A
PROFILE
Laman Web Staf UPM
PROF. MADYA DR. YONG YOKE KEONG
PROFESOR MADYA
FAKULTI PERUBATAN DAN SAINS KESIHATAN
yoke_keong@upm.edu.my
Laman Web UPM
PROFILE
yoke_keong
BM
EN

PROFESIONAL

NAMA :
(Prof. Madya Dr.) YONG YOKE KEONG
JAWATAN :
PROFESOR MADYA
PTJ :
FAKULTI PERUBATAN DAN SAINS KESIHATAN

BIDANG PENYELIAAN
CANCER BIOLOGY AND ONCOLOGY / HUMAN PHYSIOLOGY / IMMUNOPHARMACOLOGY / PHARMACOLOGY / TOXICOLOGY
PENDIDIKAN
PHD IN BIOMEDICAL SCIENCES
UNIVERSITI PUTRA MALAYSIA, SERDANG, SELANGOR
Graduated : 2012
BACHELOR OF SCIENCE (BIOMEDICAL SCIENCE)
UNIVERSITI PUTRA MALAYSIA, SERDANG, SELANGOR
Graduated : 2007
PENERBITAN JOURNAL
1. Bixa orellana leaf extract suppress histamine-induced endothelial hyperpermeability via the PLC-NO-cGMP signaling cascade
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
2. Anti-inflammatory and wound healing properties of Malaysia Tualang honey
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
3. Stachytarpheta jamaicensis (L.) Vahl: From Traditional Usage to Pharmacological Evidence
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
4. Tualang Honey Improves Human Corneal Epithelial Progenitor Cell Migration and Cellular Resistance to Oxidative Stress In Vitro
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
5. Interferon-γ induces biphasic changes in caldesmon localization as well as adherens junction organization and expression in HUVECs
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
6. Water extract of Clinacanthus nutans leaves exhibits in vitro, ex vivo and in vivo anti-angiogenic activities in endothelial cell via suppression of cell proliferation
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
7. Anti-inflammatory properties of Bixa Orellana leaves extract are associated with suppression of bradykinin-induced endothelial hyperpermeability
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
8. Silver nanoparticles Clinacanthus nutans leaves extract induced apoptosis towards oral squamous cell carcinoma cell lines
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
9. Guided evaluation and standardisation of mesenchymal stem cell culture conditions to generate conditioned medium favourable to cardiac c-kit cell growth
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
10. Regression of solid breast tumours in mice by Newcastle disease virus is associated with production of apoptosis related-cytokines
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
11. Asiatic acid stabilizes cytoskeletal proteins and prevents TNF-α-induced disorganization of cell-cell junctions in human aortic endothelial cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
12. Malaysian Tualang Honey and Its Potential Anti-Cancer Properties: A Review
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
13. Malaysian Tualang Honey Inhibits Hydrogen Peroxide-Induced Endothelial Hyperpermeability
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
14. Human Wharton’s Jelly-Derived Mesenchymal Stem Cells Minimally Improve the Growth Kinetics and Cardiomyocyte Differentiation of Aged Murine Cardiac c-kit Cells in In Vitro without Rejuvenating Effect
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
15. Role of vascular permeability and its signaling cascade in inflammation
    Journal type: Citation-Indexed - Scopus
16. Biocompatible Nutmeg Oil-Loaded Nanoemulsion as Phyto-Repellent
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
17. Cytoprotective Role of Omentin Against Oxidative Stress-Induced Vascular Endothelial Cells Injury
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
18. Network Pharmacology of miR-146a-5p as a Potential Anti-Inflammatory Agent in Preventing Alzheimer's Disease
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
19. Comparison of antioxidant levels and anti-inflammatory activities of kelulut honey harvested at different month of intervals and its chemical compositions
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
20. Essential Oils Derived from Momordica charantia Seeds Exhibited Antiulcer Activity against Hydrogen Chloride/Ethanol and Indomethacin
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
21. Biogenic Silver Nanoparticles of Clinacanthus nutans as Antioxidant with Antimicrobial and Cytotoxic Effects
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
22. Immunomodulatory potential of Clinacanthus nutans extracts in the co-culture of triple-negative breast cancer cells, MDA-MB-231, and THP-1 macrophages
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
23. Gastroprotective Effect of Polypeptide-K Isolated from Momordica charantia’s Seeds on Multiple Experimental Gastric Ulcer Models in Rats
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
24. Vibrational Spectroscopy-Based Chemometrics Analysis of Clinacanthus nutans Extracts after Postharvest Processing and Extract Effects on Cardiac C-Kit Cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
25. Protective Effects of Alternanthera sessilis Ethanolic Extract against TNF-α or H2O2-Induced Endothelial Activation in Human Aortic Endothelial Cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
26. Malaysian Tualang Honey Suppresses the Angiogenic Events in Endothelial Cells Induced by Vascular Endothelial Growth Factor
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
27. Vascular Protective Effect and Its Possible Mechanism of Action on Selected Active Phytocompounds: A Review
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
28. Adverse effects of Bisphenol A on the liver and its underlying mechanisms: Evidence from in vivo and in vitro studies
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
29. Bisphenol A is a carcinogen that induces lipid accumulation, peroxisome proliferator‑activated receptor‑γ expression and liver disease
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
30. Large animal models for cardiac remuscularization studies: A methodological review
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
31. Network Pharmacology and Molecular Docking Analysis of Active Compounds in Tualang Honey against Atherosclerosis
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
32. Tualang and Kelulut Honey Reduced Lipopolysaccharides-stimulated Inflammatory Responses of Microglia
    Journal type: Citation-Indexed - Scopus
33. Alternanthera sessilis: A Review of Literature on the Phytoconstituents, Traditional Usage and Pharmacological Activities of Green and Red Cultivar
    Journal type: Citation-Indexed Journal - ESCI
34. Bombesin-like receptor 3 expression induced by bisphenol A is likely associated with reduced cell proliferation by inhibiting DNA synthesis and inducing inflammation in liver cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
35. Formation of Inclusion Complex of Curcumin and Tetrahydrocurcumin Prevents Angiogenesis by Inhibiting VEGF Activity: An in-silico Study
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
36. Network Pharmacology and Molecular Docking Approaches of Astaxanthin (ATX) against Atherosclerosis
    Journal type: Citation-Indexed Journal - ESCI
37. Clinacanthus nutans crude polysaccharide extract as a green platform for microwave-assisted synthesis of silver nanoparticles: Optimization, characterization, and evaluation of bioactivities
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
38. Zinc Nanostructure: A Short Review on Phytochemicals-Mediated Biogenic Synthesis and Its Anti-Inflammatory Effects
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
39. Medicinal activities of Tualang honey: a systematic review
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
40. MESENCHYMAL STEM CELLS-DERIVED EXOSOMAL MIRNAS TARGETING MICROGLIA IN TREATING NEUROINFLAMMATION AND NEUROLOGICAL DISEASES
    Journal type: Citation-Indexed - Scopus
41. Deciphering the potential mechanisms of Alternanthera sessilis red against atherosclerosis by integrating LC-MS/MS method, network pharmacology and molecular docking approaches
    Journal type: Citation-Indexed - Scopus
42. Astaxanthin’s Anti-Angiogenic Effects: Network Pharmacology and Functional Validation in Endothelial Cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
43. A new insight into cardiovascular protective potentials of hydroxylated xanthones
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
44. A Mini Review: Zinc Oxide NPs as a Promising Cancer Treatment Strategy: Insights into Synthesis Methodology and Mechanisms
    Journal type: Citation-Indexed - Scopus
45. Exploring the role of Bisphenol A in obesity-driven colorectal cancer progression: network toxicology and multi-organ pathology in animal models
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
46. Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
47. Nanoscale strategies: doxorubicin resistance challenges and enhancing cancer therapy with advanced nanotechnological approaches
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
PENERBITAN
2025
Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum
2025
A new insight into cardiovascular protective potentials of hydroxylated xanthones
2025
Astaxanthin’s Anti-Angiogenic Effects: Network Pharmacology and Functional Validation in Endothelial Cells
2025
Exploring the role of Bisphenol A in obesity-driven colorectal cancer progression: network toxicology and multi-organ pathology in animal models
2025
A Mini Review: Zinc Oxide NPs as a Promising Cancer Treatment Strategy: Insights into Synthesis Methodology and Mechanisms
2024
Zinc Nanostructure: A Short Review on Phytochemicals-Mediated Biogenic Synthesis and Its Anti-Inflammatory Effects
2024
MESENCHYMAL STEM CELLS-DERIVED EXOSOMAL MIRNAS TARGETING MICROGLIA IN TREATING NEUROINFLAMMATION AND NEUROLOGICAL DISEASES
2024
Clinacanthus nutans crude polysaccharide extract as a green platform for microwave-assisted synthesis of silver nanoparticles: Optimization, characterization, and evaluation of bioactivities
2024
Deciphering the potential mechanisms of Alternanthera sessilis red against atherosclerosis by integrating LC-MS/MS method, network pharmacology and molecular docking approaches
2024
Formation of Inclusion Complex of Curcumin and Tetrahydrocurcumin Prevents Angiogenesis by Inhibiting VEGF Activity: An in-silico Study
2024
Bombesin-like receptor 3 expression induced by bisphenol A is likely associated with reduced cell proliferation by inhibiting DNA synthesis and inducing inflammation in liver cells
2024
Medicinal activities of Tualang honey: a systematic review
2023
Tualang and Kelulut Honey Reduced Lipopolysaccharides-stimulated Inflammatory Responses of Microglia
2023
Large animal models for cardiac remuscularization studies: A methodological review
2023
Network Pharmacology and Molecular Docking Analysis of Active Compounds in Tualang Honey against Atherosclerosis
2022
Malaysian Tualang Honey Suppresses the Angiogenic Events in Endothelial Cells Induced by Vascular Endothelial Growth Factor
2022
Adverse effects of Bisphenol A on the liver and its underlying mechanisms: Evidence from in vivo and in vitro studies
2022
Bisphenol A is a carcinogen that induces lipid accumulation, peroxisome proliferator?activated receptor?? expression and liver disease
2022
Synthesis of Zinc Oxide Nanoparticles with Bioflavonoid Rutin: Characterisation, Antioxidant and Antimicrobial Activities and In Vivo Cytotoxic Effects on Artemia nauplii
2022
Vascular Protective Effect and Its Possible Mechanism of Action on Selected Active Phytocompounds: A Review
2022
Vibrational Spectroscopy-Based Chemometrics Analysis of Clinacanthus nutans Extracts after Postharvest Processing and Extract Effects on Cardiac C-Kit Cells
2022
Gastroprotective Effect of Polypeptide-K Isolated from Momordica charantia’s Seeds on Multiple Experimental Gastric Ulcer Models in Rats
2022
Protective Effects of Alternanthera sessilis Ethanolic Extract against TNF-? or H2O2-Induced Endothelial Activation in Human Aortic Endothelial Cells
2021
Essential Oils Derived from Momordica charantia Seeds Exhibited Antiulcer Activity against Hydrogen Chloride/Ethanol and Indomethacin
2021
Immunomodulatory potential of Clinacanthus nutans extracts in the co-culture of triple-negative breast cancer cells, MDA-MB-231, and THP-1 macrophages
2021
Biogenic Silver Nanoparticles of Clinacanthus nutans as Antioxidant with Antimicrobial and Cytotoxic Effects
2020
Cytoprotective Role of Omentin Against Oxidative Stress-Induced Vascular Endothelial Cells Injury
2020
Biocompatible Nutmeg Oil-Loaded Nanoemulsion as Phyto-Repellent
2020
Comparison of antioxidant levels and anti-inflammatory activities of kelulut honey harvested at different month of intervals and its chemical compositions
2019
Human Mesenchymal Stem Cells Minimally Improved the Growth Kinetics of Aged Murine Cardiac c-kit Cells in Vitro
2019
Malaysian Tualang Honey Inhibits Hydrogen Peroxide-Induced Endothelial Hyperpermeability
2019
Silver nanoparticles Clinacanthus nutans leaves extract induced apoptosis towards oral squamous cell carcinoma cell lines
2019
Regression of solid breast tumours in mice by Newcastle disease virus is associated with production of apoptosis related-cytokines
2019
Human Wharton’s Jelly-Derived Mesenchymal Stem Cells Minimally Improve the Growth Kinetics and Cardiomyocyte Differentiation of Aged Murine Cardiac c-kit Cells in In Vitro without Rejuvenating Effect
2019
Role of vascular permeability and its signaling cascade in inflammation
2019
Asiatic acid stabilizes cytoskeletal proteins and prevents TNF-?-induced disorganization of cell-cell junctions in human aortic endothelial cells
2019
Guided evaluation and standardisation of mesenchymal stem cell culture conditions to generate conditioned medium favourable to cardiac c-kit cell growth
2018
Interferon-? induces biphasic changes in caldesmon localization as well as adherens junction organization and expression in HUVECs
2018
Malaysian Tualang Honey and Its Potential Anti-Cancer Properties: A Review
2018
Anti-inflammatory properties of Bixa Orellana leaves extract are associated with suppression of bradykinin-induced endothelial hyperpermeability
2018
Water extract of Clinacanthus nutans leaves exhibits in vitro, ex vivo and in vivo anti-angiogenic activities in endothelial cell via suppression of cell proliferation
2017
Antiulcer activity of essential oils derived from Momordica charantia seeds against hydrogen chloride/ethanol and indomethacin-induced gastric ulcers
2017
Anti-Inflammatory Properties of Bixa Orellana Leaves Extract Are Associated With Suppression of Bradykinin-Induced Endothelial Hyperpermeability
2017
Apoptosis Effects Of Silver Nanoparticle Clinacanthus Nutans Leaves Extracts Towards Oral Squamous Cell Carcinoma Cell Lines
2017
Conditioned Medium from Bone Marrow-derived Mesenchymal Stem Cells: Standardization of Culture Conditions for In Vitro Expansion of Cardiac C-kit Cells (CTR-17-0544)
2017
Water extract of Clinacanthus nutans leaf exhibits in vitro, ex-vivo and in vivo anti-angiogenic activity in endothelial cell via suppression of cell proliferation
2016
Anti-inflammatory and wound healing properties of Malaysia Tualang honey
2016
Stachtarpheta jamaicensis (L.) Vahl: from Traditional Usage to Pharmacological Evidences
2016
Stachytarpheta jamaicensis (L.) Vahl: From Traditional Usage to Pharmacological Evidence
2015
Bixa orellana leaf extract suppress histamine-induced endothelial hyperpermeability via the PLC-NO-cGMP signaling cascade
2014
Tualang Honey Improves Human Corneal Epithelial Progenitor Cell Migration and Cellular Resistance to Oxidative Stress In Vitro