PROFILE
Laman Web Staf UPM
YBHG. PROFESOR DR. TAN WEN SIANG
PROFESOR
FAKULTI BIOTEKNOLOGI DAN SAINS BIOMOLEKUL
wstan@upm.edu.my
PROFESIONAL
NAMA :
(Ybhg. Profesor Dr.) TAN WEN SIANG
JAWATAN :
PROFESOR
PTJ :
FAKULTI BIOTEKNOLOGI DAN SAINS BIOMOLEKUL
BIDANG PENYELIAAN
MEDICAL BIOTECHNOLOGY / MICROBIOLOGY / MOLECULAR BIOLOGY AND GENETIC ENGINEERING / NANOBIOTECHNOLOGY / VIROLOGY
PENERBITAN
2025
Proteomic profiling of the Macrobrachium rosenbergii nodavirus infection: A study of early to late-stage infection in vitro
2025
Broadly cross-reactive immune responses in chickens immunized with chimeric virus-like particles of nodavirus displaying the M2e originated from avian and human influenza A viruses
2025
Chimeric virus-like particles of nodavirus displaying M2e of human and avian influenza A viruses as a potential dual-use vaccine: Inducing a broader immune response and protecting mice against viral infections
2023
Meta-analysis of studies on protection provided by different prophylactic agents, their routes of administration and incubation times against nodavirus infection in Macrobrachium rosenbergii
2023
Next-generation viral nanoparticles for targeted delivery of therapeutics: Fundamentals, methods, biomedical applications, and challenges
2023
Genomic analysis and biological characterization of a novel Schitoviridae phage infecting Vibrio alginolyticus
2022
Challenges and Complications of Poly(lactic-co-glycolic acid)-Based Long-Acting Drug Product Development
2022
Virus-like particles of Macrobrachium rosenbergii nodavirus: Particle size and capsid protein assembly domain
2022
Quartz crystal microbalance-based biosensing of hepatitis B antigen using a molecularly imprinted polydopamine film
2021
Hepatitis B virus-like particle: targeted delivery of plasmid expressing short hairpin RNA for silencing the Bcl-2 gene in cervical cancer cells
2021
Chimeric Virus-like Particles of Prawn Nodavirus Displaying Hepatitis B Virus Immunodominant Region: Biophysical Properties and Cytokine Response
2021
Regulation of proteolytic activity to improve the recovery of Macrobrachium rosenbergii nodavirus capsid protein
2021
The Macrobrachium rosenbergii nodavirus: a detailed review of structure, infectivity, host immunity, diagnosis and prevention
2020
Stealth Coating of Nanoparticles in Drug Delivery System
2020
Targeted Delivery of 5-Fluorouracil-1-Acetic Acid (5-FA) to Cancer Cells Overexpressing Epithelial Growth Factor Receptor (EGFR) using Virus-Like Nanoparticles
2020
Advances in the Diagnosis of Foot-and-Mouth Disease
2020
Immunological Analysis of the Hepatitis B Virus ‘a’ Determinant Displayed on Chimeric Virus-like Particles of Macrobrachium rosenbergii Nodavirus Capsid Protein Produced in Sf9 Cells
2020
Quartz crystal microbalance-based biosensors as rapid diagnostic devices for infectious diseases
2019
Thermally-responsive Virus-like Particle for Targeted Delivery of Cancer Drug
2019
Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development
2019
Recent Advances in the Vaccine Development against Middle East Respiratory Syndrome-coronavirus
2019
Efficacy and potential of phage therapy against multidrug resistant Shigella spp.
2019
Shielding of Hepatitis B Virus-Like Nanoparticle with Poly(2-ethyl-2-oxazoline)
2018
A 12-residue epitope displayed on phage T7 reacts strongly with antibodies against foot-and-mouth disease virus
2018
Peptide inhibitors of Macrobrachium rosenbergii nodavirus
2018
A dual bioconjugated virus-like nanoparticle as a drug delivery system and comparison with a pH-responsive delivery system
2018
Size-selective purification of hepatitis B virus-like particle in flow-through chromatography: Types of ion exchange adsorbent and grafted polymer architecture
2018
Targeted Delivery of Cell Penetrating Peptide Virus-like Nanoparticles to Skin Cancer Cells
2018
Purification of the recombinant enhanced green fluorescent protein from Escherichia coli using alcohol + salt aqueous two-phase systems
2017
Biosensing of hepatitis B antigen with poly(acrylic acid) hydrogel immobilized with antigens and antibodies
2017
Advances in the study of nodavirus
2017
Tracking virus-like particles of Macrobrachium rosenbergii nodavirus in insect cells
2017
Virus-like Particle of Macrobrachium rosenbergii Nodavirus Produced in Spodoptera frugiperda (Sf9) Cells is Distinctive from that Produced in Escherichia coli
2017
A Simple Add-and-Display Method for Immobilisation of Cancer Drug on His-tagged Virus-like Nanoparticles for Controlled Drug Delivery
2016
A versatile and economical method for the release of recombinant proteins from Escherichia coli by 1-propanol cell disruption
2016
Negative chromatography of hepatitis B virus-like particle: comparative study of different adsorbent designs
2016
Expression and purification of the matrix protein of Nipah virus in baculovirus-insect cell system
2016
pH-responsive Virus-like Nanoparticles with Enhanced Tumour-targeting Ligands for Cancer Drug Delivery
2016
Production of the virus-like particles of Nipah virus matrix protein in Pichia pastoris as diagnostic reagents
2015
Potential recombinant vaccine against influenza A virus based on M2e displayed on nodaviral capsid nanoparticles
2015
Purification of rabbit polyclonal immunoglobulin G with ammonium sulphate precipitation and mixed-mode chromatography
2015
Induction of Humoral and Cell-Mediated Immune Responses by Hepatitis B Virus Epitope Displayed on the Virus-Like Particles of Prawn Nodavirus
2015
Negative chromatography purification of hepatitis B virus-like particles using poly(oligo(ethylene glycol) methacrylate) grafted cationic adsorbent
2015
An N-terminal extension to the hepatitis B virus core protein forms a poorly ordered trimeric spike in assembled virus-like particles
2015
Hepatitis B virus peptide inhibitors: solution structures and interactions with the viral capsid
2014
A potential universal vaccine against influenza A virus based on M2e displayed on nodaviral capsid nanoparticles
2014
A single-step purification of the glycoprotein of Nipah virus produced in insect cells using an anion exchange chromatography method
2014
RNA-binding region of Macrobrachium rosenbergii nodavirus capsid protein
2014
Phage display creates innovative applications to combat hepatitis B virus
2014
Biochemical and molecular identification of Enterococcus spp. from red pitaya
2013
Enhancement of the yield of long helical structure of recombinant nucleocapsid protein of Newcastle disease virus
2013
Solution structure and in silico binding of a cyclic peptide with hepatitis B surface antigen
2013
Display of the VP1 epitope of foot-and-mouth disease virus on bacteriophage T7 and its application in diagnosis
2013
Oligomerization state of the multimerization domain of Nipah virus phosphoprotein
2013
Detection of hepatitis B virus core antigen by phage display mediated TaqMan real-time immuno-PCR
2013
Purification of long helical capsid of Newcastle disease virus from Escherichia coli using anion exchange chromatography
2012
Statistical optimization of green fluorescent protein production from Escherichia coli BL21 (DE3)
2012
Mechanical cell disruption of Escherichia coli for the release of recombinant green fluorescent protein
2012
Nanoglue: An alternative way to display cell-internalizing peptide at the spikes of hepatitis B virus core nanoparticles for cell-targeting delivery
2012
Purification of recombinant hepatitis B core antigen from unclarified Escherichia coli feedstock using phage-immobilized expanded bed adsorption chromatography
2012
Delivery of chimeric hepatitis B core particles into liver cells
2012
Display of the antigenic region of Nipah virus nucleocapsid protein on hepatitis B virus capsid
2012
Isolation and identification of lactic acid bacteria from fermented red dragon fruit juices
2011
Virus-like particles of Macrobrachium rosenbergii nodavirus produced in bacteria
2011
Production and purification of the phosphoprotein of Nipah virus in Escherichia coli for use in diagnostic assays
2011
Production of long helical capsid of Nipah virus by Pichia pastoris
2010
Purification of His-tagged hepatitis B core antigen from unclarified bacterial homogenate using immobilized metal affinity-expanded bed adsorption chromatography
2010
Purification of bacteriophage M13 by anion exchange chromatography
2009
Mutagenesis of the Nucleocapsid Protein of Nipah Virus Involved in Capsid Assembly
2009
Display of Hepatitis B Virus PreS1 Peptide on bacteriophage T7 and Its Potential in Gene Delivery into HepG2 Cells
2009
N-terminally His-tagged hepatitis B core antigens: construction, expression, purification and antigenicity
2009
Production of the matrix protein of Nipah virus in Escherichia coli: virus-like particles and possible application in diagnosis
2008
Recombinant hepatitis B virus core particles: association, dissociation and encapsidation of green fluorescent protein.
2007
A phage-displayed single chain variable fragment that interacts with hepatitis B core antigen: library construction, selection and diagnosis
2005
A phage-displayed cyclic peptide that interacts tightly with the immunodominant region of hepatitis B surface antigen
2005
Antigenicity and immunogenicity of the immunodominant region of hepatitis B surface antigen displayed on bacteriophage T7
2003
Selection of high affinity ligands to Hepatitis B core particles from a phage-displayed cyclic peptide library