PROFILE
UPM's Staff Profile
PROF. MADYA DR. NOORJAHAN BANU BINTI MOHAMMED ALITHEEN
ASSOCIATE PROFESSOR
FACULTY OF BIOTECHNOLOGY AND BIOMOLECULAR SCIENCES
noorjahan@upm.edu.my
PROFESSIONAL
NAME :
(Prof. Madya Dr.) NOORJAHAN BANU BINTI MOHAMMED ALITHEEN
POST :
ASSOCIATE PROFESSOR
ENTITY :
FACULTY OF BIOTECHNOLOGY AND BIOMOLECULAR SCIENCES
FIELD OF SUPERVISION
CANCER BIOLOGY AND ONCOLOGY / CELL BIOTECHNOLOGY / IMMUNOPHARMACOLOGY / MEDICAL BIOTECHNOLOGY / ANIMAL BIOTECHNOLOGY
PUBLICATION
2025
Antitumoral and immunoregulatory effects of curcumin analog, (Z)-3-hydroxy-1-(2-hydroxyphenyl)-3-phenyl prop-2-ene-1-one (DK1), on CT26-tumor-bearing BALB/c mice
2024
Anti-Metastasis Effects and Mechanism of Action of Curcumin Analog (2E,6E)-2,6-Bis(2,3-Dimethoxybenzylidene) cyclohexanone (DMCH) on the SW620 Colorectal Cancer Cell Line
2024
Screening of microbial population in Sabah tea kombucha pellicle for its potential as prebiotic and probiotic supplement
2024
Modulatory Effects of Isolated Lactobacillus paracasei from Malaysian Water Kefir Grains on the Intestinal Barrier and Gut Microbiota in Diabetic Mice
2023
Anti?Diabetic Effect of Lactobacillus Paracasei Isolated from Malaysian Water Kefir Grains
2023
A simple and high efficiency purification of His-tagged turnip yellow mosaic virus-like particle (TYMV-VLP) by nickel ion affinity precipitation
2022
Fermented Black Tea and Its Relationship with Gut Microbiota and Obesity: A Mini Review
2022
Expression of Influenza M2e-NP Recombinant Fusion Protein in Escherichia coli BL21 (DE3) and Its Binding to Antibodies
2022
Exosomal-microRNA transcriptome profiling of Parental and CSC-like MDA-MB-231 cells in response to cisplatin treatment
2022
Clinical and Preclinical Studies of Fermented Foods and Their Effects on Alzheimer's Disease
2021
Synergistic Cytotoxicity between Elephantopus scaber and Tamoxifen on MCF-7-Derived Multicellular Tumor Spheroid
2021
Metagenomic and phytochemical analyses of kefir water and its subchronic toxicity study in BALB/c mice
2021
Kefir and Its Biological Activities
2021
Induction of Apoptosis and Regulation of MicroRNA Expres-sion by (2E,6E)-2,6-bis -(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) Treatment on MCF-7 Breast Cancer Cells
2021
Anti- metastatic and Anti-angiogenic Effects of 2 Curcumin Analog DK1 on Human Osteosarcoma 3 Cells In Vitro.
2021
Regulation of cellular and cancer stem cell-related putative gene expression of parental and cd44+ cd24? sorted mda-mb-231 cells by cisplatin
2021
Cytotoxicity and Apoptosis Effects of Curcumin Analogue (2E,6E)-2,6-Bis(2,3-Dimethoxybenzylidine) Cyclohexanone (DMCH) on Human Colon Cancer Cells HT29 and SW620 In Vitro
2021
Selected Kefir Water from Malaysia Attenuates Hydrogen Per-oxide-Induced Oxidative Stress by Upregulating Endogenous Antioxidant Levels in SH-SY5Y Neuroblastoma Cells
2021
Physicochemical characterization, cytotoxic effect and toxicity evaluation of Nanostructured Lipid Carrier loaded with Eucalyptol
2021
M2e-Based Influenza Vaccines with Nucleoprotein: A Review
2020
Antitumor and anti-metastatic effects of citral loaded nanostructured lipid carrier in 4T1 induced breast cancer mouse model
2020
Novel drug delivery systems for loading of natural plant extracts and their biomedical applications
2020
An Overview of In Vitro, In Vivo, and Computational Techniques for Cancer-Associated Angiogenesis Studies
2020
Identifcation of Reference Genes in Chicken Intraepithelial Lymphocyte Natural Killer Cells Infected with Very-virulent Infectious Bursal Disease Virus
2020
Cytotoxicity Study of the Interleukin-12-expressing recombinant Newcastle Disease Virus Strain, rAF-IL12, towards CT26 Colon Cancer Cells in Vitro and in Vivo
2020
Transcriptome Analysis of Chicken Intraepithelial Lymphocyte Natural Killer 2 Cells Infected with Very Virulent Infectious Bursal Disease Virus
2020
Oncolytic Effects of the Recombinant Newcastle Disease Virus, rAF-IL12, against Colon Cancer Cells In Vitro and in Tumor-challenged NCr-Foxn1nu Nude Mice
2020
Eupatorin Suppressed Tumour Progression and Enhanced Immunity in a 4T1 Murine Breast Cancer Model
2019
IN VITRO CYTOTOXICITY AND ANTI CANCER EFFECTS OF CITRAL NANOSTRUCTURED LIPID CARRIER ON MDA MBA-231 HUMAN BREAST CANCER CELLS
2019
Isolation and Identification of Lactobacillus spp. from Kefir Samples in Malaysia
2019
Bromelain Enhances the Anti-Tumor Effects of Cisplatin on 4T1 Breast Tumor Model In Vivo
2019
Anti-inflammatory, analgesic and acute toxicity effects of fermented soybean
2019
In vitro and in vivo anti-tumour effects of coconut water vinegar on 4T1 breast cancer cells
2019
Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells in vitro and in vivo
2019
Cytotoxicity of eupatorin in MCF-7 and MDA-MB-231 human breast cancer cells via cell cycle arrest,anti-angiogenesis and induction of apoptosis
2019
Preparation and Characterization of Self Nano-Emulsifying Drug Delivery System Loaded with Citraland Its Antiproliferative Effect on Colorectal Cells In Vitro
2018
Subchronic toxicity, immunoregulation and anti-breast tumor effect of Nordamnacantal, an anthraquinone extracted from the stems of Morinda citrifolia L.
2018
Coconut Water Vinegar Ameliorates Recovery of Acetaminophen Induced Liver Damage in Mice
2018
Comparison of in vivo toxicity, antioxidant and immunomodulatory activities of coconut, nipah and pineapple juice vinegars
2018
Design, Synthesis and Docking Studies of Flavokawain B Type Chalcones and Their Cytotoxic Effects on MCF-7 and MDA-MB-231 Cell Lines
2018
Design, synthesis and cytotoxic effects of curcuminoids on HeLa, K562, MCF-7 and MDA-MB-231 cancer cell lines
2018
Genetic variation and DNA fingerprinting of durian types in Malaysia using simple sequence repeat (SSR) markers.
2018
Optimization of Illumina TruSeq Targeted RNA Expression (TREx) Library Quality
2018
Facile synthesis of N- (4-bromophenyl)-1- (3-bromothiophen-2-yl)methanimine derivatives via Suzuki cross-coupling reaction: their characterization and DFT studies
2018
DK1 Induces Apoptosis via Mitochondria-Dependent Signaling Pathway in Human Colon Carcinoma Cell LinesIn Vitro
2018
Characterization and toxicity of citral incorporated with nanostructured lipid carrier
2018
Antihyperglycemic and anti-inflammatory effects of fermented food paste on high-fat diet and streptozotocin-challenged mice
2018
Palladium(0) catalyzed Suzuki cross-coupling reaction of 2,5-dibromo-3-methylthiophene: selectivity, characterization, DFT studies and their biological evaluations
2018
Curcumin Analog DK1 Induces Apoptosis in Human Osteosarcoma Cells in Vitro through Mitochondria-Dependent Signaling Pathway
2017
Comparison of in vivo toxicity, antioxidant and immunomodulatory activities of coconut, nipah and pineapple juice vinegars
2017
Synthetic curcumin derivative DK1 possessed G2/M arrest and induced apoptosis through accumulation of intracellular ROS in MCF-7 breast cancer cells
2017
Synthesis and cytotoxic effects of (E)-3-(2,3-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one in MDA-MB231 and MCF-7 breast cancer cell lines
2017
Anti-obesity and anti-inflammatory effects of synthetic acetic acid vinegar and Nipa vinegar on high-fat-diet-induced obese mice
2017
Gene Expression Analysis Reveals the Concurrent Activation of Proapoptotic and Antioxidant-Defensive Mechanisms in Flavokawain B-Treated Cervical Cancer HeLa Cells
2017
Solubility of acyclovir in nontoxic and biodegradable ionic liquids: COSMO-RS prediction and experimental verification
2017
The: In vivo anti-tumor effect of curcumin derivative (2 E,6 E)-2,6-bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone (BHMC) on 4T1 breast cancer cells
2017
Efficient synthesis of novel pyridine-based derivatives via suzuki cross-coupling reaction of commercially available 5-bromo-2-methylpyridin-3-amine: Quantum mechanical investigations and biological activities
2017
Dietary coconut water vinegar for improvement of obesity-associated inflammation in high-fat-diet treated mice
2017
Characterisation of sol-gel method synthesised MgZnFe2O4 nanoparticles and its cytotoxic effects on breast cancer cell line, MDA MB-231
2017
The effects of different velogenic NDV infections on the chicken bursa of Fabricius
2017
RNA sequencing (RNA-Seq) of lymph node, spleen, and thymus transcriptome from wild Peninsular Malaysian cynomolgus macaque (Macaca fascicularis)
2016
Dual Regulation of Cell Death and Cell Survival upon induction of cellular stress by Isopimara-7,15-Dien-19-Oic Acid in cervical cancer, Hela cells In vitro
2016
Gene expression analysis reveals the concurrent activation of proapoptotic and antioxidant-defensive mechanisms in Flavokawain B-treated cervical cancer HeLa cells
2016
Efficient Double Suzuki Cross-Coupling Reactions of 2,5-Dibromo-3-hexylthiophene: Anti-Tumor, Haemolytic, Anti-Thrombolytic and Biofilm Inhibition Studies
2016
Combination of cisplatin and bromelain exerts synergistic cytotoxic effects against breast cancer cell line MDA-MB-231 in vitro
2016
Combinatorial cytotoxic effects of Damnacanthal and Doxorubicin against Human breast cancer MCF-7 cells in vitro
2016
FLAVOKAWAIN B INDUCED CYTOTOXICITY IN TWO BREAST CANCER CELL LINES, MCF-7 AND MDA-MB231 AND INHIBITED THE METASTATIC POTENTIAL OF MDA-MB231VIA THE REGULATION OF SEVERAL TYROSINE KINASES IN VITRO
2016
The Antimetastatic and Antiangiogenesis Effects of Kefir Water on Murine Breast Cancer Cells
2015
Comparison of free amino acids, antioxidants, soluble phenolic acids, cytotoxicity and immunomodulation of fermented mung bean and soybean
2015
Antistress and antioxidant effects of virgin coconut oil in vivo
2015
Nordamnacanthal potentiates the cytotoxic effects of tamoxifen in human breast cancer cells
2015
Rapid growth and osteogenic differentiation of mesenchymal stem cells isolated from human bone marrow
2015
In vivo Anti-Tumor And Anti-Metastatic Effects of Flavokawain B in 4T1 Breast Cancer Cell-Challenged Mice
2015
In vivo antitumor and antimetastatic effects of flavokawain B in 4T1 breast cancer cell-challenged mice
2015
Antioxidant effects of pineapple vinegar in reversing of paracetamol-induced liver damage in mice
2015
Effect of imidazolium-based ionic liquids on bacterial growth inhibition investigated via experimental and QSAR modelling studies
2015
Synthesis of anthraquinone derivative (DHAQC) and its effect on induction of G2/M arrest and apoptosis in breast cancer MCF-7 cell lines
2015
Chemopreventive and immunomodulatory effects of Murraya koenigii aqueous extract on 4T1 breast cancer cell-challenged mice
2015
In vitro Toxicity and in vivo Immunomodulatory Effects of Flavokawain A and Flavokawain B in Balb/C Mice
2015
In vitro antioxidant and in vivo hepatoprotective effect on Ethanol mediated liver damage of spray dried Vernonia amygdalina water extract
2015
In Vivo Antioxidant and Hypolipidemic Effects of Fermented Mung Bean on Hypercholesterolemic Mice
2015
Cellular crosstalk mechanism of Toll-like receptors in gingival overgrowth (Review)
2015
Neural differentiation of human umbilical cord matrix-derived mesenchymal cells under special culture conditions
2014
Immunomodulatory Effect of Newcastle Disease Virus AF2240 Strain on Human Peripheral Blood Mononuclear Cells
2014
In Vivo Antistress and Antioxidant Effects of Fermented and Germinated Mung Bean
2014
In vitro antioxidant and In vivo hepatoprotective effect on Ethanol-mediated liver damage of spray dried Vernonia amygdalina water extract
2014
Angiotensin II stimuklates expression of transcription factors c-Jun and c-Fos in cyclosporine induced human gingival fibroblasts
2014
Damnacanthal: A Promising Compound as a Medicinal Anthraquinone
2014
Immunomodulatory effects of Potentilla indica and Dendrophthoe pentandra on mice splenocytes and thymocytes
2014
Vitamin C suppresses cell death in MCF-7 human breast cancer cells induced by tamoxifen
2014
Flavokawain A induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro
2014
Anti-inflammatory and Antinociceptive activities of untreated, germinated and fermented mung bean aqueous extract
2014
In Vivo Hypocholesterolemic Effect of MARDI Fermented Red Yeast Rice Water Extract in High Cholesterol Diet Fed Mice
2014
Damnacanthal is a potent inducer of apoptosis with anticancer activity by stimulating p53 and p21 genes in MCF-7 breast cancer cells
2013
The flavokawains: uprising medicinal chalcones
2013
Antioxidant and hepatoprotective effect of aqueous extract of Germinated and Fermented Mung Bean on Ethanol-Mediated Liver Damage
2013
Effect of EGF and FGF on the expansion properties of human umbilical cord mesenchymal cells
2013
Goniothalamin selectively induces apoptosis on human hepatoblastoma cells through caspase-3 activation
2013
Construction of single-chain variable fragment antibodies against MCF-7 breast cancer cells
2013
In vivo antidiabetic and acute toxicity of spray-dried Vernonia amygdalina water extract
2013
In Vivo Immunomodulation and Lipid Peroxidation Activities Contributed to Chemoprevention Effects of Fermented Mung Bean against Breast Cancer
2013
Hepatoprotective Effect of Fermented Soybean (Nutrient Enriched Soybean Tempeh) against Alcohol-Induced Liver Damage in Mice
2013
Total synthesis, cytotoxic effects of damnacanthal, nordamnacanthal and related anthraquinone analogues
2013
Rhaphidophora korthalsii modulates peripheral blood natural killer cell proliferation, cytokine secretion and cytotoxicity
2013
The Possible Potential Therapeutic Targets for Drug Induced Gingival Overgrowth
2013
3-Bromo-1-Hydroxy-9,10-Anthraquinone (BHAQ)Inhibits Growth and Migration of the Human Breast Cancer Cell Lines MCF-7 and MDA-MB231
2013
Influence of mast cells in drug-induced gingival overgrowth
2013
Synthesis and anti-microbial potencies of 1-(2-hydroxyethyl) -3-alkylimidazolium chloride ionic liquids: Microbial viabilities at different ionic liquids concentrations
2012
Comparison of different methods for the isolation of mesenchymal stem cells from human umbilical cord Wharton?s jelly
2012
scFv Antibody: Principles and Clinical Application
2012
In vitro and in vivo toxicity of Garcinia or Hydroxycitric acid: A Review
2012
Development of multicellular tumor spheroid (MCTS) culture from breast cancer cell and a high throughput screening method using the MTT assay
2012
Establishment of an in vitro system representing the chicken gut-associated lymphoid tissue
2012
Immunomodulatory Effects of Betulinic Acid Isolation from the Bark of Melaleuca cajuputi
2012
A review of risk factors, incidence and solutions for hepatocellular carcinoma
2012
Betulinic Acid inhibits growth of cultured vascular smooth muscle cells in vitro by inducing G1 arrest and apoptosis
2012
Bioactivity studies and chemical constituents of Murraya paniculata (Linn) Jack
2012
Effect of culture media on expansion properties of human umbilical cord matrix-derived mesenchymal cells
2012
Construction of Single-Chain Variable Fragment (scFv) Antibodies against MCF-7 Breast Cancer Cells
2012
Immunomodulatory Effect of Rhaphidophora korthalsii on Natural Killer Cell Cytotoxicity
2012
Hepatoprotective Activity of Elephantopus scaber on Alcohol-induced Liver Damage in Mice
2012
In vitro and in vivo antioxidant activity of Vernonia amygdalina water extract
2012
Antihyperglycemic Effects of Fermented and Nonfermented Mung Bean Extracts on Alloxan-Induced-Diabetic Mice
2011
CYTOTOXIC EFFECTS OF COMMERCIAL WHEATGRASS AND FIBER TOWARDS HUMAN ACUTE PROMYELOCYTIC LEUKEMIA CELLS (HL60)
2011
Immunomodulatory role of Rhaphidophora korthalsii methanol extract on human peripheral blood mononuclear cell proliferation, cytokine secretion and cytolytic activity
2011
Safety and Clinical Usage of Newcastle Disease Virus in Cancer Therapy
2011
Elephantopus scaber induces cytotoxicity in MCF-7 human breast cancer cells via p53-induced apoptosis
2011
Selective Cytotoxicity of Goniothalamin against Hepatoblastoma HepG2 Cells
2011
Immunomodulatory effect of Rhaphidophora korthalsii on mice splenocyte, thymocyte and bone marrow cell proliferation and cytokine expression
2011
Evaluation of Immunomodulatory Effect:Selection of the Correct Targets for Immunostimulation Study
2010
Cytotoxic effect of betulinic acid acetate isolated from Melaleuca cajuput on human myeloid leukemia (HL-60) cell line
2010
Immunomodulatory Effects of Damnacanthal Isolated from Roots of Morinda elliptica (Rubiceae)
2010
Understand the Role of Natural Killer
2010
Cytotoxic Effect of Damnacanthal, Nordamnacanthal, Zerumbone and Betulinic Acid Isolated from Malaysian Plant Sources
2010
Immunomodulatory Effects of Zerumbone Isolated From Roots of Zingiber Zerumbet
2010
B-cell development: one problem, multiple solutions.
2009
A mouse IgM monoclonal antibody recognized breast and colon cancer.
2009
Review :Traditional practice, bioactivities and commercialization potential of Elephantopus scaber Linn
2009
Identification of Vibrio parahaemolyticus isolates by PCR targeted to the toxR
2009
Traditional practice, bioactivities and commercialization potential of Elephantopus scaber Linn.
2009
Antibiotic resistance and plasmid profiling of Vibrio parahaemolyticus
2009
Random amplified polymorphic DNA-PCR and ERIC PCR analysis on Vibrio parahaemolyticus isolated from cockles in Padang, Indonesia
2009
Cytotoxic effect of 2?, 3?-epoxy isocapnolactone and 8-hydroxyisocapnolactone-2?3?-diol isolated from Micromelum minutum (G.Forst.) Wight and Arn. in human T-lymphocyte leukemia CEM-SS cells