A
PROFILE
Laman Web Staf UPM
PROF. MADYA DR. THAM CHAU LING
PROFESOR MADYA
FAKULTI PERUBATAN DAN SAINS KESIHATAN
chauling@upm.edu.my
Laman Web UPM
PROFILE
chauling
BM
EN

PROFESIONAL

NAMA :
(Prof. Madya Dr.) THAM CHAU LING
JAWATAN :
PROFESOR MADYA
PTJ :
FAKULTI PERUBATAN DAN SAINS KESIHATAN

BIDANG PENYELIAAN
IMMUNOBIOLOGY / IMMUNOPHARMACOLOGY / MOLECULAR MEDICINE
PENDIDIKAN
PHD
UNIVERSITI PUTRA MALAYSIA, SERDANG, SELANGOR
Graduated : 2012
BACELOR SAINS (KEPUJIAN)
UNIVERSITI PUTRA MALAYSIA, SERDANG, SELANGOR
Graduated : 2007
PENERBITAN BUKU
1. Problem Based Learning in Biomedical Sciences
    ISPN: 978-967-344-650-6
PENERBITAN JOURNAL
1. Inhibition of epithelial CC-family chemokine synthesis by the synthetic chalcone DMPF-1 via disruption of NF-kB nuclear translocation and suppression of experimental asthma in mice
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
2. Anti-allergic activity of 2,4,6-trihydroxy-3-geranylacetophenone (tHGA) via attenuation of IgE-mediated mast cell activation and inhibition of passive systemic anaphylaxis
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
3. Barrier protective effects of 2,4,6-trihydroxy-3-geranyl acetophenone on lipopolysaccharides-stimulated inflammatory responses in human umbilical vein endothelial cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
4. Development and Validation of a Bioanalytical Method for Quantification of 2,6-Bis-(4-Hydroxy-3-Methoxybenzylidene)-Cyclohexanone (BHMC) in Rat Plasma
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
5. LAT is Essential for the Mast Cell Stabilising Effect of tHGA in IgE-Mediated Mast Cell Activation
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
6. Clinacanthus nutans Aqueous Extract But Not Ethanolic Extract Inhibits the Release of Preformed Mediators in In Vitro Model of IgE-Mediated Mast Cell Degranulation
    Journal type: Non Citation-Indexed
7. IgG-Mediated Anaphylaxis: Biomarker Identification via Meta-Analysis
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
8. Major Bioactive Compounds in Essential Oils Extracted from the Rhizomes of Zingiber zerumbet (L) Smith: A Minireview on the AntiAllergic and Immunomodulatory Properties
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
9. Association of Immunoglobulin G Abnormalities in Diseases: A Mini Review
    Journal type: Non Citation-Indexed
10. Mast Cells in Allergy: The Potential Molecular Targets in the Upstream Signalling Pathways
    Journal type: Non Citation-Indexed
11. Mast cell stabilizing effect of a geranyl acetophenone in dengue virus infection using in vitro model of DENV3-induced RBL-2H3 cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
12. Effect of Diarylpentanoid Analogues on Lipopolysaccharide- Induced Interleukin-6 and Interleukin-8 Gene Expression in Airway Inflammation
    Journal type: Citation-Indexed - Scopus
13. Differential regulation of LPS-mediated VE-cadherin disruption in human endothelial cells and the underlying signaling pathways: A mini review.
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
14. Clinacanthus nutans Aqueous Extract Suppresses the Release of Histamine and β-hexosaminidase in In Vitro Model of IgE-Mediated Mast Cell Degranulation
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
15. A Review of Malaysian Herbal Plants and Their Active Constituents with Potential Therapeutic Applications in Sepsis
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
16. The Potential Use of Honey as a Remedy for Allergic Diseases: A Mini Review
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
17. IgE-mediated sensitizations to Blomia tropicalis allergens in Malaysian allergic population
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
18. 2,4,6-Trihydroxy-3-Geranyl Acetophenone Suppresses Vascular Leakage and Leukocyte Infiltration in Lipopolysaccharide-Induced Endotoxemic Mice
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
19. Pharmacological Properties of 2,4,6-Trihydroxy-3-Geranyl Acetophenone and the Underlying Signaling Pathways: Progress and Prospects
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
20. Zerumbone Attenuates House Dust Mite-Induced Epithelial Barrier Dysfunction in 16HBE14o- Cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
21. Anti-allergic Properties of Propolis: Evidence from Preclinical and Clinical Studies
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
22. MANAGEMENT OF ATOPIC DERMATITIS VIA ORAL AND TOPICAL ADMINISTRATION OF HERBS IN MURINE MODEL: A SYSTEMATIC REVIEW
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
23. Rhinovirus-Induced Cytokine Alterations with Potential Implications in Asthma Exacerbations: A Systematic Review and Meta-Analysis
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
24. Sensitization effect of Kaempferol from Persimmon leaves on Hepatoma Cells with ABT-199 resistance and its molecular mechanisms
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
25. Alcohol Withdrawal and the Associated Mood Disorders—A Review
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
26. Ameliorative Effect of Tocotrienols on Perimenopausal-Associated Osteoporosis—A Review
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
27. Clinacanthus nutans Aqueous Extract Exerts Anti-Allergic Activity in Preclinical Anaphylactic Models via Alternative IgG Pathway
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
28. House dust mite allergy in Malaysia: review of research gaps in the current scenario and the way forward
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
29. The Anti-Allergic Potential of Stingless Bee Honey from Different Botanical Sources via Modulation of Mast Cell Degranulation
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
30. Insight parameter drug design for human β-tryptase inhibition integrated molecular docking, QSAR, molecular dynamics simulation, and pharmacophore modelling studies of α-keto-[1,2,4]-oxadiazoles
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
31. Menopause-associated depression: Impact of Oxidative Stress and Neuroinflammation on the Central Nervous System – A Review
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
32. Neuroprotective effects of Gypenosides: A review on preclinical studies in neuropsychiatric disorders
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
33. Flavonoid diversity and roles in the lipopolysaccharide-mediated inflammatory response of monocytes and macrophages
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
34. Drug discovery and development: A historical overview, current challenges and perspectives
    Journal type: MYCITE
35. Student acceptance towards AsepticTech VR: a teaching and learning tool for cell and tissue culture aseptic techniques
    Journal type: Citation-Indexed Journal - Social Science Citation Index (JCR)
36. Acquisition of aseptic techniques using virtual reality: A randomized trial on performance, emotion and experience
    Journal type: Citation-Indexed Journal - Social Science Citation Index (JCR)
37. Ameliorative effect of α-tocopherol and tocotrienol-rich palm oil extract on menopausal-associated mood disorder in ovariectomised mice
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
38. Oral and Topical Administration of a Geranyl Acetophenone Attenuates DNCB-induced Atopic Dermatitis-like Skin Lesions in BALB/c Mice
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
39. A synthetic curcumin‑like diarylpentanoid analog inhibits rhinovirus infection in H1 hela cells via multiple antiviral mechanisms
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
40. USP14 inhibits sensitization-mediated degradation of KDM4D to epigenetically regulate dendritic cell tolerogenic capacity and mitigates airway allergy
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
41. Inhibition of Junctional Protein Disruption by 2,4,6-Trihydroxy-3-Geranyl Acetophenone in Lipopolysaccharide-Induced Endothelial Hyperpermeability via GEF-H1/RhoA/ROCK Pathway
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
42. Curcumin‑like diarylpentanoid analogues exhibit antiviral and anti‑inflammatory activities in influenza A virus‑infected A549 lung epithelial cells by inhibiting multiple retinoic acid‑inducible gene I (RIG‑I)‑mediated pathways
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
43. Therapeutic Targeting of Neuroinflammation in Methamphetamine Use Disorder
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
44. Regulation of elevated expression of Mcl-1 in hepatocellular carcinoma – a review
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
45. Chronic Stress-Associated Depressive Disorders: The Impact of HPA Axis Dysregulation and Neuroinflammation on the Hippocampus—A Mini Review
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
46. Current utilization trend of immortalized mast cell lines in allergy research: a systematic review
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
47. The application of seaweed-based food products for ketogenic diet: Opportunities and prospects
    Journal type: Citation-Indexed Journal - ESCI
48. Mcl‑1 is an important target protein for kaempferol from persimmon leaves in sensitizing ABT‑199 to induce apoptosis in hepatoma cancer cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
49. Polyethylene microplastics disrupt renal function, mitochondrial bioenergetics, redox homeostasis, and histoarchitecture in Wistar rats
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
PENERBITAN
2025
USP14 inhibits sensitization-mediated degradation of KDM4D to epigenetically regulate dendritic cell tolerogenic capacity and mitigates airway allergy
2024
Acquisition of aseptic techniques using virtual reality: A randomized trial on performance, emotion and experience
2024
Student acceptance towards AsepticTech VR: a teaching and learning tool for cell and tissue culture aseptic techniques
2024
Oral and Topical Administration of a Geranyl Acetophenone Attenuates DNCB-induced Atopic Dermatitis-like Skin Lesions in BALB/c Mice
2024
Menopause-associated depression: Impact of Oxidative Stress and Neuroinflammation on the Central Nervous System – A Review
2024
Flavonoid diversity and roles in the lipopolysaccharide-mediated inflammatory response of monocytes and macrophages
2024
A synthetic curcumin?like diarylpentanoid analog inhibits rhinovirus infection in H1 hela cells via multiple antiviral mechanisms
2024
Neuroprotective effects of Gypenosides: A review on preclinical studies in neuropsychiatric disorders
2024
Ameliorative effect of ?-tocopherol and tocotrienol-rich palm oil extract on menopausal-associated mood disorder in ovariectomised mice
2023
Insight parameter drug design for human ?- tryptase inhibition integrated molecular docking, QSAR, molecular dynamics simulation, and pharmacophore modelling studies of ?-keto- [1,2,4]-oxadiazoles
2023
House dust mite allergy in Malaysia: review of research gaps in the current scenario and the way forward
2023
The Anti-Allergic Potential of Stingless Bee Honey from Different Botanical Sources via Modulation of Mast Cell Degranulation
2023
Clinacanthus nutans Aqueous Extract Exerts Anti-Allergic Activity in Preclinical Anaphylactic Models via Alternative IgG Pathway
2023
Insight parameter drug design for human ?-tryptase inhibition integrated molecular docking, QSAR, molecular dynamics simulation, and pharmacophore modelling studies of ?-keto-[1,2,4]-oxadiazoles
2022
Sensitization effect of Kaempferol from Persimmon leaves on Hepatoma Cells with ABT-199 resistance and its molecular mechanisms
2022
Ameliorative Effect of Tocotrienols on Perimenopausal-Associated Osteoporosis—A Review
2022
MANAGEMENT OF ATOPIC DERMATITIS VIA ORAL AND TOPICAL ADMINISTRATION OF HERBS IN MURINE MODEL: A SYSTEMATIC REVIEW
2022
Rhinovirus-Induced Cytokine Alterations with Potential Implications in Asthma Exacerbations: A Systematic Review and Meta-Analysis
2022
Anti-allergic Properties of Propolis: Evidence from Preclinical and Clinical Studies
2022
Alcohol Withdrawal and the Associated Mood Disorders—A Review
2021
Pharmacological Properties of 2,4,6-Trihydroxy-3-Geranyl Acetophenone and the Underlying Signaling Pathways: Progress and Prospects
2021
The Potential Use of Honey as a Remedy for Allergic Diseases: A Mini Review
2021
Zerumbone Attenuates House Dust Mite-Induced Epithelial Barrier Dysfunction in 16HBE14o- Cells
2021
2,4,6-Trihydroxy-3-Geranyl Acetophenone Suppresses Vascular Leakage and Leukocyte Infiltration in Lipopolysaccharide-Induced Endotoxemic Mice
2020
Differential regulation of LPS-mediated VE-cadherin disruption in human endothelial cells and the underlying signaling pathways: A mini review.
2020
A Review of Malaysian Herbal Plants and Their Active Constituents with Potential Therapeutic Applications in Sepsis
2020
Clinacanthus nutans Aqueous Extract Suppresses the Release of Histamine and ?-hexosaminidase in In Vitro Model of IgE-Mediated Mast Cell Degranulation
2019
Effect of Diarylpentanoid Analogues on Lipopolysaccharide- Induced Interleukin-6 and Interleukin-8 Gene Expression in Airway Inflammation
2019
Mast cell stabilizing effect of a geranyl acetophenone in dengue virus infection using in vitro model of DENV3-induced RBL-2H3 cells
2019
IgG-Mediated Anaphylaxis: Biomarker Identification via Meta-Analysis
2018
Major Bioactive Compounds in Essential Oils Extracted from the Rhizomes of Zingiber zerumbet (L) Smith: A Minireview on the AntiAllergic and Immunomodulatory Properties
2017
Anti-allergic activity of 2,4,6-trihydroxy-3-geranylacetophenone (tHGA) via attenuation of IgE-mediated mast cell activation and inhibition of passive systemic anaphylaxis
2017
LAT is Essential for the Mast Cell Stabilising Effect of tHGA in IgE-Mediated Mast Cell Activation
2016
Barrier protective effects of 2,4,6-trihydroxy-3-geranyl acetophenone on lipopolysaccharides-stimulated inflammatory responses in human umbilical vein endothelial cells
2015
Inhibition of epithelial CC-family chemokine synthesis by the synthetic chalcone DMPF-1 via disruption of NF-kB nuclear translocation and suppression of experimental asthma in mice
2014
Inhibition of epithelial CC-family chemokine synthesis by the synthetic chalcone DMPF-1 via disruption of NF-eB nuclear translocation and suppression of experimental asthma in mice
2012
Development and Validation of a Bioanalytical Method for Quantification of 2,6-Bis-(4-Hydroxy-3-Methoxybenzylidene)-Cyclohexanone (BHMC) in Rat Plasma