A
PROFILE
UPM's Staff Profile
YBHG. PROFESOR DR. TAN WEN SIANG
FACULTY OF BIOTECHNOLOGY AND BIOMOLECULAR SCIENCES
wstan@upm.edu.my
UPM WEBSITE
PROFILE
wstan
BM
EN

PROFESSIONAL

NAME :
(Ybhg. Profesor Dr.) Tan Wen Siang
POSITION :
Profesor
ENTITY :
Faculty Of Biotechnology And Biomolecular Sciences

PUBLICATION
2025:
Proteomic profiling of the Macrobrachium rosenbergii nodavirus infection: A study of early to late-stage infection in vitro
2025:
Broadly cross-reactive immune responses in chickens immunized with chimeric virus-like particles of nodavirus displaying the M2e originated from avian and human influenza A viruses
2025:
Chimeric virus-like particles of nodavirus displaying M2e of human and avian influenza A viruses as a potential dual-use vaccine: Inducing a broader immune response and protecting mice against viral infections
2023:
Meta-analysis of studies on protection provided by different prophylactic agents, their routes of administration and incubation times against nodavirus infection in Macrobrachium rosenbergii
2023:
Next-generation viral nanoparticles for targeted delivery of therapeutics: Fundamentals, methods, biomedical applications, and challenges
2023:
Genomic analysis and biological characterization of a novel Schitoviridae phage infecting Vibrio alginolyticus
2022:
Challenges and Complications of Poly(lactic-co-glycolic acid)-Based Long-Acting Drug Product Development
2022:
Virus-like particles of Macrobrachium rosenbergii nodavirus: Particle size and capsid protein assembly domain
2022:
Quartz crystal microbalance-based biosensing of hepatitis B antigen using a molecularly imprinted polydopamine film
2021:
Hepatitis B virus-like particle: targeted delivery of plasmid expressing short hairpin RNA for silencing the Bcl-2 gene in cervical cancer cells
2021:
Chimeric Virus-like Particles of Prawn Nodavirus Displaying Hepatitis B Virus Immunodominant Region: Biophysical Properties and Cytokine Response
2021:
Regulation of proteolytic activity to improve the recovery of Macrobrachium rosenbergii nodavirus capsid protein
2021:
The Macrobrachium rosenbergii nodavirus: a detailed review of structure, infectivity, host immunity, diagnosis and prevention
2020:
Stealth Coating of Nanoparticles in Drug Delivery System
2020:
Targeted Delivery of 5-Fluorouracil-1-Acetic Acid (5-FA) to Cancer Cells Overexpressing Epithelial Growth Factor Receptor (EGFR) using Virus-Like Nanoparticles
2020:
Advances in the Diagnosis of Foot-and-Mouth Disease
2020:
Immunological Analysis of the Hepatitis B Virus ‘a’ Determinant Displayed on Chimeric Virus-like Particles of Macrobrachium rosenbergii Nodavirus Capsid Protein Produced in Sf9 Cells
2020:
Quartz crystal microbalance-based biosensors as rapid diagnostic devices for infectious diseases
2019:
Thermally-responsive Virus-like Particle for Targeted Delivery of Cancer Drug
2019:
Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development
2019:
Recent Advances in the Vaccine Development against Middle East Respiratory Syndrome-coronavirus
2019:
Efficacy and potential of phage therapy against multidrug resistant Shigella spp.
2019:
Shielding of Hepatitis B Virus-Like Nanoparticle with Poly(2-ethyl-2-oxazoline)
2018:
A 12-residue epitope displayed on phage T7 reacts strongly with antibodies against foot-and-mouth disease virus
2018:
Peptide inhibitors of Macrobrachium rosenbergii nodavirus
2018:
A dual bioconjugated virus-like nanoparticle as a drug delivery system and comparison with a pH-responsive delivery system
2018:
Size-selective purification of hepatitis B virus-like particle in flow-through chromatography: Types of ion exchange adsorbent and grafted polymer architecture
2018:
Targeted Delivery of Cell Penetrating Peptide Virus-like Nanoparticles to Skin Cancer Cells
2018:
Purification of the recombinant enhanced green fluorescent protein from Escherichia coli using alcohol + salt aqueous two-phase systems
2017:
Biosensing of hepatitis B antigen with poly(acrylic acid) hydrogel immobilized with antigens and antibodies
2017:
Advances in the study of nodavirus
2017:
Tracking virus-like particles of Macrobrachium rosenbergii nodavirus in insect cells
2017:
Virus-like Particle of Macrobrachium rosenbergii Nodavirus Produced in Spodoptera frugiperda (Sf9) Cells is Distinctive from that Produced in Escherichia coli
2017:
A Simple Add-and-Display Method for Immobilisation of Cancer Drug on His-tagged Virus-like Nanoparticles for Controlled Drug Delivery
2016:
A versatile and economical method for the release of recombinant proteins from Escherichia coli by 1-propanol cell disruption
2016:
Negative chromatography of hepatitis B virus-like particle: comparative study of different adsorbent designs
2016:
Expression and purification of the matrix protein of Nipah virus in baculovirus-insect cell system
2016:
PH-responsive Virus-like Nanoparticles with Enhanced Tumour-targeting Ligands for Cancer Drug Delivery
2016:
Production of the virus-like particles of Nipah virus matrix protein in Pichia pastoris as diagnostic reagents
2015:
Potential recombinant vaccine against influenza A virus based on M2e displayed on nodaviral capsid nanoparticles
2015:
Purification of rabbit polyclonal immunoglobulin G with ammonium sulphate precipitation and mixed-mode chromatography
2015:
Induction of Humoral and Cell-Mediated Immune Responses by Hepatitis B Virus Epitope Displayed on the Virus-Like Particles of Prawn Nodavirus
2015:
Negative chromatography purification of hepatitis B virus-like particles using poly(oligo(ethylene glycol) methacrylate) grafted cationic adsorbent
2015:
An N-terminal extension to the hepatitis B virus core protein forms a poorly ordered trimeric spike in assembled virus-like particles
2015:
Hepatitis B virus peptide inhibitors: solution structures and interactions with the viral capsid
2014:
A potential universal vaccine against influenza A virus based on M2e displayed on nodaviral capsid nanoparticles
2014:
A single-step purification of the glycoprotein of Nipah virus produced in insect cells using an anion exchange chromatography method
2014:
RNA-binding region of Macrobrachium rosenbergii nodavirus capsid protein
2014:
Phage display creates innovative applications to combat hepatitis B virus
2014:
Biochemical and molecular identification of Enterococcus spp. from red pitaya
2013:
Enhancement of the yield of long helical structure of recombinant nucleocapsid protein of Newcastle disease virus
2013:
Solution structure and in silico binding of a cyclic peptide with hepatitis B surface antigen
2013:
Display of the VP1 epitope of foot-and-mouth disease virus on bacteriophage T7 and its application in diagnosis
2013:
Oligomerization state of the multimerization domain of Nipah virus phosphoprotein
2013:
Detection of hepatitis B virus core antigen by phage display mediated TaqMan real-time immuno-PCR
2013:
Purification of long helical capsid of Newcastle disease virus from Escherichia coli using anion exchange chromatography
2012:
Statistical optimization of green fluorescent protein production from Escherichia coli BL21 (DE3)
2012:
Mechanical cell disruption of Escherichia coli for the release of recombinant green fluorescent protein
2012:
Nanoglue: An alternative way to display cell-internalizing peptide at the spikes of hepatitis B virus core nanoparticles for cell-targeting delivery
2012:
Purification of recombinant hepatitis B core antigen from unclarified Escherichia coli feedstock using phage-immobilized expanded bed adsorption chromatography
2012:
Delivery of chimeric hepatitis B core particles into liver cells
2012:
Display of the antigenic region of Nipah virus nucleocapsid protein on hepatitis B virus capsid
2012:
Isolation and identification of lactic acid bacteria from fermented red dragon fruit juices
2011:
Virus-like particles of Macrobrachium rosenbergii nodavirus produced in bacteria
2011:
Production and purification of the phosphoprotein of Nipah virus in Escherichia coli for use in diagnostic assays
2011:
Production of long helical capsid of Nipah virus by Pichia pastoris
2010:
Purification of His-tagged hepatitis B core antigen from unclarified bacterial homogenate using immobilized metal affinity-expanded bed adsorption chromatography
2010:
Purification of bacteriophage M13 by anion exchange chromatography
2009:
Mutagenesis of the Nucleocapsid Protein of Nipah Virus Involved in Capsid Assembly
2009:
Display of Hepatitis B Virus PreS1 Peptide on bacteriophage T7 and Its Potential in Gene Delivery into HepG2 Cells
2009:
N-terminally His-tagged hepatitis B core antigens: construction, expression, purification and antigenicity
2009:
Production of the matrix protein of Nipah virus in Escherichia coli: virus-like particles and possible application in diagnosis
2008:
Recombinant hepatitis B virus core particles: association, dissociation and encapsidation of green fluorescent protein.
2007:
A phage-displayed single chain variable fragment that interacts with hepatitis B core antigen: library construction, selection and diagnosis
2005:
A phage-displayed cyclic peptide that interacts tightly with the immunodominant region of hepatitis B surface antigen
2005:
Antigenicity and immunogenicity of the immunodominant region of hepatitis B surface antigen displayed on bacteriophage T7
2003:
Selection of high affinity ligands to Hepatitis B core particles from a phage-displayed cyclic peptide library