PROFILE
UPM's Staff Profile
PROF. MADYA DR. NOORJAHAN BANU BINTI MOHAMMED ALITHEEN
ASSOCIATE PROFESSOR
FACULTY OF BIOTECHNOLOGY AND BIOMOLECULAR SCIENCES
noorjahan@upm.edu.my
PROFESSIONAL
NAME:
(PROF. MADYA DR.) NOORJAHAN BANU BINTI MOHAMMED ALITHEEN
POSITION:
ASSOCIATE PROFESSOR
ENTITY:
FACULTY OF BIOTECHNOLOGY AND BIOMOLECULAR SCIENCES
FIELDS OF SUPERVISION
Cancer Biology And Oncology / Cell Biotechnology / Immunopharmacology / Medical Biotechnology / Animal Biotechnology
PUBLICATION
2025:
Antitumoral and immunoregulatory effects of curcumin analog, (Z)-3-hydroxy-1-(2-hydroxyphenyl)-3-phenyl prop-2-ene-1-one (DK1), on CT26-tumor-bearing BALB/c mice
2024:
Anti-Metastasis Effects and Mechanism of Action of Curcumin Analog (2E,6E)-2,6-Bis(2,3-Dimethoxybenzylidene) cyclohexanone (DMCH) on the SW620 Colorectal Cancer Cell Line
2024:
Screening of microbial population in Sabah tea kombucha pellicle for its potential as prebiotic and probiotic supplement
2024:
Modulatory Effects of Isolated Lactobacillus paracasei from Malaysian Water Kefir Grains on the Intestinal Barrier and Gut Microbiota in Diabetic Mice
2023:
Anti?Diabetic Effect of Lactobacillus Paracasei Isolated from Malaysian Water Kefir Grains
2023:
A simple and high efficiency purification of His-tagged turnip yellow mosaic virus-like particle (TYMV-VLP) by nickel ion affinity precipitation
2022:
Fermented Black Tea and Its Relationship with Gut Microbiota and Obesity: A Mini Review
2022:
Expression of Influenza M2e-NP Recombinant Fusion Protein in Escherichia coli BL21 (DE3) and Its Binding to Antibodies
2022:
Exosomal-microRNA transcriptome profiling of Parental and CSC-like MDA-MB-231 cells in response to cisplatin treatment
2022:
Clinical and Preclinical Studies of Fermented Foods and Their Effects on Alzheimer's Disease
2021:
Synergistic Cytotoxicity between Elephantopus scaber and Tamoxifen on MCF-7-Derived Multicellular Tumor Spheroid
2021:
Metagenomic and phytochemical analyses of kefir water and its subchronic toxicity study in BALB/c mice
2021:
Kefir and Its Biological Activities
2021:
Induction of Apoptosis and Regulation of MicroRNA Expres-sion by (2E,6E)-2,6-bis -(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) Treatment on MCF-7 Breast Cancer Cells
2021:
Anti- metastatic and Anti-angiogenic Effects of 2 Curcumin Analog DK1 on Human Osteosarcoma 3 Cells In Vitro.
2021:
Regulation of cellular and cancer stem cell-related putative gene expression of parental and cd44+ cd24? sorted mda-mb-231 cells by cisplatin
2021:
Cytotoxicity and Apoptosis Effects of Curcumin Analogue (2E,6E)-2,6-Bis(2,3-Dimethoxybenzylidine) Cyclohexanone (DMCH) on Human Colon Cancer Cells HT29 and SW620 In Vitro
2021:
Selected Kefir Water from Malaysia Attenuates Hydrogen Per-oxide-Induced Oxidative Stress by Upregulating Endogenous Antioxidant Levels in SH-SY5Y Neuroblastoma Cells
2021:
Physicochemical characterization, cytotoxic effect and toxicity evaluation of Nanostructured Lipid Carrier loaded with Eucalyptol
2021:
M2e-Based Influenza Vaccines with Nucleoprotein: A Review
2020:
Antitumor and anti-metastatic effects of citral loaded nanostructured lipid carrier in 4T1 induced breast cancer mouse model
2020:
Novel drug delivery systems for loading of natural plant extracts and their biomedical applications
2020:
An Overview of In Vitro, In Vivo, and Computational Techniques for Cancer-Associated Angiogenesis Studies
2020:
Identifcation of Reference Genes in Chicken Intraepithelial Lymphocyte Natural Killer Cells Infected with Very-virulent Infectious Bursal Disease Virus
2020:
Cytotoxicity Study of the Interleukin-12-expressing recombinant Newcastle Disease Virus Strain, rAF-IL12, towards CT26 Colon Cancer Cells in Vitro and in Vivo
2020:
Transcriptome Analysis of Chicken Intraepithelial Lymphocyte Natural Killer 2 Cells Infected with Very Virulent Infectious Bursal Disease Virus
2020:
Oncolytic Effects of the Recombinant Newcastle Disease Virus, rAF-IL12, against Colon Cancer Cells In Vitro and in Tumor-challenged NCr-Foxn1nu Nude Mice
2020:
Eupatorin Suppressed Tumour Progression and Enhanced Immunity in a 4T1 Murine Breast Cancer Model
2019:
IN VITRO CYTOTOXICITY AND ANTI CANCER EFFECTS OF CITRAL NANOSTRUCTURED LIPID CARRIER ON MDA MBA-231 HUMAN BREAST CANCER CELLS
2019:
Isolation and Identification of Lactobacillus spp. from Kefir Samples in Malaysia
2019:
Bromelain Enhances the Anti-Tumor Effects of Cisplatin on 4T1 Breast Tumor Model In Vivo
2019:
Anti-inflammatory, analgesic and acute toxicity effects of fermented soybean
2019:
In vitro and in vivo anti-tumour effects of coconut water vinegar on 4T1 breast cancer cells
2019:
Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells in vitro and in vivo
2019:
Cytotoxicity of eupatorin in MCF-7 and MDA-MB-231 human breast cancer cells via cell cycle arrest,anti-angiogenesis and induction of apoptosis
2019:
Preparation and Characterization of Self Nano-Emulsifying Drug Delivery System Loaded with Citraland Its Antiproliferative Effect on Colorectal Cells In Vitro
2018:
Subchronic toxicity, immunoregulation and anti-breast tumor effect of Nordamnacantal, an anthraquinone extracted from the stems of Morinda citrifolia L.
2018:
Coconut Water Vinegar Ameliorates Recovery of Acetaminophen Induced Liver Damage in Mice
2018:
Comparison of in vivo toxicity, antioxidant and immunomodulatory activities of coconut, nipah and pineapple juice vinegars
2018:
Design, Synthesis and Docking Studies of Flavokawain B Type Chalcones and Their Cytotoxic Effects on MCF-7 and MDA-MB-231 Cell Lines
2018:
Design, synthesis and cytotoxic effects of curcuminoids on HeLa, K562, MCF-7 and MDA-MB-231 cancer cell lines
2018:
Genetic variation and DNA fingerprinting of durian types in Malaysia using simple sequence repeat (SSR) markers.
2018:
Optimization of Illumina TruSeq Targeted RNA Expression (TREx) Library Quality
2018:
Facile synthesis of N- (4-bromophenyl)-1- (3-bromothiophen-2-yl)methanimine derivatives via Suzuki cross-coupling reaction: their characterization and DFT studies
2018:
DK1 Induces Apoptosis via Mitochondria-Dependent Signaling Pathway in Human Colon Carcinoma Cell LinesIn Vitro
2018:
Characterization and toxicity of citral incorporated with nanostructured lipid carrier
2018:
Antihyperglycemic and anti-inflammatory effects of fermented food paste on high-fat diet and streptozotocin-challenged mice
2018:
Palladium(0) catalyzed Suzuki cross-coupling reaction of 2,5-dibromo-3-methylthiophene: selectivity, characterization, DFT studies and their biological evaluations
2018:
Curcumin Analog DK1 Induces Apoptosis in Human Osteosarcoma Cells in Vitro through Mitochondria-Dependent Signaling Pathway
2017:
Comparison of in vivo toxicity, antioxidant and immunomodulatory activities of coconut, nipah and pineapple juice vinegars
2017:
Synthetic curcumin derivative DK1 possessed G2/M arrest and induced apoptosis through accumulation of intracellular ROS in MCF-7 breast cancer cells
2017:
Synthesis and cytotoxic effects of (E)-3-(2,3-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one in MDA-MB231 and MCF-7 breast cancer cell lines
2017:
Anti-obesity and anti-inflammatory effects of synthetic acetic acid vinegar and Nipa vinegar on high-fat-diet-induced obese mice
2017:
Gene Expression Analysis Reveals the Concurrent Activation of Proapoptotic and Antioxidant-Defensive Mechanisms in Flavokawain B-Treated Cervical Cancer HeLa Cells
2017:
Solubility of acyclovir in nontoxic and biodegradable ionic liquids: COSMO-RS prediction and experimental verification
2017:
The: In vivo anti-tumor effect of curcumin derivative (2 E,6 E)-2,6-bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone (BHMC) on 4T1 breast cancer cells
2017:
Efficient synthesis of novel pyridine-based derivatives via suzuki cross-coupling reaction of commercially available 5-bromo-2-methylpyridin-3-amine: Quantum mechanical investigations and biological activities
2017:
Dietary coconut water vinegar for improvement of obesity-associated inflammation in high-fat-diet treated mice
2017:
Characterisation of sol-gel method synthesised MgZnFe2O4 nanoparticles and its cytotoxic effects on breast cancer cell line, MDA MB-231
2017:
The effects of different velogenic NDV infections on the chicken bursa of Fabricius
2017:
RNA sequencing (RNA-Seq) of lymph node, spleen, and thymus transcriptome from wild Peninsular Malaysian cynomolgus macaque (Macaca fascicularis)
2016:
Dual Regulation of Cell Death and Cell Survival upon induction of cellular stress by Isopimara-7,15-Dien-19-Oic Acid in cervical cancer, Hela cells In vitro
2016:
Gene expression analysis reveals the concurrent activation of proapoptotic and antioxidant-defensive mechanisms in Flavokawain B-treated cervical cancer HeLa cells
2016:
Efficient Double Suzuki Cross-Coupling Reactions of 2,5-Dibromo-3-hexylthiophene: Anti-Tumor, Haemolytic, Anti-Thrombolytic and Biofilm Inhibition Studies
2016:
Combination of cisplatin and bromelain exerts synergistic cytotoxic effects against breast cancer cell line MDA-MB-231 in vitro
2016:
Combinatorial cytotoxic effects of Damnacanthal and Doxorubicin against Human breast cancer MCF-7 cells in vitro
2016:
FLAVOKAWAIN B INDUCED CYTOTOXICITY IN TWO BREAST CANCER CELL LINES, MCF-7 AND MDA-MB231 AND INHIBITED THE METASTATIC POTENTIAL OF MDA-MB231VIA THE REGULATION OF SEVERAL TYROSINE KINASES IN VITRO
2016:
The Antimetastatic and Antiangiogenesis Effects of Kefir Water on Murine Breast Cancer Cells
2015:
Comparison of free amino acids, antioxidants, soluble phenolic acids, cytotoxicity and immunomodulation of fermented mung bean and soybean
2015:
Antistress and antioxidant effects of virgin coconut oil in vivo
2015:
Nordamnacanthal potentiates the cytotoxic effects of tamoxifen in human breast cancer cells
2015:
Rapid growth and osteogenic differentiation of mesenchymal stem cells isolated from human bone marrow
2015:
In vivo Anti-Tumor And Anti-Metastatic Effects of Flavokawain B in 4T1 Breast Cancer Cell-Challenged Mice
2015:
In vivo antitumor and antimetastatic effects of flavokawain B in 4T1 breast cancer cell-challenged mice
2015:
Antioxidant effects of pineapple vinegar in reversing of paracetamol-induced liver damage in mice
2015:
Effect of imidazolium-based ionic liquids on bacterial growth inhibition investigated via experimental and QSAR modelling studies
2015:
Synthesis of anthraquinone derivative (DHAQC) and its effect on induction of G2/M arrest and apoptosis in breast cancer MCF-7 cell lines
2015:
Chemopreventive and immunomodulatory effects of Murraya koenigii aqueous extract on 4T1 breast cancer cell-challenged mice
2015:
In vitro Toxicity and in vivo Immunomodulatory Effects of Flavokawain A and Flavokawain B in Balb/C Mice
2015:
In vitro antioxidant and in vivo hepatoprotective effect on Ethanol mediated liver damage of spray dried Vernonia amygdalina water extract
2015:
In Vivo Antioxidant and Hypolipidemic Effects of Fermented Mung Bean on Hypercholesterolemic Mice
2015:
Cellular crosstalk mechanism of Toll-like receptors in gingival overgrowth (Review)
2015:
Neural differentiation of human umbilical cord matrix-derived mesenchymal cells under special culture conditions
2014:
Immunomodulatory Effect of Newcastle Disease Virus AF2240 Strain on Human Peripheral Blood Mononuclear Cells
2014:
In Vivo Antistress and Antioxidant Effects of Fermented and Germinated Mung Bean
2014:
In vitro antioxidant and In vivo hepatoprotective effect on Ethanol-mediated liver damage of spray dried Vernonia amygdalina water extract
2014:
Angiotensin II stimuklates expression of transcription factors c-Jun and c-Fos in cyclosporine induced human gingival fibroblasts
2014:
Damnacanthal: A Promising Compound as a Medicinal Anthraquinone
2014:
Immunomodulatory effects of Potentilla indica and Dendrophthoe pentandra on mice splenocytes and thymocytes
2014:
Vitamin C suppresses cell death in MCF-7 human breast cancer cells induced by tamoxifen
2014:
Flavokawain A induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro
2014:
Anti-inflammatory and Antinociceptive activities of untreated, germinated and fermented mung bean aqueous extract
2014:
In Vivo Hypocholesterolemic Effect of MARDI Fermented Red Yeast Rice Water Extract in High Cholesterol Diet Fed Mice
2014:
Damnacanthal is a potent inducer of apoptosis with anticancer activity by stimulating p53 and p21 genes in MCF-7 breast cancer cells
2013:
The flavokawains: uprising medicinal chalcones
2013:
Antioxidant and hepatoprotective effect of aqueous extract of Germinated and Fermented Mung Bean on Ethanol-Mediated Liver Damage
2013:
Effect of EGF and FGF on the expansion properties of human umbilical cord mesenchymal cells
2013:
Goniothalamin selectively induces apoptosis on human hepatoblastoma cells through caspase-3 activation
2013:
Construction of single-chain variable fragment antibodies against MCF-7 breast cancer cells
2013:
In vivo antidiabetic and acute toxicity of spray-dried Vernonia amygdalina water extract
2013:
In Vivo Immunomodulation and Lipid Peroxidation Activities Contributed to Chemoprevention Effects of Fermented Mung Bean against Breast Cancer
2013:
Hepatoprotective Effect of Fermented Soybean (Nutrient Enriched Soybean Tempeh) against Alcohol-Induced Liver Damage in Mice
2013:
Total synthesis, cytotoxic effects of damnacanthal, nordamnacanthal and related anthraquinone analogues
2013:
Rhaphidophora korthalsii modulates peripheral blood natural killer cell proliferation, cytokine secretion and cytotoxicity
2013:
The Possible Potential Therapeutic Targets for Drug Induced Gingival Overgrowth
2013:
3-Bromo-1-Hydroxy-9,10-Anthraquinone (BHAQ)Inhibits Growth and Migration of the Human Breast Cancer Cell Lines MCF-7 and MDA-MB231
2013:
Influence of mast cells in drug-induced gingival overgrowth
2013:
Synthesis and anti-microbial potencies of 1-(2-hydroxyethyl) -3-alkylimidazolium chloride ionic liquids: Microbial viabilities at different ionic liquids concentrations
2012:
Comparison of different methods for the isolation of mesenchymal stem cells from human umbilical cord Wharton?s jelly
2012:
ScFv Antibody: Principles and Clinical Application
2012:
In vitro and in vivo toxicity of Garcinia or Hydroxycitric acid: A Review
2012:
Development of multicellular tumor spheroid (MCTS) culture from breast cancer cell and a high throughput screening method using the MTT assay
2012:
Establishment of an in vitro system representing the chicken gut-associated lymphoid tissue
2012:
Immunomodulatory Effects of Betulinic Acid Isolation from the Bark of Melaleuca cajuputi
2012:
A review of risk factors, incidence and solutions for hepatocellular carcinoma
2012:
Betulinic Acid inhibits growth of cultured vascular smooth muscle cells in vitro by inducing G1 arrest and apoptosis
2012:
Bioactivity studies and chemical constituents of Murraya paniculata (Linn) Jack
2012:
Effect of culture media on expansion properties of human umbilical cord matrix-derived mesenchymal cells
2012:
Construction of Single-Chain Variable Fragment (scFv) Antibodies against MCF-7 Breast Cancer Cells
2012:
Immunomodulatory Effect of Rhaphidophora korthalsii on Natural Killer Cell Cytotoxicity
2012:
Hepatoprotective Activity of Elephantopus scaber on Alcohol-induced Liver Damage in Mice
2012:
In vitro and in vivo antioxidant activity of Vernonia amygdalina water extract
2012:
Antihyperglycemic Effects of Fermented and Nonfermented Mung Bean Extracts on Alloxan-Induced-Diabetic Mice
2011:
CYTOTOXIC EFFECTS OF COMMERCIAL WHEATGRASS AND FIBER TOWARDS HUMAN ACUTE PROMYELOCYTIC LEUKEMIA CELLS (HL60)
2011:
Immunomodulatory role of Rhaphidophora korthalsii methanol extract on human peripheral blood mononuclear cell proliferation, cytokine secretion and cytolytic activity
2011:
Safety and Clinical Usage of Newcastle Disease Virus in Cancer Therapy
2011:
Elephantopus scaber induces cytotoxicity in MCF-7 human breast cancer cells via p53-induced apoptosis
2011:
Selective Cytotoxicity of Goniothalamin against Hepatoblastoma HepG2 Cells
2011:
Immunomodulatory effect of Rhaphidophora korthalsii on mice splenocyte, thymocyte and bone marrow cell proliferation and cytokine expression
2011:
Evaluation of Immunomodulatory Effect:Selection of the Correct Targets for Immunostimulation Study
2010:
Cytotoxic effect of betulinic acid acetate isolated from Melaleuca cajuput on human myeloid leukemia (HL-60) cell line
2010:
Immunomodulatory Effects of Damnacanthal Isolated from Roots of Morinda elliptica (Rubiceae)
2010:
Understand the Role of Natural Killer
2010:
Cytotoxic Effect of Damnacanthal, Nordamnacanthal, Zerumbone and Betulinic Acid Isolated from Malaysian Plant Sources
2010:
Immunomodulatory Effects of Zerumbone Isolated From Roots of Zingiber Zerumbet
2010:
B-cell development: one problem, multiple solutions.
2009:
A mouse IgM monoclonal antibody recognized breast and colon cancer.
2009:
Review :Traditional practice, bioactivities and commercialization potential of Elephantopus scaber Linn
2009:
Identification of Vibrio parahaemolyticus isolates by PCR targeted to the toxR
2009:
Traditional practice, bioactivities and commercialization potential of Elephantopus scaber Linn.
2009:
Antibiotic resistance and plasmid profiling of Vibrio parahaemolyticus
2009:
Random amplified polymorphic DNA-PCR and ERIC PCR analysis on Vibrio parahaemolyticus isolated from cockles in Padang, Indonesia
2009:
Cytotoxic effect of 2?, 3?-epoxy isocapnolactone and 8-hydroxyisocapnolactone-2?3?-diol isolated from Micromelum minutum (G.Forst.) Wight and Arn. in human T-lymphocyte leukemia CEM-SS cells