A
PROFILE
UPM's Staff Profile
YBHG. PROFESOR DR. MUHAMMAD NAZRUL HAKIM BIN ABDULLAH
PROFESSOR
FACULTY OF MEDICINE AND HEALTH SCIENCES
nazrulh@upm.edu.my
UPM WEBSITE
PROFILE
nazrulh
BM
EN

PROFESSIONAL

NAME :
(Ybhg. Profesor Dr.) MUHAMMAD NAZRUL HAKIM BIN ABDULLAH
POST :
PROFESSOR
ENTITY :
FACULTY OF MEDICINE AND HEALTH SCIENCES

FIELD OF SUPERVISION
PHARMACOLOGY / TOXICOLOGY
EDUCATION
PHD
UNIVERSITY OF LONDON, LONDON, UNITED KINGDOM
Graduated : 1998
BACELOR (DOCTOR OF VETERINARY MEDICINE)
UNIVERSITI PERTANIAN MALAYSIA, SERDANG, SELANGOR
Graduated : 1994
BOOK PUBLICATION
JOURNAL PUBLICATION
1. Selective In vitro Cytotoxic Effects of Piroxicam and Mefenamic Acid on Several Cancer Cell Lines
    Journal type: Other Abstracting / Indexing Bodies
2. In vitro anti-fungal and anti-bacterial activity of Drymoglossum piloselloides L. Presl. against several fungi responsible for Athlete?s foot and common pathogenic bacteria
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
3. ANTI- INFLAMMATORY EFFECTS OF HIBISCUS ROSA-SINENSIS L. AND Hibiscus ROSA-SINENSIS VAR. ALBA ETHANOL EXTRACTS
    Journal type: Citation-Indexed - Scopus
4. ENHANCED ANTI-INFLAMMATORY EFFECTS OF NANOENCAPSULATED DICLOFENAC
    Journal type: Citation-Indexed - Scopus
5. Rapid spectrophotometric determination, characterization and anti-inflammatory efficacy evaluation of nanoencapsulated diclofenac sodium
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
6. Barrier protective effects of Asiatic acid in TNF-alpha induced activation of human aortic endothelial cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
7. Supression of Histamine induced permeability of endothelium via nicric oxide
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
8. Physical Evaluation of Selected Malaysian National Rugby Players
    Journal type: Citation-Indexed - Scopus
9. Anti-fungal activity of Ardisia crispa against several fungi responsible for athlete?s foot
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
10. Preliminary Toxicological Evaluations of Polypeptide-K Isolated from Momordica Charantia in Laboratory Rats
    Journal type: Other Abstracting / Indexing Bodies
11. Improved Blood Glucose Level Associated With Polypeptide-K (Diabegard), A Polypeptide Isolated from the Seeds of Momordica charantia Supplementation: Evaluation of 6 Cases
    Journal type: Citation-Indexed - Scopus
12. EFFECTS OF CENTELLAASIATICA L., CURCUMA LONGA L., AND STROBILANTHESCRISPUS L. EXTRACTS ON 3 KIDNEY CELL LINES: IN VITRO CYTOTOXICITY ANALYSIS
    Journal type: Citation-Indexed - Scopus
13. A Report of Six Clinical Cases of Lowered Blood Cholesterol Profile Associated with Supplementation with Polypeptide K (Diabegard), a Polypeptide Isolated from the Seeds of Momordica charantia Linn
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
14. Relationship between Body Fat Percent and Maximal Oxygen Uptake among Young Adults
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
15. Disruptive Mechanisms of interferon gamma in endothelial barrier function
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
16. In vitro antimicrobial activity of leaves of Acalypha indica Linn. (Euphorbiaceae)
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
17. Diuretic properties of Orthosiphon stamineus Benth
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
18. The effect of Creatine Monohydrate Supplement on the body composition, among young adults
    Journal type: Other Abstracting / Indexing Bodies
19. IN VITRO ANTI-VIRAL ACTIVITY OF CENTELLA ASIATICA L., CURCUMA LONGAL. AND STROBILANTHES CRISPUS L. AGAINST HERPES VIRUS.
    Journal type: Citation-Indexed - Scopus
20. Selective In vitro citotoxicity effects of piroxicam and mefenamic acid on several cancer cell lines
    Journal type: Non Citation-Indexed
21. Development and characterisation study of liposomes-encapsulated piroxicam
    Journal type: Other Abstracting / Indexing Bodies
22. Diuretic Activity of Roots from Carica papaya L. and Ananas comous L.
    Journal type: Citation-Indexed - Scopus
23. Persistent Organic Chemicals in Malaysian Waters: A review
    Journal type: Other Abstracting / Indexing Bodies
24. Effects of polypeptide-k supplemented soft bun on blood glucose level in healthy adults
    Journal type: Other Abstracting / Indexing Bodies
25. Subacute effects of edible film from modified sago starch in rats
    Journal type: Citation-Indexed - Scopus
26. Cytoprotective and enhanced anti-inflammatory activities of liposomal piroxicam formulation in lipopolysaccharide-stimulated RAW 264.7 macrophages
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
27. Liposome Encapsulation: A Promising Approach to Enhanced and Safe Mefenamic acid Therapy
    Journal type: Other Abstracting / Indexing Bodies
28. A Comprehensive Review on Cosmos caudatus (Ulam Raja) : Pharmacology, Ethnopharmacology, and Phytochemistry
    Journal type: Other Abstracting / Indexing Bodies
29. Experimental Review on t he Substance P - Enhanced Endothelial P ermeability i n Human Umbilical Vein Endothelial Cells (HUVECS)
    Journal type: Other Abstracting / Indexing Bodies
30. Nitric Oxide Production b y Substance P Induced - Murine Raw 264.7 Macrophages
    Journal type: Other Abstracting / Indexing Bodies
31. The effect of exergaming on knee proprioception in older men: A randomized controlled trial
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
32. Cosmos caudatus extract/fractions reduce smooth muscle cells migration and invasion in vitro: A potential benefit of suppressing atherosclerosis
    Journal type: Other Abstracting / Indexing Bodies
33. Comparative ultrastructural hepatic alterations induced by free and liposome-encapsulated mefenamic acid
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
34. In vitro characterization and in vivo performance of mefenamic acid-sodium diethyldithiocarbamate based liposomes
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
35. Renal ultrastructural alterations induced byvarious preparations of mefenamic acid
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
36. Effects of 4 Thiopurine Compounds on Nitric Oxide Production and Cell Viability of HIG-82 Synoviocytes and RAW 264.7 Macrophages
    Journal type: Citation-Indexed - Scopus
37. Patient experiences during patient education on Anterior Cruciate Ligament Reconstruction (ACLR) rehabilitation using face-to-face interactions with physiotherapists
    Journal type: Non Citation-Indexed
38. In vitro cytotoxic potential of 3 propionic acid derivatives to normal and cancer liver cell lines
    Journal type: Citation-Indexed - Scopus
39. A Comparison between Metformin Immediate-release and Extended-release: A Review
    Journal type: Citation-Indexed - Scopus
40. Interferon-gamma (IFN-γ): Reviewing its mechanisms and signaling pathways on the regulation of endothelial barrier function
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
41. Metformin Immediate and Extended-Release Adverse Events and Effects on Metabolic Parameters: A Meta-Analysis
    Journal type: Citation-Indexed Journal - ESCI
42. Effect of Carcinomas on Autosomal Trait Screening: A Review Article
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
43. Comparison of Cytotoxicity Effects of Propionic Acid Compounds to THLE-2 and HEP-G2 Cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
44. Medicinal plants from Southeast Asia affecting the reproductive system
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
45. STR profiling in a cohort of Saudi patients with acute leukemia
    Journal type: Citation-Indexed - Scopus
46. Endothelial barrier disruptive effect of IFN-Ƴ and TNF-α: Synergism of pro-inflammatory cytokines
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
PUBLICATION
2025
Medicinal plants from Southeast Asia affecting the reproductive system
2025
Analyzing NSAIDS research trends: A six-year bibliometric study (2018-2023) on directions, themes, and dimensions
2025
Phytochemical Profiling and Anti-Inflammatory Activity of Leaf Extract from Cleome gynandra Linn. and Melicope ptelefolia Champ. ex Benth
2025
STR profiling in a cohort of Saudi patients with acute leukemia
2025
Anti-Proliferative Activity of [Cu(phen)(D-threo)]NO? + F? Against Colorectal and Ovarian Cancer Cell Lines
2025
Endothelial barrier disruptive effect of IFN-? and TNF-?: Synergism of pro-inflammatory cytokines
2025
ANTI-PROLIFERATIVE EFFECTS OF CU(PHEN)(C-DIMETHYLGLYCINE)NO3 ON HT-29 AND A2780 CANCER CELL LINES: A POTENTIAL CHEMOTHERAPEUTIC APPROACH
2025
Non-steroidal anti-inflammatory drug-induced gastric ulcers: A review on some current issues
2024
Luteolin Suppresses Endothelial Permeability and Nitric Oxide Scavenging Effects
2024
Improved Anti-nociceptive, Anti-pyretic and Anti-inflammatory Effects of Orally Administered Liposome-encapsulated Piroxicam
2024
Comparison of Cytotoxicity Effects of Propionic Acid Compounds to THLE-2 and HEP-G2 Cells
2024
Prevention of Atherogenesis by Channa Striatus Fish Extract in an Experimental Model of Atherosclerosis
2024
Effects of 6-mercaptopurine and its derivatives on human hepatocellular carcinoma and mammary adenocarcinoma cell lines
2024
The suppression of increased endothelial permeability by Luteolin: Involvement of protein kinase C and intracellular calcium concentration in vitro.
2023
LC-ESI-MS/MS Analysis of Cleome gynandra Linn. and Melicope ptelefolia Champ. Ex Benth. and Their Anti-Inflammatory Activities in LPS-stimulated RAW 264.7 Cells
2023
Interferon-gamma (IFN-?): Reviewing its mechanisms and signaling pathways on the regulation of endothelial barrier function
2023
Effect of Carcinomas on Autosomal Trait Screening: A Review Article
2022
A Comparison between Metformin Immediate-release and Extended-release: A Review
2021
Synthesis of Novel Esters of Mefenamic Acid with Pronounced Anti-nociceptive Effects and a Proposed Activity on GABA, Opioid and Glutamate Receptors
2021
Effects of 8 Weeks of Balance Training, Virtual Reality Training, and Combined Exercise on Lower Limb Muscle Strength, Balance, and Functional Mobility Among Older Men: A Randomized Controlled Trial
2021
Anti-pyretic activity of two varieties of Hibiscus rosa-sinensis L.
2021
In vitro cytotoxic potential of 3 propionic acid derivatives to normal and cancer liver cell lines
2020
Renal ultrastructural alterations induced byvarious preparations of mefenamic acid
2020
Effects of 4 Thiopurine Compounds on Nitric Oxide Production and Cell Viability of HIG-82 Synoviocytes and RAW 264.7 Macrophages
2019
In vitro characterization and in vivo performance of mefenamic acid-sodium diethyldithiocarbamate based liposomes
2017
A Comprehensive Review on Cosmos caudatus (Ulam Raja) : Pharmacology, Ethnopharmacology, and Phytochemistry
2017
Liposome Encapsulation: A Promising Approach to Enhanced and Safe Mefenamic acid Therapy
2017
Nitric Oxide Production b y Substance P Induced - Murine Raw 264.7 Macrophages
2017
Experimental Review on t he Substance P - Enhanced Endothelial P ermeability i n Human Umbilical Vein Endothelial Cells (HUVECS)
2017
The effect of exergaming on knee proprioception in older men: A randomized controlled trial
2017
Comparative ultrastructural hepatic alterations induced by free and liposome-encapsulated mefenamic acid
2017
Cosmos caudatus extract/fractions reduce smooth muscle cells migration and invasion in vitro: A potential bene?t of suppressing atherosclerosis
2016
Barrier protective effects of Asiatic acid in TNF-alpha induced activation of human aortic endothelial cells
2016
The effect of Everganing on Knee Propioception in older men: A randomized Controlled Trail
2015
Comparative investigation into the anti-ulcer activity of virgin coconut oil and coconut oil in pylorous ligated animal model
2014
IN VITRO ANTI-VIRAL ACTIVITY OF CENTELLA ASIATICA L., CURCUMA LONGAL. AND STROBILANTHES CRISPUS L. AGAINST HERPES VIRUS.
2014
Rapid spectrophotometric determination, characterization and anti-inflammatory efficacy evaluation of nanoencapsulated diclofenac sodium
2014
EVALUATION OF ANTINOCICEPTIVE ACTIVITY OF NANOLIPOSOME-ENCAPSULATED AND FREE FORM DICLOFENAC IN RATS AND MICE
2014
Improved Blood Glucose Level Associated With Polypeptide-K (Diabegard), A Polypeptide Isolated from the Seeds of Momordica charantia Supplementation: Evaluation of 6 Cases
2014
EFFECTS OF CENTELLAASIATICA L., CURCUMA LONGA L., AND STROBILANTHESCRISPUS L. EXTRACTS ON 3 KIDNEY CELL LINES: IN VITRO CYTOTOXICITY ANALYSIS
2014
A Report of Six Clinical Cases of Lowered Blood Cholesterol Profile Associated with Supplementation with Polypeptide K (Diabegard), a Polypeptide Isolated from the Seeds of Momordica charantia Linn
2013
Diuretic Activity of Roots from Carica papaya l. and Ananas comosus L.
2013
Diuretic Activity of Roots from Carica papaya L. and Ananas comous L.
2013
Cytoprotective and enhanced anti-inflammatory activities of liposomal piroxicam formulation in lipopolysaccharide-stimulated RAW 264.7 macrophages
2013
ENHANCED ANTI-INFLAMMATORY EFFECTS OF NANOENCAPSULATED DICLOFENAC
2013
ANTI- INFLAMMATORY EFFECTS OF HIBISCUS ROSA-SINENSIS L. AND Hibiscus ROSA-SINENSIS VAR. ALBA ETHANOL EXTRACTS
2013
Cytoprotective and enhanced anti-inflammatory activities by liposomal piroxicam formulation in lipopolysaccharide-stimulated RAW 264.7 macrophages
2012
The Relationship between Group Cohesion and Team Performance among Volleyball Players: A Malaysian Experience
2012
Liquid chromatography?mass spectrometryelectrospray ionisation analysis of Centella asiatica l., Curcuma longa L. and Strobilanthes crispus L. methanol extracts
2012
The effect of Creatine Monohydrate Supplement on the body composition, among young adults
2012
Effect of Dance Exercise Therapy on Selected Health Parameters among Sedentary Overweight Working Women
2012
In Vitro Anti-diabetic Activities and Chemical Analysis of Polypeptide-k and Oil Isolated from Seeds of Momordica charantia (Bitter Gourd)
2011
Subacute effects of edible film from modified sago starch in rats
2011
Zerumbone isolated from Zingiber zerumbet inhibits inflammation and pain in rats
2011
In vitro anti-fungal and anti-bacterial activity of Drymoglossum piloselloides L. Presl. against several fungi responsible for Athlete?s foot and common pathogenic bacteria
2011
Effects of polypeptide-k supplemented soft bun on blood glucose level in healthy adults
2011
Physical Evaluation of Selected Malaysian National Rugby Players
2011
In vitro anti-fungal and anti-bacterial activity of Drymoglossum piloselloides L. Presl. against several fungi responsible for Athlete?s foot and common pathogenic bacteria.
2011
Preliminary Toxicological Evaluations of Polypeptide-K Isolated from Momordica Charantia in Laboratory Rats
2011
Anti-fungal activity of Ardisia crispa against several fungi responsible for athlete?s foot
2010
Development and characterisation study of liposomes-encapsulated piroxicam
2010
In vitro antimicrobial activity of leaves of Acalypha indica Linn. (Euphorbiaceae)
2009
Selective In vitro Cytotoxic Effects of Piroxicam and Mefenamic Acid on Several Cancer Cell Lines
2009
Diuretic properties of Orthosiphon stamineus Benth
2009
Persistent Organic Chemicals in Malaysian Waters: A review