PROFILE
UPM's Staff Profile
DR. INTAN SAFINAR BINTI ISMAIL
RESEARCH FELLOW
INSTITUTE OF BIOSCIENCE
safinar@upm.edu.my
PROFESSIONAL
NAME :
(Dr.) INTAN SAFINAR BINTI ISMAIL
POST :
RESEARCH FELLOW
ENTITY :
INSTITUTE OF BIOSCIENCE
EDUCATIONAL BACKGROUND
2003
Okayama University, Japan - PhD
1997
University Putra Malaysia - MSc
1992
Creighton University, USA -BSc
WORKING EXPERIENCE
2013
Associate Professor, Dept. of Chemistry,
Faculty of Science, UPM
Faculty of Science, UPM
2005
Senior Lecturer, Dept. of Chemistry,
Faculty of Science, UPM
Faculty of Science, UPM
2004
Lecturer, School of Pharmaceutical Sciences, University Sains Malaysia, Penang
1998
R and D Chemist, Mustajab Ind., (Nona Roguy) Kedah
1996
R and D Executive, RAZA Manufacturing Bhd., (Pharmaniaga Bhd.) Selangor
1993
Quality Control Chemist, SM Pharmaceutical Bhd., Kedah
PUBLICATION
2024
Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers
2024
COMBINED KNEE OSTEOARTHRITIS AND DIABETES IS ASSOCIATED WITH REDUCED MUSCLE STRENGTH, PHYSICAL INACTIVITY, AND POORER QUALITY OF LIFE
2024
Comparative proteome analysis revealed potential biomarkers and the underlying immune mechanisms in Vibrio-resistant hybrid grouper, Epinephelus fuscoguttatus ??×?Epinephelus lanceolatus ?
2023
A Study of the Interaction between Xanthine Oxidase and Its Inhibitors from Chrysanthemum morifolium Using Computational Simulation and Multispectroscopic Methods
2023
Centella asiatica (L.) Urb. Extract ameliorates branched-chain amino acid (BCAA) metabolism in acute reserpine-induced stress zebrafish model via 1 H Nuclear Magnetic Resonance (NMR)-based metabolomics approach
2023
Immunomodulatory Effects of Isochrysis galbana Incorporated Diet on Oreochromis Sp. (Red Hybrid Tilapia) via Sera-1H NMR Metabolomics Study
2023
NMR- and LCMS-metabolomics studies on non-organic versus organic soybeans (Glycine max), and their fermentation by Rhizopus oligosporus
2023
Protective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity on human kidney cell (PCS-400-010) elucidated by LCMS based metabolomics approach
2023
Study on the acute toxicity of sodium taurocholate via zebrafish mortality, behavioral response, and NMR-metabolomics analysis
2023
Prophylactic effects of dietary Isochrysis galbana on immersion?challenged red hybrid tilapia (Oreochromis spp.) with Streptococcus agalactiae by spleen?NMR?metabolomics
2022
Indonesian Mangrove Sonneratia caseolaris Leaves Ethanol Extract Is a Potential Super Antioxidant and Anti Methicillin-Resistant Staphylococcus aureus Drug
2022
Synthesis of benzylated amine-substituted xanthone derivatives and their antioxidant and anti-inflammatory activities
2022
The Immunostimulant Effects of Isochrysis galbana Supplemented Diet on the Spleen of Red Hybrid Tilapia (Oreochromis spp.) Evaluated by Nuclear Magnetic Resonance Metabolomics
2022
Metabolomic Approach for Rapid Identification of Antioxidants in Clinacanthus nutans Leaves with Liver Protective Potential
2022
Skin mucus proteome analysis reveals disease-resistant biomarker signatures in hybrid grouper (Epinephelus fuscoguttatus ? x Epinephelus lanceolatus ?) against Vibrio alginolyticus
2021
Rapid characterisation of xanthine oxidase inhibitors from the flowers of Chrysanthemum morifolium Ramat. Using metabolomics approach
2021
Anti-inflammatory evaluation of Scurrula ferruginea (jack) danser parasitizing on Tecoma stans (L.) H.B.K. in LPS/IFN-?-induced RAW 264.7 macrophages
2021
Evaluation of Indonesian mangrove Xylocarpus granatum leaves ethyl acetate extract as potential anticancer drug
2021
Intermittent frying effect on French fries in palm olein, sunflower, soybean and canola oils on quality indices, 3-monochloropropane-1,2-diol esters (3-MCPDE), glycidyl esters (GE) and acrylamide contents
2021
Complementary analytical platforms of NMR spectroscopy and LCMS analysis in the metabolite profiling of Isochrysis galbana
2021
Multi-platform Metabolomics Analyses Revealed the Complexity of Serum Metabolites in LPS-induced Neuroinflammed Rats Treated with Clinacanthus nutans Aqueous Extract
2020
NMR and LCMS analytical platforms exhibited the nephroprotective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity in the in vitro condition
2020
Phytochemical and anti-inflammatory properties of Scurrula ferruginea (Jack) Danser parasitizing on three different host plants elucidated by NMR-based metabolomics
2020
Urine Untargeted Metabolomic Profiling Is Associated with the Dietary Pattern of Successful Aging among Malaysian Elderly
2020
Metabolite profiles of red and yellow watermelon (Citrullus lanatus) cultivars by 1H-NMR metabolomics approach
2020
The anti-neuroinflammatory effects of Clinacanthus nutans leaf extract on metabolism elucidated through 1H NMR in correlation with cytokines microarray
2020
Ultrasonic?Assisted Extraction of Phalerin from Phaleria macrocarpa: Response Surface Methodology and Artifcial Neural Network Modelling
2020
1 H NMR-Based Metabolomics of Clinacanthus nutans Leaves Extracts in Correlation with Their Anti-neuroinflammation Towards LPS-Induced BV2 Cells
2020
Potency of Selected Berries, Grapes and Citrus Fruit as Neuroprotective Agents
2020
In vitro cytotoxic, radical scavenging and antimicrobial activities of curcuma mangga valeton and van zijp
2020
Intermittent Fasting Enhanced the Cognitive Function in Older Adults with Mild Cognitive Impairment by Inducing Biochemical and Metabolic changes: A 3-Year Progressive Study
2020
Serum Metabolomics Profiling of Commercially Mixed Functional Foods—Effects in Beta-Amyloid Induced Rats Measured Using 1H NMR Spectroscopy
2019
Effects of Clinacanthus nutans leaf extract on lipopolysaccharide induced neuroinflammation in rats: A behavioral and 1 H NMR-based metabolomics study
2019
For Peer Review Only Verification and evaluation of monochloropropanediol (MCPD) esters and glycidyl esters in palm oil products o different regions in Malaysia
2019
Identification of anti-inflammatory compound/compounds in hexane fraction of Jatropha curcas root extract
2019
Cytotoxic xanthones isolated from Calophyllum depressinervosum and Calophyllum buxifolium with antioxidant and cytotoxic activities
2019
Verification and evaluation of monochloropropanediol (MCPD) esters and glycidyl esters in palm oil products of different regions in Malaysia
2019
Assessment of anti-neuroinflammatory effects of Clinacanthus nutans leaf extract elucidated through 1H NMR in correlation with cytokines microarray
2018
Effects of Clinacanthus nutans Leaf Extracts on Lipopolysaccharides (LPS)-induced Neuroinflammation Rats Observed via Behavioral Pattern and 1H NMR-based Metabolomics Approach
2018
XANTHONES FROM STEM BARK OF Garcinia rostrata
2018
Nitric oxide inhibitory and anti-Bacillus activity of phenolic compounds and plant extracts from Mesua species
2018
ROLE OF HERBAL MEDICINES IN VITILIGO TREATMENT - CURRENT STATUS AND FUTURE PERSPECTIVES
2018
Classification of Raw Stingless Bee Honeys by Bee Species Origins Using the NMR- and LC-MS-Based Metabolomics Approach
2018
In silico analysis of Mentha pipertia (phyto-constituents) as HMG coa reductase and squalene synthase inhibitors
2017
URINARY METABOLOMICS STUDY ON THE PROTECTIVE ROLE OF ORTHOSIPHON STAMINEUS IN STREPTOZOTOCIN INDUCED DIABETES MELLITUS IN RATS VIA 1HNMR SPECTROSCOPY
2017
Natural Compounds as Inhibitors of Plasmodium falciparum Enoyl-acyl Carrier Protein Reductase (PfENR): An In silico Study.
2017
Stability Study of Algerian Nigella sativa Seeds Stored under Different Conditions
2017
Urinary metabolic profiling of cisplatin nephrotoxicity and nephroprotective effects of Orthosiphon stamineus leaves elucidated by 1H NMR spectroscopy
2016
Stability Study of Algerian Nigella sativa Seeds Stored under Different Conditions
2015
Phytochemical and acute oral toxicity studies of Java tea leaf extracts
2015
Molecular docking analysis of selected Clinacanthus nutans constituents as XO, NOS, HNE, MMP 2, MMP 9 and SQS inhibitors
2014
Acute toxicity study and 1H NMR Metabolomics evaluation of Mentha piperita queous extract hypocholesterolemic properties on Wistar rats
2014
Molecular docking analysis of curcumin analogues as human neutrophil elastase inhibitors
2014
Optimization of Enzymatic Synthesis of 3-O-B-D-Glucopyranoside Betulinic Acid by Novozyme-435
2013
Phase Behaviour of Ternary System: Soybean Oil/Non-Ionic Surfactants/Deionized Water
2013
Steroids from Dysoxylum grande (Meliaceae) leaves
2013
Vasorelaxant activity of indole alkaloids from Tabernaemontana dichotoma
2013
Quantitative HPLC Analysis of Benzene Derivatives of Melicope ptelefolia Leaves
2013
Terpenes of Walsura chrysogyne (Meliaceae)
2011
Quantitative HPLC Analysis of Benzene Derivatives of Melicope ptelefolia Leaves
2011
(20S *,24S *)-25-Hydroxy-20,24-epoxy-A-homo-4-oxadammaran-3-one (Chrysura) isolated from the leaves ofWalsura chrysogyne
2011
Five Photosensitizing Pheophorbides and Two New Phloroglucinol Derivatives from Syzygium polyanthum (Salam) Leaves
2010
Ichthyotoxic properties and essential oils of Syzygium malaccense (Myrtaceae)
2009
Chrotacumines A-D, Chromone Alkaloids from Dysoxylum acutangulum
2009
Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum