A
PROFILE
UPM's Staff Profile
YBHG. PROFESOR DR. CHEAH PIKE SEE
HEAD OF DEPARTMENT
FACULTY OF MEDICINE AND HEALTH SCIENCES
cheahpikesee@upm.edu.my
cheahpikesee
BM
EN

PROFESSIONAL

NAME :
(Ybhg. Profesor Dr.) CHEAH PIKE SEE
MANAGERIAL POSITION :
HEAD OF DEPARTMENT
ENTITY :

PERMANENT POST :
PROFESSOR
ENTITY :
FACULTY OF MEDICINE AND HEALTH SCIENCES

FIELD OF SUPERVISION
HUMAN ANATOMY / NEUROSCIENCE / MOLECULAR BIOLOGY AND GENETIC ENGINEERING / MOLECULAR MEDICINE


PUBLICATION
2025
Lithium restores nuclear REST and Mitigates oxidative stress in down syndrome iPSC-Derived neurons
2025
Engineered AAV capsids mediate transduction of murine neurofibroma and sciatic nerve
2025
Renoprotective and antihypertensive mechanism of action of Clinacanthus nutans bioactive polysaccharides by suppression of reactive oxygen species/ nuclear factor/ matrix metalloproteinase (ROS/NF-?B/MMP-9) and upregulation of endothelial nitric oxid
2024
In vitro Cytotoxicity Assessment of Ruxolitinib on Oligodendrocyte Precursor Cell and Neural Stem/Progenitor Cell Populations
2024
A cadaveric study of anatomical variation of sphenoparietal sinus and superficial sylvian draining veins
2024
Prenatal Ruxolitinib Treatment Improved Muscle Strength But Showed no Impact on the Neurobehavioral and Electrophysiological Traits in Adult Mice
2023
Mitochondrial Dysfunction in Down Syndrome: From Pathology to Therapy
2023
REST in the Road Map of Brain Development
2023
Evaluation of toxicity profile of kratom (Mitragyna speciosa Korth) decoction in rats
2022
Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2
2022
Recent Advances in the Therapeutic Strategies of Glioblastoma Multiforme
2022
CRISPR-Cas knockout of miR21 reduces glioma growth
2021
TAF1 Transcripts and Neurofilament Light Chain as Biomarkers for X?linked Dystonia?Parkinsonism
2021
Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin
2021
AAV9 transduction mediated by systemic delivery of vector via retro-orbital injection in newborn, neonatal and juvenile mice
2020
Glioma-Derived miRNA-Containing Extracellular Vesicles Induce Angiogenesis by Reprogramming Brain Endothelial Cells
2020
Plasmon-enhanced biosensing for multiplexed profiling of extracellular vesicles
2020
Discovery and Verification of Extracellular miRNA Biomarkers for Non-invasive Prediction of Preeclampsia in Asymptomatic Women
2020
Mutant Allele-Specific CRISPR Disruption in DYT1 Dystonia Fibroblasts Restores Cell Function
2020
Phenotype microarrays reveal metabolic dysregulations of neurospheres derived from embryonic Ts1Cje mouse model of Down syndrome
2020
The nootropic and anticholinesterase activities of Clitoria ternatea Linn. root extract: Potential treatment for cognitive decline
2020
Mitragynine Attenuates Morphine Withdrawal Effects in Rats—A Comparison With Methadone and Buprenorphine
2019
Perturbed metabolic profiles associated with muscle weakness seen in adult Ts1Cje mouse model of Down syndrome
2019
Long-Term Therapeutic Efficacy of Intravenous AAV-Mediated Hamartin Replacement in Mouse Model of Tuberous Sclerosis Type 1
2019
Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21
2019
Stearoyl CoA Desaturase Is Essential for Regulation of Endoplasmic Reticulum Homeostasis and Tumor Growth in Glioblastoma Cancer Stem Cells
2019
Promoting Neuro-Supportive Properties of Astrocytes with Epidermal Growth Factor Hydrogels
2019
Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles
2018
Defects in nerve conduction velocity and different muscle fibre-type specificity contribute to muscle weakness in Ts1Cje Down syndrome mouse model
2018
Ultrastructural study of sciatic nerve in Ts1Cje mouse model for Down syndrome: an implication of peripheral nerve defects in hypotonia
2018
Isolation, cultivation and immunostaining of single myofibers: An improved approach to study the behavior of satellite cells
2018
Expression Profiling of Genes Involved in the Development and Function of Skeletal Muscles in Ts1Cje Mouse Model of Down Syndrome
2017
Molecular characterization of glycation-associated skin ageing: an alternative skin model to study in vitro antiglycation activity of topical cosmeceutical and pharmaceutical formulations
2017
Anatomic Variation in Morphometry of Human Coracoid Process among Asian Population
2016
Spatiotemporal expression and molecular characterization of miR-344b and miR-344c in the developing mouse brain
2016
Identification of the genomic mutation in Epha4rb-2J/rb-2J mice
2015
SOX3 expression in the glial system of the developing and adult mouse cerebellum
2014
Harvesting the maximum length of sciatic nerve from adult mice: a step-by-step approach
2013
Expression of the murine transcription factor SOX3 during embryonic and adult neurogenesis.
2012
Congenital Hydrocephalus and Abnormal Subcommissural Organ Development in Sox3 Transgenic Mice
2012
Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3zeta deficiency
2011
Deep sequencing analysis of the developing mouse brain reveals a novel microRNA
2011
Spatiotemporal Regulation of Multiple Overlapping Sense and Novel Natural Antisense Transcripts at the Nrgn and Camk2n1 Gene Loci during Mouse Cerebral Corticogenesis
2010
Molecular genetics of the developing neuroendocrine hypothalamus
2009
Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling
2008
Histomorphometrical profile of the corneal response to short-term reverse-geometry orthokeratology lens wear in primate cornea ? pilot study(in print)
2008
Histomorphic profile of the corneal response to short-term reverse geometry orthokeratology lens wear in primate corneas: a pilot study.
2008
Expression of Notch-1 receptor and its ligands Jagged-1 and Delta-1 in amoeboid microglia in postnatal rat brain and murine BV-2 cells.
2008
The resin-embedded cornea prepared via rapid processing protocol : a good histomorphometric target for clinical investigation in opthalmologyand optometry
2007
Ketamine-xylazine/tiletamine-zolazepam prolonged anesthesia in Cynomolgus monkeys.