PROFILE
Laman Web Staf UPM
DR. FONG LAI YEN
PROFESOR MADYA
FAKULTI PERUBATAN DAN SAINS KESIHATAN
fonglaiyen@upm.edu.my
PROFESIONAL
NAMA :
(Dr.) FONG LAI YEN
JAWATAN :
PROFESOR MADYA
PTJ :
FAKULTI PERUBATAN DAN SAINS KESIHATAN
LATARBELAKANG PENDIDIKAN
PENGALAMAN KERJA
PERKHIDMATAN PERUNDINGAN
PENGAJARAN
BIDANG PENYELIDIKAN
PROJEK PENYELIDIKAN
2025
Evaluation of the effect of 3,6-Bis[4-(dimethylamino)butoxy]-1-hydroxyxanthone (AMSD-2) on tumor necrosis factor alpha (TNF-α)-induced endothelial activation (Member), Universiti Tunku Abdul Rahman (UTAR) Research Fund, 2025-2026, RM 54,100
2024
Investigation Of effect Of 3,6-Bis[4-(Dimethylamino)Butoxy]-1-Hydroxy-9H-Xanthen-9-Xanthone (AMSD-1), A New Xanthone Derivative, On Tumor Necrosis Factor Alpha (TNF-α)-Induced Endothelial Barrier Dysfunction (PI), Universiti Tunku Abdul Rahman (UTAR) Research Fund, 2024 - 2025, RM 27,750
2022
Evaluation of effect of a new xanthone derivative, 3-phenylbutylxanthone, on TNF-α-induced endothelial activation (PI), Universiti Tunku Abdul Rahman (UTAR) Research Fund, 2022-2023, RM 47,100
2021
Effects of epigallocatechin-3-gallate in restoration of insulin resistance, hyperglycaemia and dyslipidaemia in a rodent model (Member), Universiti Tunku Abdul Rahman (UTAR) Research Fund, 2021-2022, RM 59,100
2021
Investigation of roles of RhoA and ROCK as potential therapeutic targets in Interferon-γ-induced disruption of human umbilical vein endothelial cells (HUVECs) barrier function (Member), Fundamental Research Grant Scheme, 2021 - 2023, RM 144,850
2021
Elucidation of the effect of lauric acid in hepatic steatosis and insulin resistance in diet-induced obese mice (Member), Fundamental Research Grant Scheme, 2021 - 2023, RM 145,500
2021
Investigation of effect of asiatic acid on plasma lipid profile and proinflammatory markers in high-fat-diet-fed apoE-deficient mice (PI), Universiti Tunku Abdul Rahman (UTAR) Research Fund, 2021-2022, RM 27,000
2020
Unraveling the potential of Malaysian Tualang Honey in combating pathogenesis of atherosclerosis initiated by vascular smooth muscle cells: the mechanisms in vitro and in vivo (Member), Fundamental Research Grant Scheme, 2020-2023, RM159,000
2020
Evaluation of effects of Alternanthera sessilis ethanol extract on TNF-α-induced oxidative stress and endothelial dysfunction on human aortic endothelial cells (PI), Universiti Tunku Abdul Rahman (UTAR) Research Fund, 2020-2021, RM 57,400
2019
Investigation of the effects of asiatic acid on pre-lesional atherogenic events in vitro and atherosclerotic lesion formation in vivo (PI), Fundamental Research Grant Scheme, 2019 - 2022, RM 177,200
2019
Evaluation of Maslinic acid Treatment Efficacy in NOD Scid Gamma (NSG) mice with Colorectal Cancer Xenografts and Transcriptomics Profiling (Member), Fundamental Research Grant Scheme, 2019 - 2022, RM111,600
2018
Interaction of Camellia sinensis with P-glycoprotein transport system and its impact on nadololpharmacokinetics in hypertensive animal model (Member), Universiti Tunku Abdul Rahman Research Fund, 2018-2019, RM 50,500
2017
Asiatic acid improves endothelial barrier function via inhibition of VCAM-1 and oxidative stress (PI), Universiti Tunku Abdul Rahman Research Fund, 2017 - 2018, RM 63,000
2012
In vitro evaluation on the Anti-atherogenic effects of asiaticoside in Endothelial cells (PI), MTSF Science & Technology Research Grant, 2012-2014, RM 15,000