A
PROFILE
UPM's Staff Profile
YBHG. PROFESOR DR. LING KING HWA
KETUA JABATAN
FACULTY OF MEDICINE AND HEALTH SCIENCES
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PROFESSIONAL

My professional information. Kindly please visit https://www.neurosains.org/ for detailed information.
NAME :
(Ybhg. Profesor Dr.) Ling King Hwa
POSITION :
Ketua Jabatan
ENTITY :
Faculty Of Medicine And Health Sciences

EDUCATIONAL BACKGROUND
2011
DOCTOR OF PHILOSOPHY (Developmental Neurogenetics), Dean's Commendation, 2011
University of Adelaide, Australia.
2005
MASTER OF SCIENCE, (Genetics) With Distinction, 2005
Universiti Putra Malaysia,
UPM Serdang, Selangor DE, Malaysia.
2003
CERTIFICATE, With Distinction, 2003
S* Life Science Informatics Alliance,
S* Online Bioinformatics Course (http://www.s-star.org/)
2002
BACHELOR OF SCIENCE (Biomedical Sciences) Hons., 2002
Universiti Putra Malaysia,
UPM Serdang, Selangor, MALAYSIA.
1998
MALAYSIA HIGHER SCHOOL CERTIFICATE (MHSC), 1998
(Equivalent to A-Level)
Abdul Rahman Talib National Secondary School,
Kuantan, Pahang.
1996
SIJIL PELAJARAN MALAYSIA (SPM), 1996
(Equivalent to O-Level)
Alor Akar National Secondary School,
Kuantan, Pahang.
WORKING EXPERIENCE
2005
June – Dec 2005
TEACHING ASSISTANT
S* Life Science Informatics Alliance,
S* Online Bioinformatics Course
Hosted by the National University of Singapore, Singapore
(www.s-star.org)
2004
2004 – present
TUTOR IN GENETICS & MEDICAL BIOINFORMATICS
Department of Obstetrics & Gynaecology,
Faculty of Medicine and Health Sciences,
Universiti Putra Malaysia,
UPM Serdang, Selangor DE.
2002
2002 – 2004
RESEARCH ASSISTANT
Department of Human Growth and Development,
Faculty of Medicine and Health Sciences,
Universiti Putra Malaysia,
UPM Serdang, Selangor DE.
1998
1998 – 1999
TEMPORARY TEACHER
St Thomas National Secondary School,
Kuantan, Pahang DM.
COURSE ATTENDED
2005
30th June – 4th July 2005 (Level: National)
Malaysian Nationhood Course for Overseas Master/PhD Candidates (KAO-H0994-05) organized by the Biro Tatanegara, Prime Minister Department, Malaysian Government. [Participant]
CONFERENCE / WORKSHOP / SEMINAR
2010
20-22nd Jan 2010
Attachment at Dr Carlos Portera-Cailliau’s laboratory at UCLA, USA. The attachment involved hands-on training on In Utero Electroporation (IUE) technique and was to learn how to surgically construct a cranial window on mouse.
2006
4-8th Sept 2006
8th Melbourne Bioinformatics Course organized by The Walter and Eliza Hall Institute, Melbourne, Victoria, Australia. [Participant]
2005
30th June – 4th July 2005
Malaysian Nationhood Course for Overseas Master/PhD Candidates (KAO-H0994-05) organized by the Biro Tatanegara, Prime Minister Department, Malaysian Government. [Participant]
2005
22nd Feb – 5th Mac 2005
Attachment at the Wellcome Trust Sanger Genome Institute (WTSGI), Hinxton and Institute for Animal Health (IAH), Compton, UK. [Practical training in genome annotation]
2003
8-19th Dec 2003
Workshop on "Genome Sequencing" at MTDC-UKM, Bangi, Selangor, Malaysia. [Facilitator]
2003
6-7th Oct 2003
Workshop on "gRNA – Genomics Research Network and Architecture" at MTDC-UKM, Bangi, Selangor, Malaysia. [Participant]
2003
28th July 2003
Training on "Statistical Methods for Experimental Research" organized by Faculty of Veterinary Medicine, UPM, Selangor, Malaysia, and UPM Veterinary Alumni. [Participant]
2003
8-11th Jan 2003
Workshop on "Automated Sequencing: ABI PRISM 3730 Genetic Analyzer" at MTDC-UKM, Bangi, Selangor, Malaysia. [Participant]
2002
16-20th Dec 2002
Workshop on "Genome Informatics" at MTDC-UKM, Bangi, Selangor, Malaysia. [Participant]
2002
5-9th Aug 2002
Workshop on "Bioinformatics Tools for Molecular Biologist" at MTDC-UKM, Bangi, Selangor, Malaysia. [Participant]
2002
30-31st May 2002
Workshop on "Automated Sequencing: ABI PRISM 377" at Faculty of Biotechnology, Universiti Putra Malaysia, Serdang, Selangor, Malaysia. [Participant]
2002
15-19th April 2002
Workshop on "Detection of Sequence Variants: Real-Time PCR and WAVE™ Technology" at CGAT, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia. [Participant]
2001
Mac-May 2001
Clinical laboratory training, Department of Pathology, Kuantan General Hospital,
Pahang, Malaysia.
PAPER PRESENTED
2010
14-19th Jan 2010
M1181: A novel miRNA involved in development of the mouse embryo. Keystone Symposia Conference, Colorado, USA. [Poster presenter]
2009
15-17th Nov 2009
Functional analysis of novel antisense transcripts at Sox4 gene locus during mouse cerebral corticogenesis. The Australian Society for Medical Research (ASMR) National Sci. Conference, Hobart, Tasmania, Australia. [Poster presenter]
2009
1st Sept 2009
Discovery of a novel microRNA that may involve in early development of the mouse brain, neuronal differentiation and embryonic stem cell. FHS 2009 Postgraduate Research Expo, Adelaide, South Australia, Australia. [Poster presenter]
2009
2nd June 2009
Discovery of novel miRNAs in the developing mouse brain by in depth sequencing of small RNAs. The Australian Society for Medical Research, SA 2009 Scientific Meeting, Adelaide, South Australia, Australia. [Poster presenter]
2008
22nd Jul 2008
Global expression analysis revealed spatio-temporal regulation and genomic clustering of Sox4 sense-antisense transcripts during cerebral corticogenesis in the mouse. FHS 2008 Postgraduate Research Expo, SA, Australia. [Poster presenter]
2008
17-21st Feb 2008
Global expression analysis of the developing mouse cerebral cortex reveals spatio-temporal regulation of sense and antisense expressions. 29th Lorne Genome Conference, Victoria, Australia. [Poster presenter]
2007
5th Jul 2007
High-throughput validation of mouse brain expression data using Roche Universal Probe Library (UPL) and LC480 real time PCR instrument. Genomic Disorder Research Centre Seminar Series, Melbourne University. [Invited Speaker]
2007
12-17th Jul 2007
Global expression analysis and identification of novel regulatory networks during cortical development in mouse. The IBRO World Congress of Neuroscience, Victoria, Australia. [Poster presenter]
2007
5-7th May 2007
A single nucleotide polymorphism of the human fatty acid amide hydrolase gene (FAAH): Risk of drug addiction in Malaysian subjects. The 7th National Congress on Genetics, Kelantan, Malaysia. [Co-author for poster]
2006
26th Nov-1st Dec 2006
Neuropathology and global gene expression in Ts1Cje, a mouse model of Down syndrome. The 3rd Australian Health and Medical Research Congress (AH&MRC),Victoria, Australia. [Co-author for poster]
2005
29th April 2005
Sequencing, assembly and analysis of chromosome one of Eimeria tenella. Sequencing Workshop, National Genome Institute, Malaysia. [Invited Speaker]
2005
4-5th April 2005
Sequencing and analysis of chromosome one of Eimeria tenella. 15th Malaysian Society for Molecular Biology and Biotechnology (MSMBB), Berjaya Times Square Hotel, Kuala Lumpur. [Invited Speaker]
2005
24-25th Feb 2005
Assembly, finishing and sequence analysis of chromosome one of Eimeria tenella. 3rd Eimeria Genome Consortium Meeting, Wellcome Trust Sanger Genome Institute, Hinxton, United Kingdom. [Oral presenter]
2004
20th-21st Dec 2004
High-throughput sequencing and analysis of chromosome one of Eimeria tenella. The 4th Annual Seminar for National Science Fellowship 2004, jointly organized by the MOSTI and USM, Pulau Pinang, Malaysia. [Oral presenter]
2004
8-10th Jan 2004
Sequencing analysis of chromosome one of Eimeria tenella. 2nd Annual Microbial Genomics Top-Down Projects Meeting, Pan Pacific Hotel, Pangkor Island. [Oral presenter]
2003
12-25th May 2003
High-throughput sequencing of chromosome one of Eimeria tenella. Eimeria Genome Consortium Meeting at Institute of Animal Health, Compton, United Kingdom. [Oral presenter]
2003
3-5th Dec 2003
GAP4: Multiple Integrated Assemblies – Toward the generation of a complete sequence of chromosome one of Eimeria tenella. 8th Biological Sciences Graduate Congress, National University of Singapore, Singapore. [Poster presenter]
2003
8-10th Sept 2003
A survey of repetitive elements in chromosome one and two of Eimeria tenella. International Conference on Bioinformatics, Penang, Malaysia. [Co-author for poster]
2003
8-10th Sept 2003
The assembly and generation of a draft sequence for chromosome one of Eimeria tenella. International Conference on Bioinformatics, Penang, Malaysia. [Poster Presenter]
2003
12th Aug 2003
A survey of DNA repeats in chromosome one and two of Eimeria tenella. 28th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, Putrajaya, Malaysia. [Co-author for poster]
2003
12hb Aug 2003
Detection of the angiotensinogen gene M235T variant and its association with essential hypertension and plasma renin activity in Malaysian subjects. 28th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology,
2003
2-6th Jul 2003
The angiotensinogen M235T gene Variants and its association with essential hypertension and plasma renin activity in Malaysian subjects. 7th International Symposium on Mutations in the Genome. Palm Cov. Australia. [Co-author for poster]
2003
8-10th June 2003
High-throughput sequencing of chromosome one of Eimeria tenella for gene discoveries. Universiti Putra Malaysia 2003 R&D Exhibition, PKSSAAS Hall, Universiti Putra Malaysia, Selangor, Malaysia. [Poster presenter]
2002
22nd-24th May 2002
The prevalence of MTHFR677C-T missense mutation, total homocysteine levels and associated risk factors in Malay subjects. Young Researcher awards for MSMBB, Selangor. [Oral presenter]
TEACHING
2010
Human Genetics Module (SPP3251) - MD programme.
2010
Medical Genetics (HGD5502) - Postgrad. MSc/PhD
2010
Gene Expression Module (SPP3241) - MD programme.
AWARD AND ACHIEVEMENT
2009
Best Poster Presentation Award – SA, Australia level, 2009
The Australian Society for Medical Research.
2009
Discipline of Medicine Travelling Fund, UoA, 2009 – AUD500.00
To Keystone Symposia Conference in Colorado, USA.
2009
FHS Postgraduate Travelling Fellowship Award, UoA, 2009 – AUD1500.00
To Keystone Symposia Conference in Colorado, USA.
2008
AFSI equivalent – International Level, 2008 - 2010
Adelaide Fees Scholarship International for pursuing PhD degree in The University of Adelaide, Adelaide, Australia.
2007
Marquis Who’s Who in the World 2007 – International Level, 2007
Listed biographee in Marquis Who’s Who in the World 2007 edition.
2006
UPM Scholarship – University Level, 2006 - 2009
Universiti Putra Malaysia Staff Training Scholarship for pursuing PhD degree in The University of Melbourne, Victoria, Australia.
2006
MIFRS Scholarship – International Level, 2006 - 2008
Melbourne International Fee Remission Scholarship for pursuing PhD degree in The University of Melbourne, Victoria, Australia.
2006
Excellence Service Award – University Level, 2006
For excellence service provided in the year 2006 at the Faculty of Medicine and Health Sciences, Universiti Putra Malaysia.
2004
Gold Prize – National Level, 2004
For the best oral presentation (Biotechnology Section)
4th Annual Seminar for National Science Fellowship 2004
Ling KH, Rosli R, Shamsudin MN, Mohamed R, Wan KL. High-throughput sequencing and analysis of chrom
2003
Silver Medal Award – University Level, 2003
UPM 2003 Research & Development Exhibition.
2003
Best Poster Presentation Award – National Level, 2003
The Malaysian Society for Biochemistry and Molecular Biology (MSBMB).
2003
Certificate of Appreciation – National Level, 2003
For the contribution to the rapid genome sequencing, assembly and analysis of two coronavirus genomes.
By The Ministry of Science, Technology and Environment.
2002
National Science Fellowship (NSF) – National Level, 2002 – 2004
Ministry of Science, Technology and Environment, Malaysia.
1996
Excellent Award for Sijil Pelajaran Malaysia – School Level, 1996
For Excellent Achievement in Science
Alor Akar National Type Secondary School, Kuantan, Pahang DM, Malaysia.
1996
Model Student Award – School Level, 1996
Alor Akar National Type Secondary School,
Kuantan, Pahang DM, Malaysia.
1996
Excellent Award for Sijil Pelajaran Malaysia – State Level, 1996
For Excellent SPM Achievement
Pahang State Foundation, Malaysia.
AREA OF SPECIALISATION
Genomics and transcriptomics
Developmental Neurogenetics
RESEARCH AREA
Role of Sox4 sense and antisense transcripts in brain and cancer development.
Discovery of new genes/transcripts/small RNAs during mammalian or disease development.
The biology and genetics of long non-coding RNA during mammalian development.
PUBLICATION
2022:
Interplay between Maternal and Neonatal Vitamin D Deficiency and Vitamin-D-Related Gene Polymorphism with Neonatal Birth Anthropometry
2022:
Mesenchymal Stromal Cells‑Derived Exosome and the Roles in the Treatment of Traumatic Brain Injury
2021:
Human iPS-derived pre-epicardial cells direct cardiomyocyte aggregation expansion and organization in vitro
2021:
Asymptomatic neurotoxicity of amyloid β-peptides (Aβ1-42 and Aβ25-35) on mouse embryonic stem cell-derived neural cells
2021:
Barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel in situ analyses
2021:
Serotonergic receptor gene polymorphism and response to selective serotonin reuptake inhibitors in ethnic Malay patients with first episode of major depressive disorder
2021:
Transient prenatal ruxolitinib treatment suppresses astrogenesis during development and improves learning and memory in adult mice
2021:
Chemoresistance in breast cancer: PI3K/Akt pathway inhibitors vs the current chemotherapy
2021:
Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin
2021:
Assessing the Entrepreneurial Management amongst Bahrain SMEs
2021:
Influence of Perceived Value and Innovation on the Propensity To Use Sports Tourism Websites among University Students: The Moderating Effects of Age and Education
2021:
Inadequate vitamin D intake among pregnant women in Malaysia based on revised recommended nutrient intakes value and potential dietary strategies to tackle the inadequacy
2021:
The expression profile of miR-3099 during neural development of Ts1Cje mouse model of Down syndrome
2020:
Limited expression of non-integrating CpG-free plasmid is associated with increased nucleosome enrichment
2020:
BsmI-ApaI-TaqI TAC (BAt) Haplotype of Vitamin D Receptor Gene Is Associated with Increased Risk of Major Depressive Disorder.
2020:
Influence of vitamin D binding protein polymorphism, demographics and lifestyle factors on vitamin D status of healthy Malaysian pregnant women
2020:
Single nucleotide polymorphism of BDNF Val66Met (rs6265) and its association to neuropsychiatric disorders
2020:
Predictors of Recurrence of Major Depressive Disorder
2020:
Influence of lead and zinc oxides on the radiation shielding properties of tellurite glass systems
2020:
Antiviral treatment options for COVID-19 by reduction of viral load and viral shedding
2020:
Phenotype microarrays reveal metabolic dysregulations of neurospheres derived from embryonic Ts1Cje mouse model of Down syndrome
2020:
Plasma proteome profiling reveals differentially expressed lipopolysaccharide-binding protein among leptospirosis patients
2020:
Human Mesenchymal Stem Cells-mediated Transcriptomic Regulation of Leukemic Cells in Delivering Anti-tumorigenic Effects
2020:
Lapatinib as a Dual Tyrosine Kinase Inhibitor Unexpectedly Activates Akt in MDA-MB-231 Triple-Negative Breast Cancer Cells
2020:
Hypocalcemia, hypochloremia, and eosinopenia as clinical predictors of leptospirosis: A retrospective study
2020:
Penterjemahan Idiom Arab-Melayu Melalui Google Translate: Apakah yang Perlu Dilakukan?
2020:
Association of Maternal and Cord Plasma Total, Free and Bioavailable 25-Hyrodroxyvitamin D with Neonatal Anthropometric Measurements at Birth: A Preliminary Study in a Private Hospital
2020:
Development and Differentiation of Midbrain Dopaminergic Neuron: From Bench to Bedside