PROFESIONAL

Viral vectors: design and delivery for small RNA
WC Koh, K Yusoff, AAL Song, N Saad, SL Chia
Journal of Medical Microbiology 74 (2), 001972

Characterization of the host specificity of the SH3 cell wall binding domain of the staphylococcal phage 88 endolysin
HY Tham, LC Chong, M Krishnan, AM Khan, SB Choi, T Tamura, K Yusoff, ...
Archives of Microbiology 207 (2), 47

Development of a recombinant non-replicating Newcastle disease virus
PS Cheow, TK Tan, AAL Song, K Yusoff, SL Chia
Avian Pathology 54 (1), 149-157

Different Combinations of Nitrogen and Carbon Sources Influence the Growth and Postbiotic Metabolite Characteristics of Lactiplantibacillus plantarum Strains …
Q Zheng, SL Chia, N Saad, AAL Song, TC Loh, HL Foo
Foods 13 (19), 3123

Orally dissolving yoghurt strip: a new approach in delivery of probiotics
LAK Saleena, KL Nyam, YA Yusof, AAL Song, LLA In, LP Pui
Journal of Food Measurement and Characterization 18 (9), 8110-8119

Development of optimized functional clove fortified probiotic yoghurt
LAK Saleena, AAL Song, YA Yusof, LLA In, NK Lin, LP Pui
Journal of Food Science and Technology 61 (7), 1343-1354

Effect of Domain Manipulation in the Staphylococcal Phage Endolysin, Endo88, on Lytic Efficiency and Host Range
M Krishnan, HY Tham, WAK Wan Nur Ismah, K Yusoff, AAL Song
Molecular Biotechnology, 1-9

Genome mining of Lactiplantibacillus plantarum PA21: insights into its antimicrobial potential
SL Isaac, AZ Abdul Malek, NS Hazif, FS Roslan, A Mohd Hashim, ...
BMC genomics 25 (1), 571

Recombinant lactococcal-based oral vaccine for protection against Streptococcus agalactiae infections in tilapia (Oreochromis niloticus)
KY Wong, MHMM Khair, AAL Song, MJ Masarudin, JY Loh, CM Chong, ...
Fish & Shellfish Immunology 149, 109572

Characterization and shelf-life study of functional yoghurt based oral strip in polypropylene–aluminium/LLDPE blister pack
LAK Saleena, KL Nyam, YA Yusof, AAL Song, LLA In, LP Pui
Journal of Food Measurement and Characterization 18 (5), 3771-3782

Development of clove extract-fortified functional yoghurt powder using spray: drying
LAK Saleena, YA Yusof, AAL Song, LLA In, KL Nyam, LP Pui
Journal of Food Measurement and Characterization 18 (4), 2776-2796

A newly isolated Pseudomonas otitidis phage, vB_PotS-PotUPM1 from tilapia in Malaysia
AN Tee, MHMM Khair, CM Chong, MAM Shaufi, K Yusoff, HC Yam, ...
Aquaculture Reports 34, 101883

Effects of Individual and Combined Fermentation Factors on Antimicrobial Activity of Nisin by Lactococcus lactis ATCC 11454
NH Mohd Rasid, N Abdul Halid, AAL Song, S Sabri, N Saari, H Hasan
Molecular biotechnology 65 (6), 861-870

Effect of Secretion Efficiency of Mutant KRAS Neoantigen by Lactococcus lactis on the Immune Response of a Mucosal Vaccine Delivery Vehicle Targeting …
NAR Alias, WPY Hoo, PY Siak, SS Othman, NB Mohammed Alitheen, ...
International Journal of Molecular Sciences 24 (10), 8928

Comprehensive characterization of a Streptococcus agalactiae phage isolated from a tilapia farm in Selangor, Malaysia, and its potential for phage therapy
MHMM Khair, AN Tee, NF Wahab, SS Othman, YM Goh, MJ Masarudin, ...
Pharmaceuticals 16 (5), 698

Vandachostylis ‘Sri-Siam’: an intergeneric hybrid with superior qualities as evidenced by its biochemical fragrance and transcriptome profiles
AR Mohd-Hairul, J Ong-Abdullah, AAL Song, HL Foo, P Namasivayam, ...
Journal of Plant Biochemistry and Biotechnology 31 (4), 965-968

Optimization of Signal Peptide via Site-Directed Mutagenesis for Enhanced Secretion of Heterologous Proteins in Lactococcus lactis
NAR Alias, AAL Song, NB Alitheen, RA Rahim, SS Othman, LLA In
International Journal of Molecular Sciences 23 (17), 10044

Endolysins against Streptococci as an antibiotic alternative
KY Wong, MH Megat Mazhar Khair, AAL Song, MJ Masarudin, CM Chong, ...
Frontiers in Microbiology 13, 935145

Chandran, C., Tham, H. Y., Rahim, R. A., Lim, S. H. E., Yusoff, K., & Song, A. A. L. (2022). Lactococcus lactis secreting phage lysins as a potential antimicrobial against multi-drug resistant Staphylococcus aureus. PeerJ, 10, e12648.

Shaili, N.A., Song, A.A., Othman, S.S., In L.L.A., Raha, A.R. (2022). Engineering Lactococcus lactis as cell factory for the production of plant anti-cancer compounds, limonene and perillyl alcohol. Sains Malaysiana 51(1): 95-105.

Song, A.A., Sabri, S. and Ismail S., (2022). Service learning in microbiology during the pandemic: a Malaysian perspective. Malaysian Journal of Microbiology 18(2): 128-135

Ashaari, N. S., Sabri, S., Lai, K. S., Song, A. A. L., Abdul Rahim, R., & Ong Abdullah, J. (2021). Kinetic studies and homology modeling of a dual-substrate linalool/nerolidol synthase from Plectranthus amboinicus. Scientific reports, 11(1), 1-16.

Yeong, M. Y., Cheow, P. S., Abdullah, S., Song, A. A. L., Lei-Rossmann, J., Tan, T. K., ... & Chia, S. L. (2021). Development of a T7 RNA polymerase expressing cell line using lentivirus vectors for the recovery of recombinant Newcastle disease virus. Journal of virological methods, 291, 114099.

Teo, M. Y. M., Ng, J. J. C., Fong, J. Y., Hwang, J. S., Song, A. A. L., Lim, R. L. H., & In, L. L. A. (2021). Development of a single-chain fragment variable fused-mutant HALT-1 recombinant immunotoxin against G12V mutated KRAS colorectal cancer cells. PeerJ, 9, e11063.

Siak, P. Y., Wong, K. Y., Song, A. A. L., Rahim, R. A., & In, L. L. A. (2021). K-Ras Peptide Mimotope Induces Antigen Specific Th1 and B-Cell Immune Responses against G12A-Mutated K-Ras Antigen in Balb/c Mice. Vaccines, 9(3), 195.

Nakkarach, A., Foo, H. L., Song, A. A. L., Mutalib, N. E. A., Nitisinprasert, S., & Withayagiat, U. (2021). Anti-cancer and anti-inflammatory effects elicited by short chain fatty acids produced by Escherichia coli isolated from healthy human gut microbiota. Microbial Cell Factories, 20(1), 1-17.

Assafiri, O., Song, A. A. L., Tan, G. H., Hanish, I., Hashim, A. M., & Yusoff, K. (2021). Klebsiella virus UPM2146 lyses multiple drug-resistant Klebsiella pneumoniae in vitro and in vivo. Plos one, 16(1), e0245354.

Mohd-Hairul, A. R., Ong Abdullah, J., Song, A. A. L., Foo, H. L., Namasivayam, P., & Rahim, R. A. (2020). Volatile constituents and floral transcriptome analyses provide new insights into fragrance biosynthesis of Vanda ‘Tan Chay Yan’. Plant Biosystems-An International Journal Dealing with all Aspects of Plant Biology, 1-8.

Tham, H. Y., Song, A. A., Yusoff, K., & Tan, G. H. (2020). Effect of different cloning strategies in pET-28a on solubility and functionality of a staphylococcal phage endolysin. BioTechniques, 69(3), 161-170.

Ashaari, N. S., Ab. Rahim, M. H., Sabri, S., Lai, K. S., Song, A. A. L., Abdul Rahim, R., ... & Ong Abdullah, J. (2020). Functional characterization of a new terpene synthase from Plectranthus amboinicus. PloS one, 15(7), e0235416.

Nakkarach, A., Foo, H. L., Song, A. A. L., Nitisinprasert, S., & Withayagiat, U. (2020). Promising discovery of beneficial Escherichia coli in the human gut. 3 Biotech, 10, 1-14.

Lee, C. Y., Song, A. A. L., Loh, T. C., & Rahim, R. A. (2020). Effects of lysine and methionine in a low crude protein diet on the growth performance and gene expression of immunity genes in broilers. Poultry science, 99(6), 2916-2925.

Roslan, A. M., Kamil, A. M., Chandran, C., Song, A. A. L., Yusoff, K., & Rahim, R. A. (2020). Secretion of recombinant xylanase in Lactococcus lactis using signal peptides Usp45 and Spk1. Biotechnology letters, 42(9), 1727-1733.

Koko, I., Song, A. A. L., Masarudin, M. J., & Rahim, R. A. (2019). Engineering integrative vectors based on phage site-specific recombination mechanism for Lactococcus lactis. BMC biotechnology, 19(1), 1-12.

Chan, C. J., Yong, Y. S., Song, A. A. L., Abdul Rahim, R., In, L. L. A., & Lim, R. L. H. (2020). Lactococcus lactis harbouring Ara h 2.02 alleviates allergen‐specific Th2‐associated responses in sensitized mice. Journal of applied microbiology, 128(3), 862-874.

Cheow, P. S., Tan, T. K., Song, A. A. L., Yusoff, K., & Chia, S. L. (2019). An improved method for the rescue of recombinant Newcastle disease virus. BioTechniques, 68(2), 96-100.

Mahizan, N. A., Yang, S. K., Moo, C. L., Song, A. A. L., Chong, C. M., Chong, C. W., ... & Lai, K. S. (2019). Terpene Derivatives as a Potential Agent against Antimicrobial Resistance (AMR) Pathogens. Molecules, 24(14), 2631.

Azlan, H.S.A.N., Hamid, M. and Song A.A. (2019). Characterization of Bacteriophage against Enterococcus faecium Resistant to Vancomycin Isolated from Chicken Skin. Asian Food Science Journal, 10(1): 1-14.

Mustafa, A. D., Kalyanasundram, J., Sabidi, S., Song, A. A. L., Abdullah, M., Rahim, R. A., & Yusoff, K. (2019). Recovery of recombinant Mycobacterium tuberculosis antigens fused with cell wall-anchoring motif (LysM) from inclusion bodies using non-denaturing reagent (N-laurylsarcosine). BMC Biotechnology, 19(1), 27.

Tan ZQ, Leow HW, Lee DCW, Karisnan K, Song AA, Mai CW, Yap WS, Lim SWE and Lai KS. (2019). Co-culture systems for the production of secondary metabolites: current and future prospects. The Open Biotechnology Journal, 13, 18-26.

Mustafa, A. D., Kalyanasundram, J., Sabidi, S., Song, A. A., Abdullah, M., Abdul Rahim, R., & Yusoff, K. (2018). Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice. BMC Biotechnology, 18(1), 63. doi:10.1186/s12896-018-0461-y

Ng A.W.R., Tan P.J., Hoo, W.P.Y, Liew D.K., Teo,M.Y.M., Siak P.Y., Ng S.M., Tan E.W., Rahim A.R., Lim, R.L.H., Song A.L.A., In L.A.L. 2018. In silico-guided sequence modifications of K-ras epitopes improve immunological outcome against G12V and G13D mutant KRAS antigens. Peer J. Jul 20;6: e5056

Mat Isa, N., Abdul Mutalib, N.E., Alitheen, N.B., Song, A.A., and Rahim, A.R. 2017. Cell-wall treated Lactococcus lactis increases the plasmid transfer efficiency of internal ribosome entry site-incorporated lactococcal bicistronic vector into DF1 cells. Journal of Molecular Microbiology and Biotechnology 27:246-251.

Song, A.A., In, L.A.L., Lim, S.H.E. and Rahim, A.R. 2017. A review on Lactococcus lactis: From food to factory. Microbial Cell Factories. 16:55

Siaw, X.J.S., Jee, P., Song, A.A., Chang, L., Khatijah, Y., Sazaly, A.B. and Raha, A.R. 2016. Oral administration of Lactococcus lactis harbouring pandemic H1N1 2009 Haemagglutinin1 and nisP anchor fusion protein elevates anti-HA1 sIgA levels in mice. Biotechnology Letters. 38(5):793-799

Kalyasundram., J., Chia, S.L., Song A.A., Raha, A.R., Young, H. and Khatijah, Y. 2015. Surface display of glycosylated Tyrosinase related protein-2, TRP-2 tumour antigen on Lactococcus lactis. BMC Biotechnology. 15:113

Jalilsood, T., Baradaran, A., Song, A.A., Foo, H.L., Mustafa, S., Saad, W.Z., Yusoff, K. and Rahim, A.R. 2015. Inhibition of pathogenic and spoilage bacteria by novel biofilm-forming Lactobacillus isolate: a potential host for the expression of heterologous host. Microbial Cell Factories. 14:96.

Lau SE, Mazumdar P, Hee TW, Song ALA, Othman RY and Harikrishna JA. 2015. Crude extracts of bacterially expressed dsRNA protect orchid plants against cymbidium mosaic virus during transplantation from in vitro culture. J Horti Sci Biotechnol. 89(5): 569-576.

Song, A.A., Abdullah, J.O., Abdullah, M.P., Shafee, N., Othman, R., Noor, N.M. and Rahim, A.R. 2014. Engineering the lactococcal mevalonate pathway for increased sesquiterpene production. FEMS Microb Lett. 355: 177-184.

Maidin, S.T., Song, A.A., Sieo, C.C., Yusoff, K.M. and Raha, A.R. 2014. Construction of a Novel Inducible Expression Vector for Lactococcus lactis M4 and Lactobacillus plantarum Pa21. Plasmid 74: 32-38.

Mutalib, N.E.A., Isa, N.M., Alitheen, N.B., Song, A.A., and Rahim, A.R. 2014. IRES-Incorporated lactococcal bicistronic vector for target gene expression in a eukaryotic system. Plasmid. 73:26-33.

Song, A.A., Abdullah, J.O., Abdullah, M.P., Shafee, N., Othman, R. Normah, M.N., Tan, E.F. and Raha, A.R. 2012. Overexpressing HMGR in the lactococcal mevalonate pathway for heterologous plant isoprenoid production. PlosOne. 7(12): e52444

Song, A.A., Abdullah, J.O., Abdullah, M.P., Shafee, N., Rahim, R.A. 2012. Functional expression of an orchid fragrance gene in Lactococcus lactis. Int. J. Mol. Sci. 13 (2): 1582-1597.

Harikrishna, J.A., Miin, D.O.J., Lian, A.S.A., Dzulkurnain, A., Othman, R.Y., Hoon, L.S. (2010). Biotechnological approaches to protection against cymbidium mosaic virus. Asia-Pacific Journal of Molecular Biology and Biotechnology. Volume 18, Issue 1, 2010, Pages 181-184 (SCOPUS-Cited Publication)