A
PROFILE
UPM's Staff Profile
DR. SHARIFAH ALAWIEYAH BINTI SYED MORTADZA
SENIOR LECTURER
FACULTY OF BIOTECHNOLOGY AND BIOMOLECULAR SCIENCES
s_alawieyah@upm.edu.my
UPM WEBSITE
PROFILE
s_alawieyah
BM
EN

PROFESSIONAL

NAME :
(Dr.) SHARIFAH ALAWIEYAH BINTI SYED MORTADZA
POST :
SENIOR LECTURER
ENTITY :
FACULTY OF BIOTECHNOLOGY AND BIOMOLECULAR SCIENCES

FIELD OF SUPERVISION
IMMUNOBIOLOGY / NEUROSCIENCE / PHARMACOLOGY / TOXICOLOGY
EDUCATION
PHD (SAINS BIOPERUBATAN)
UNIVERSITY OF LEEDS
Graduated : 2017
BACELOR SAINS (BIOKIMIA DAN BIOLOGI MOLEKUL)
MIRHIGAN STATE UNIVERSITY
Graduated : 2012
JOURNAL PUBLICATION
1. TRPM2 Channel in Microglia as a New Player in Neuroinflammation Associated With a Spectrum of Central Nervous System Pathologies
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
2. Melastatin-related transient receptor potential 2 channel in Aβ42-induced neuroinflammation: implications to Alzheimer’s disease mechanism and development of therapeutics
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
3. TRPM2 channel-mediated ROS-sensitive Ca2+ signaling mechanisms in immune cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
4. A critical role of TRPM2 channel in Aβ42‐induced microglial activation and generation of tumor necrosis factor‐α
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
5. Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and cell death in microglial cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
6. Carcinoma-specific expression of P2Y11 receptor and its contribution in ATP-induced purinergic signalling and cell migration in human hepatocellular carcinoma cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
7. The TRPM2 channel nexus from oxidative damage to Alzheimer’s pathologies: An emerging novel intervention target for age-related dementia
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
8. ATP-activated P2X7 receptor in the pathophysiology of mood disorders and as an emerging target for the development of novel antidepressant therapeutics
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
9. Predisposition to Alzheimer’s and Age-Related Brain Pathologies by PM2.5 Exposure: Perspective on the Roles of Oxidative Stress and TRPM2 Channel
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
10. Ethanol Induces Microglial Cell Death via the NOX/ROS/PARP/TRPM2 Signalling Pathway
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
11. Signalling Mechanism in TRPM2-dependent Copper- induced HT22 Cell Death
    Journal type: MYCITE
PUBLICATION
2025
The PKC/NOX/ROS and PYK2/MEK/ERK/PARP signalling pathways drive TRPM2 channel activation induced by non-cytolytic oxidative stress in microglial cells
2020
Ethanol Induces Microglial Cell Death via the NOX/ROS/PARP/TRPM2 Signalling Pathway
2020
Predisposition to Alzheimers and Age-Related Brain Pathologies by PM2.5 Exposure: Perspective on the Roles of Oxidative Stress and TRPM2 Channel
2019
TRPM2 Channel in Microglia as a New Player in Neuroinflammation Associated With a Spectrum of Central Nervous System Pathologies
2018
A critical role of TRPM2 channel in A?42?induced microglial activation and generation of tumor necrosis factor??
2018
ATP-activated P2X7 receptor in the pathophysiology of mood disorders and as an emerging target for the development of novel antidepressant therapeutics
2018
Melastatin-related transient receptor potential 2 channel in A?42-induced neuroinflammation: implications to Alzheimers disease mechanism and development of therapeutics
2018
The TRPM2 channel nexus from oxidative damage to Alzheimers pathologies: An emerging novel intervention target for age-related dementia
2017
Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and cell death in microglial cells
2017
Carcinoma-specific expression of P2Y11 receptor and its contribution in ATP-induced purinergic signalling and cell migration in human hepatocellular carcinoma cells
2015
TRPM2 channel-mediated ROS-sensitive Ca2+ signaling mechanisms in immune cells