PROFILE

UPM's Staff Profile

PROF. MADYA DR. HO KOK LIAN

ASSOCIATE PROFESSOR

FACULTY OF MEDICINE AND HEALTH SCIENCES

klho@upm.edu.my

PROFESSIONAL

UPM WEBSITE

PROFILE

klho

PROFESSIONAL

NAME :

(Prof. Madya Dr.) HO KOK LIAN

POST :

ASSOCIATE PROFESSOR

ENTITY :

FACULTY OF MEDICINE AND HEALTH SCIENCES

FIELD OF SUPERVISION

MEDICAL BIOTECHNOLOGY / MOLECULAR BIOLOGY AND GENETIC ENGINEERING / MOLECULAR BIOTECHNOLOGY / PATHOLOGY / STRUCTURAL BIOLOGY

EDUCATION

PHD
UNIVERSITY OF EDINBURGH, SCOTLAND, UNITED KINGDOM
Graduated : 2009

MASTER (SAINS)
UNIVERSITI PUTRA MALAYSIA, SERDANG, SELANGOR
Graduated : 2002

BACELOR SAINS
UNIVERSITI PUTRA MALAYSIA, SERDANG, SELANGOR
Graduated : 1999

JOURNAL PUBLICATION

1. A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

2. Cryo-Electron Microscopy Structure of the Macrobrachium rosenbergii Nodavirus Capsid at 7 Angstroms Resolution
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

3. Native agarose gel electrophoresis and electroelution: A fast and cost-effective method to separate the small and large hepatitis B capsids
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

4. An Influenza A Vaccine Based on the Extracellular Domain of Matrix 2 Protein Protects BALB/C Mice Against H1N1 and H3N2
Journal type: Citation-Indexed - Scopus

5. Crystallization and preliminary crystallographic studies of the hypothetical protein BPSL 1038 from Burkholderia pseudomallei
Journal type: Non Citation-Indexed

6. Virus like particles as a platform for cancer vaccine development
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

7. Crystallization and X-ray crystallographic analysis of recombinant TylP, a putative γ-butyrolactone receptor protein from Streptomyces fradiae
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

8. Cloning, expression, purification, crystallization and X-ray crystallographic analysis of recombinant human C1ORF123 protein
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

9. Cloning, expression, purification, characterization, crystallization and X-ray crystallographic analysis of recombinant Der f 21 (rDer f 21) from Dermatophagoides farinae
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

10. Expression, purification and characterization of the dimeric protruding domain of Macrobrachium rosenbergii nodavirus capsid protein expressed in Escherichia coli
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

11. Structure of the Macrobrachium rosenbergii nodavirus: A new genus within the Nodaviridae?
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

12. Crystal structure and functional analysis of human C1ORF123
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

13. Structural and kinetic studies of a novel nerol dehydrogenase from Persicaria minor, a nerol-specific enzyme for citral biosynthesis
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

14. Single-step purification of recombinant hepatitis B core antigen Y132A dimer from clarified Escherichia coli feedstock using a packed bed anion exchange chromatography
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

15. Crystal structure and epitope analysis of house dust mite allergen Der f 21
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

16. Synthesis of poly (acrylamide)-based hydrogel for bio-sensing of hepatitis B core antigen
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

17. Comparative Overview of Hepatitis B Virus and Domestic Cat Hepadnavirus From the Perspective of Viral Biology to Capsid Protein and Its Applications
Journal type: Citation-Indexed - Scopus

18. Immunological Analysis of Nodavirus Capsid Displaying the Domain III of Japanese Encephalitis Virus Envelope Protein
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

19. Production of Novel Antimicrobial Peptide Human Beta-defensin 9 (hBD9) Using the Pet Sumo Expression System in Escherichia coli and Characterisation of Its Antimicrobial Activity
Journal type: Citation-Indexed - Scopus

20. Virus-like Particles of Nodavirus Displaying the Receptor Binding Domain of SARS-CoV-2 Spike Protein: A Potential VLP-Based COVID-19 Vaccine
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

21. Structural and functional analyses of Burkholderia pseudomallei BPSL1038 reveal a Cas-2/VapD nuclease sub-family
Journal type: Citation-Indexed Journal - Science Citation Index (JCR)

22. Production and Characterisation of Dimeric Spike Truncated-Nodavirus Capsid Displaying the Receptor-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus-2
Journal type: Citation-Indexed - Scopus

PUBLICATION

2024

Production and Characterisation of Dimeric Spike Truncated-Nodavirus Capsid Displaying the Receptor-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus-2

2023

Structural and functional analyses of Burkholderia pseudomallei BPSL1038 reveal a Cas-2/VapD nuclease sub-family

2023

Virus-like Particles of Nodavirus Displaying the Receptor Binding Domain of SARS-CoV-2 Spike Protein: A Potential VLP-Based COVID-19 Vaccine

2021

Immunological Analysis of Nodavirus Capsid Displaying the Domain III of Japanese Encephalitis Virus Envelope Protein

2021

Production of Novel Antimicrobial Peptide Human Beta-defensin 9 (hBD9) Using the Pet Sumo Expression System in Escherichia coli and Characterisation of Its Antimicrobial Activity

2020

Synthesis of poly (acrylamide)-based hydrogel for bio-sensing of hepatitis B core antigen

2019

An Influenza A Vaccine Based on the Extracellular Domain of Matrix 2 Protein Protects BALB/C Mice Against H1N1 and H3N2

2019

Expression, purification and characterization of the dimeric protruding domain of Macrobrachium rosenbergii nodavirus capsid protein expressed in Escherichia coli

2019

Crystal structure and epitope analysis of house dust mite allergen Der f 21

2018

Structure of the Macrobrachium rosenbergii nodavirus: A new genus within the Nodaviridae?

2018

Crystal structure and functional analysis of human C1ORF123

2018

Structural and kinetic studies of a novel nerol dehydrogenase from Persicaria minor, a nerol-specific enzyme for citral biosynthesis

2018

Single-step purification of recombinant hepatitis B core antigen Y132A dimer from clarified Escherichia coli feedstock using a packed bed anion exchange chromatography

2017

Crystallization and X-ray crystallographic analysis of recombinant TylP, a putative ?-butyrolactone receptor protein from Streptomyces fradiae

2017

Virus like particles as a platform for cancer vaccine development

2017

Cryo-Electron Microscopy Structure of the Macrobrachium rosenbergii Nodavirus Capsid at 7 Angstroms Resolution

2016

A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence

2016

Cloning, expression, purification, crystallization and X-ray crystallographic analysis of recombinant human C1ORF123 protein

2015

Cloning, expression, purification, characterization, crystallization and X-ray crystallographic analysis of recombinant Der f 21 (rDer f 21) from Dermatophagoides farinae

2013

Native agarose gel electrophoresis and electroelution: A fast and cost-effective method to separate the small and large hepatitis B capsids

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