11(7):1686.

Ang, G.Y., Yu, C.Y., Johari James, R., Ahmad, A., Abdul Rahman, T., Mohd Nor, F., Shaari, S.A., Ismail, A.I., Teh, L.K., & Salleh, M.Z. (2018). A study on the genetic polymorphisms of CYP3A5 among the Orang Asli in Malaysia using a next generation sequencing platform. Annals of Human Biology, 1-4.

Chin, P.S., Ang, G.Y., Yu, C.Y., Tan, E.L., Tee, K.K., Yin, W.F., Chan, K.G., Tan, G.Y.A. (2018). Prevalence, antimicrobial resistance, and genetic diversity of Listeria spp. isolated from raw chicken meat and chicken-related products in Malaysia. Journal of Food Protection 81:284-289.

Razali, R.H., Khoruddin, N.A., Jamari, H., Ang, G.Y., Yu, C.Y., James, R.J., Teh, K.H., Ibrahim, H.M., The, L.K., Salleh, M.Z. (2018). Understanding the genetic risk of childhood leukemia among the Orang Asli and Malay in Malaysia: Mining the whole genome sequence database. Malaysian Journal of Biochemistry and Molecular Biology (2):38-42.

Hong, K.W., Asmah Hani, A.W., Nurul Aina Murni, C.A., Pusparani, R.R., Chong, C.K., Verasahib, K., Yusoff, W.N.W., Noordin, N.M., Tee, K.K., Yin, W.F., Yu, C.Y., Ang, G.Y., Chan, K.G. (2017). Comparative genomic and phylogenetic analysis of a toxigenic clinical isolate of Corynebacterium diphtheriae strain B-D-16-78 from Malaysia. Infection Genetics and Evolution 54, 263-270.

Chong TM, Chen J-W, See-Too W-S, Yu C-Y, Ang G-Y, Lim YL, Yin W-F, Grandclément C, Faure D, Dessaux Y, et al. (2017). Phenotypic and genomic survey on organic acid utilization profile of Pseudomonas mendocina strain S5.2, a vineyard soil isolate. AMB Express.7:138.

Yu, C.Y., Ang, G.Y., Subramaniam, V., Johari James, R., Ahmad, A., Abdul Rahman, T., Mohd Nor, F., Shaari, S.A., Teh, L.K., Salleh, M.Z., (2017). Inference of the genetic polymorphisms of CYP2D6 in six subtribes of the Malaysian Orang Asli from whole-genome sequencing data. Genetic Testing and Molecular Biomarkers. 21: 409-415.

Chin, P.S., Yu, C.Y., Ang, G.Y., Yin, W.F., Chna, K-G. (2017). Draft genome sequence of a multidrug resistant Salmonella enterica serovar Brancaster strain PS01 isolated from chicken meat, Malaysia. Journal of Global Antimicrobial Resistance. 9: 41-2.

Yu, C.Y., Ang, G.Y., Chong, T.M., Chin, P.S., Ngeow, Y.F., Yin, W.F., Chan, K-G. (2017). Complete genome sequencing revealed novel genetic contexts of the mcr-1 gene in Escherichia coli strains. Journal of Antimicrobial Chemotherapy. 72, 1253-1255.

Ang, G.Y., Yu, C.Y., Subramaniam, V., Abdul Khalid, M.I.H., Ismail, M.I., Tuan Abdu Aziz, T.A., James Johari, M.R., Ahmad, A., Abdul Rahman, T., Mohd Nor. F., Shaari, Ismail, A.I., Isa, K.M., Salleh, H., The, L.K., Salleh, M.Z. (2016). Detection of CYP2C19 genetic variants in Malaysian Orang Asli from massively parallel sequencing data. PloS One, 11, e0164169.

Kamaluddin, N.R., Esa, E., Yusoff, Y.M., Ismail, A., Ang, G.Y., Yu, C.Y., Chan, K-G., Zakaria, Z. (2016). Identification of chromosomal translocations in childhood leukaemia using multiplex RT-PCR: a single institution study in multi-ethnic Malaysia. International Journal of Health Science and Research, 6, 52-6.

Yu, C.Y., Ang, G.Y., Ngeow, Y.F., Tee, K.K., Yin, W-F, Chan, K-G. (2016). Genome sequences of two multidrug-resistant Proteus mirabilis strains harboring CTX-M-65 isolated from Malaysia. Genome Announcements, 4, e01301-16.

Teh, L.K., Subramaniam, V., Tuan Abdu Aziz, T.A., Lee, L.S., Ismail, MI.., Yu, C.Y., Ang, G.Y., James Johari, M.R., Ismet, R.I., Sahak, N.S., Ahmad, A., Abdul Rahman, T., Mohd Nor. F., Shaari, S., Omar, M., Ismail, AI., Isa, K.M., Salleh, H., Salleh, M.Z (2016).
Systematic characterisation and comparison of the CYP2C9 variability of the orang asli in Malaysia with 12 populations. Drug Metabolism and Pharmacokinetics, 31, 304-313.

Yu, C.Y., Ang, G.Y., Chin, P.S., Ngeow, Y.F., Yin, W-F., Chan, K-G. (2016). Emergence of mcr-1-mediated colistin resistance in Escherichia coli in Malaysia. International Journal of Antimicrobial Agents, 47, 504-505.

Ang, G.Y., Yu, C.Y., Yong, D.A., Cheong, Y.M., Yin, W-F., Chan, K-G. (2016). Draft genome sequence of Neisseria gonorrhoeae strain NG_869 with penicillin, tetracycline and ciprofloxacin resistance determinants isolated from Malaysia. Indian Journal of Microbiology, 56, 225-227.

Lim, Y.L., Ee, R., Yong, D., Yu, C.Y., Ang, G.Y., Tee, K.K., Yin, W.F., Chan, K-G. (2016). Complete genome sequence analysis of Pandoraea pnomenusa type strain DSM 16536T isolated from a cystic fibrosis patient. Frontiers in Microbiology, 7, 109.

Yu, C.Y., Ang, G.Y., Cheng, H.J., Cheong, Y.M., Yin, W-F. & Chan, K-G. (2016). Draft genome sequence of a multi-drug resistant Chryseobacterium indologenes isolate from Malaysia. Genomics Data, 7, 185-186.

Chan, K-G., Yong, D., Ee, R., Lim, Y-L., Yu, C-Y., Tee, K-K., Yin, W-F. & Ang, G-Y. (2016). Complete genome sequence of Pandoraea oxalativorans DSM 23570T, an oxalate metabolizing soil bacterium. Journal of Biotechnology, 219, 124-125.

Ang, G.Y., Yu, C.Y., Cheong, Y.M., Yin, W-F. & Chan, K-G. (2016). Emergence of ST119 Acinetobacter pittii co-harbouring NDM-1 and OXA-58 in Malaysia. International Journal of Antimicrobial Agents, 47, 168-169.

Yong, D., Ee, R., Lim, Y-L., Yu, C-Y., Ang, G-Y., How, K-Y., Tee, K-K., Yin, W-F. & Chan, K-G. (2016). Complete genome sequence of Pandoraea thiooxydans DSM 25325T, a thiolsulfate-oxidizing bacterium. Journal of Biotechnology, 217, 51-52.

Ang, G.Y., Yu, C.Y., Chan, K.G., K.K., Banga Singh & Yean, C.Y. (2015). Development of a dry-reagent-based nucleic acid-sensing platform by coupling thermostabilised LATE-PCR assay to an oligonucleotide-modified lateral flow biosensor. Journal of Microbiological Methods, 118, 99-105.

Yu, C.Y., Ang, G.Y., Chan, K.K., Banga Singh, K.K. & Chan, Y.Y. (2015). Enzymatic electrochemical detection of epidemic-causing Vibrio cholerae with a disposable oligonucleotide-modified screen-printed bisensor coupled to a dry-reagent-based nucleic acid amplification assay. Biosensors and Bioelectronics, 70(0), 282-288.

Ang, S.H., Yu, C.Y., Ang, G.Y., Chan, Y.Y., Alias, Y.b., Khor, S.M. (2015). A colloidal gold-based lateral flow immunoassay for direct determination of haemoglobin A1c in whole blood. Analytical Methods, 7(9), 3972-3980.

Yu, C. Y., G. Y. Ang & C. Y. Yean (2013). Multiplex electrochemical genosensor for identifying toxigenic Vibrio cholerae serogroups O1 and O139. Chemical Communications (Camb), 49 (20), 2019-2021.

Ang, G. Y., C. Y. Yu & C. Y. Yean (2012). Ambient temperature detection of PCR amplicons with a novel sequence-specific nucleic acid lateral flow biosensor. Biosensors and Bioelectronics, 38,151-156.

Hamzah, I. H., C. Y. Yu, S. Korakkottil Kunhi Mohd, A. Abdul Manaf, O. Sidek & Y. Y. Chan (2012). Fabrication and characterization of poly(dimethyl)siloxane (PDMS)-flame retardant 4 (FR4) label free DNA sensor. Proceedings of International Conference on Agricultural, Biotechnology, Biological and Biosystems Engineering, 61, 613-620.

Yu, C. Y., G. Y. Ang, A. L. Chua, E. H. Tan, S. Y. Lee, G. Falero-Diaz, O. Otero, I. Rodriguez, F. Reyes, A. Acosta, M. E. Sarmiento, S. Ghosh, T. Ramamurthy, C. Yean Yean, P. Lalitha & M. Ravichandran (2011). Dry-reagent gold nanoparticle-based lateral flow biosensor for the simultaneous detection of Vibrio cholerae serogroups O1 and O139. Journal of Microbiological Methods, 86, 277-282.

Ang, G. Y., C. Y. Yu, K. Balqis, E. H. Tan, H. Azura, M. H. Hani, & C. Y. Yean (2010). Molecular evidence of cholera outbreak caused by a toxigenic Vibrio cholerae O1 El Tor variant strain in Kelantan, Malaysia. Journal of Clinical Microbiology, 48, 3963-3969.

Hamzah, I. H., C. Y. Yu, A. Abd Manaf, Sidek O. & Y. Y. Chan (2010). The effect of photoresist thin film on cyclic voltammetry measurement for DNA immobilization and hybridization of indicator-free DNA Sensor. Optoelectronics and Advanced Materials - Rapid Communications, 2103-2107.

Hamzah, I. H., C. Y. Yu, A. Abd Manaf, Sidek O. & Y. Y. Chan (2010). Performance characteristics study of fabricated Au/Ti sensor by using ferricyanide redox reaction for DNA hybridization detection. Biohealth Science Bulletin, 2(2), 52-56.

Yee, Y.C., Cin, L.S., 2021. Selangor Darul Ehsan. In: Wang, I., Ninomiya, H., Gussen, B. (Eds.), Sharing Cities 2020: A Case-Based Approach, pp. 99-100. Springer Singapore, Singapore.

Ang, G. Y., C. Y. Yu & C. Y. Yean. (2017). The hurdles in making diagnostics accessible to the bottom billions: can lateral flow immunoassays make a difference? p. 1-29. In: Asma I, Norazmi MN, Jafri MA, Armando A, Maria ES (ed.), Sustainable diagnostics for low-resource areas: Penerbit USM.

Yu, C. Y., G. Y. Ang & C. Y. Yean (2012). Genetic analysis of CTX prophage and antibiotic resistance determinants in Vibrio cholerae O1 belonging to the atypical El Tor biotype from Kelantan, Malaysia, p. 75-90. In S. J. Thatha (ed.), Cholera. InTech.