PROFILE
UPM's Staff Profile
YBHG. PROFESOR DR. MD ZUKI BIN ABU BAKAR @ ZAKARIA
PROFESSOR
FACULTY OF VETERINARY MEDICINE
zuki@upm.edu.my
PROFESSIONAL
NAME :
(Ybhg. Profesor Dr.) MD ZUKI BIN ABU BAKAR @ ZAKARIA
POST :
PROFESSOR
ENTITY :
FACULTY OF VETERINARY MEDICINE
FIELD OF SUPERVISION
ANATOMY AND HISTOLOGY / ANIMAL PRODUCTION / CANCER BIOLOGY AND ONCOLOGY / MEDICAL BIOTECHNOLOGY / NANOMEDICINE
PUBLICATION
2025
Bioactivity evaluation of Polygonum minus and identification of synergistic phytochemicals with 5-fluorouracil for colon cancer treatment.
2025
Recent progress in calcium carbonate nanoparticles for cancer therapy: design strategies and clinical prospects.
2025
Exploring the anti-colon cancer potential of Polygonum minus: Integrating in vitro and in silico studies.
2025
Plant Foods and Their Bioactives as Dietary Enhancers for Colon Cancer Treatment with 5-Fluorouracil.
2024
Fluorescent imaging and bio-cellular uptake assessment of gold-near infrared dye conjugated cockle shell calcium carbonate nanoparticles
2024
Exploring the Therapeutic Potential of 5-Fluorouracil-Loaded Calcium Carbonate Nanoparticles Combined with Natural Compound Thymoquinone for Colon Cancer Treatment
2024
Unveiling Drimenol: A Phytochemical with Multifaceted Bioactivities
2024
5-Fluorouracil in Combination with Calcium Carbonate Nanoparticles Loaded with Antioxidant Thymoquinone against Colon Cancer: Synergistically Therapeutic Potential and Underlying Molecular Mechanism
2024
Cytotoxicity and Apoptotic DNA Fragmentation Evaluation of Ethanolic Extract of Phyllanthus niruri L. in Vero and Primary Feline Testicular Cells
2024
Polygonum minus: A tropical medicinal herb with vast applications in food, agricultural, and medicinal fields
2023
Edible bird's nest effectively attenuates atherosclerosis through modulation of cholesterol metabolism via activation of PPARy/LXRa Signaling pathway in vivo
2021
LC-MS/MS Proteomic Study of MCF-7 Cell Treated with Dox and Dox-Loaded Calcium Carbonate Nanoparticles Revealed Changes in Proteins Related to Glycolysis, Actin Signalling, and Energy Metabolism
2021
Cardiomyocyte Morphology with Repeated Doses of Cockle shell derived Calcium Carbonate Nanoparticle loaded with Doxorubicin
2020
Biocompatibility Assessment and Cellular Uptake of Conjugated Gold-Cockle Shell Derived Calcium Carbonate Nanoparticles for Fluorescent Imaging
2020
Combine Drug Delivery of Thymoquinone-Doxorubicin by Cockle Shell derived pH-sensitive Aragonite CaCO3 Nanoparticles
2020
Cockle shell-derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells
2020
Cockle Shell-Derived Aragonite CaCO3 Nanoparticles for Co-Delivery of Doxorubicin and Thymoquinone Eliminates Cancer Stem Cells
2019
Ultrastructural Changes and Antitumor Effects of Doxorubicin/ Thymoquinone-Loaded CaCO3 Nanoparticles on Breast Cancer Cell Line
2019
Modified methods of nanoparticles synthesis in pH sensitive Nano-carriers production for doxorubicin delivery on MCF-7 breast cancer cell-line
2019
In vivo evaluation of anticancer efficacy of drug loaded cockle shell?derived aragonite nanoparticles
2019
Characterization and In Vitro evaluation of a novel coated nanocomposite porous 3D scaffold for bone repair
2019
Curcumin Attenuates Lead-Induced Cerebellar Toxicity in Rats via Chelating Activity and Inhibition of Oxidative Stress
2018
In Vivo Evaluation of The Novel Nanocomposite Porous 3D Scaffold in a Rabbit Model
2018
Fabrication, Characterisation and Cytotoxicity of Spherical-Shaped Conjugated Gold-Cockel Shell Derived Calcium Carbonate Nanoparticles for Biomedicial Applications
2018
Novel synthesis of nanoparticles from cockle shells via mechanical method for cytarabine drug release
2018
In vivo evaluation of anticancer efficacy of drug loaded cockle shell-derived aragonite nanoparticles
2018
Fabrication, Characterization and Cytotoxicity of Spherical-Shaped Conjugated Gold-Cockle Shell Derived Calcium Carbonate Nanoparticles for Biomedical Applications
2018
TOXICITY AND SAFETY EVALUATION OF DOXORUBICIN LOADED COCKLE SHELLED DERIVED CALCIUM CARBONATE NANOPARTICLE IN DOGS
2017
Preparation and characterization of cockle shell aragonite nanocomposite porous 3D scaffolds for bone repair
2017
novelty to synthesis nanoparticles from cockle shall via mechanical method to delivery
2017
Surface-functionalized cockle shell–based calcium carbonate aragonite polymorph as a drug nanocarrier
2017
Formulation of a Sustained Release Docetaxel Loaded Cockle Shell-Derived Calcium Carbonate Nanoparticles Against Breast Cancer
2017
Development of Cockleshell (Anadara granosa) Derived CaCO3 Nanoparticle for Doxorubicin Delivery
2017
In vitro evaluation of a novel pH sensitive drug delivery system based cockle shell-derived aragonite nanoparticles against osteosarcoma
2017
Evaluation of in vitro efficacy of docetaxel-loaded calcium carbonate aragonite nanoparticles (DTX-CaCO3NP) on 4T1 mouse breast cancer cell line
2017
Synthesis, characterization, and cytocompatibility of potential cockle shell aragonite nanocrystals for osteoporosis therapy and hormonal delivery
2016
Effects of enriching goat meat with n − 3 polyunsaturated fatty acidson meat quality and stability
2016
Development of nanoantibiotic delivery system using cockle shell-derived aragonite nanoparticles for treatment of osteomyelitis
2016
Antibacterial activity of Ciprofloxacin-Encapsulated Cockle Shells Calcium Carbonate (Aragonite) NanoParticles and its Biocompatability in Macrophage J774A.1
2016
The Relationship between Dietary Calcium Intakes Contain in Goats? Feed with Calcium Serum Concentration in Pregnant Boer Goats
2014
Biocompatibility of Bio Based Calcium Carbonate Nanocrystals Aragonite Polymorph on NIH 3T3 Fibroblast cell line
2014
Changes in Fatty Acid Composition and Distribution of N-3 Fatty Acids in Goat Tissues Fed Different Levels of Whole Linseed
2014
Development and Characterization of Novel Porous 3D Alginate-Cockle Shell Powder Nanobiocomposite Bone Scaffold
2014
In Vitro Ultrastructural Changes of MCF-7 for Metastasise Bone Cancer and Induction of Apoptosis via Mitochondrial Cytochrome C Released by CaCO3/Dox Nanocrystals
2014
The Enzyme Activities of Pancreas and Small Intestinal Contents in the Malaysian Village Chicken and Broiler Strains
2014
Osteoblasts Growth Behaviour on Bio-Based Calcium Carbonate Aragonite Nanocrystal
2013
Effects of Dietary N-3 Fatty Acids on Growth Performance, Apparent Digestibility and Carcass Characteristics of Crossbred Boer Goat under Tropical Conditions
2013
Synthesis and Characterisation of Calcium Carbonate Aragonite Nanocrystals from Cockle Shell Powder (Anadara granosa)
2013
In vitro delivery and controlled release of doxorubicin for targeting osteosarcoma bone cancer
2013
A novel catalytic method for the synthesis of spherical aragonite nanoparticles from cockle shells
2013
Reproductive characteristic of the female laboratory rat
2013
A novel method for the synthesis of calcium carbonate (aragonite) nanoparticles from cockle shells
2013
A pH-Sensitive, Biobased Calcium Carbonate Aragonite Nanocrystal as a Novel Anticancer Delivery System
2012
Effects of elevated ambient temperature on embryo implantation in rats.
2012
Effects of elevated ambient temperature on reproductive outcomes and offspring growth depend on exposure time.
2012
Gelam (Melaleuca spp.) Honey-Based Hydrogel as BurnWound Dressing
2012
Honey Hydrogel Dressing to Treat Burn Wound in Rats-A Preliminary Report
2012
Histomorphometric evaluation of small intestinal mucosa of red jungle fowl and commercial broiler from one day to four months of age
2012
Facile synthesis of calcium carbonate nanoparticles from cockle shells
2011
Morphological study of the lingual papillae in the barking deer, Muntiacus muntjak
2011
Effect of n-3 and n-6 fatty acid supplementation on fetal, gestation and parturition in pregnant Sprague Dawley rats
2011
Effects of Momordica charantia aqueous extract on renal histopathological changes associated with streptozotocin-induced diabetes mellitus type II in neonatal rats.
2011
Effects of Momordica Charantia on Pancreatic Histopathological Changes Associated with Streptozotocin-Induced Diabetes in Neonatal Rats
2011
Immunohistochemical study of endocrine cells in the gastrointestinal tract of the barking deer, Muntiacus muntjak
2011
Sea cucumber (Stichopus hermanii) based hydrogel to treat burn wounds in rats
2011
Characterisation of calcium carbonate and its polymorph from cockle shells (Anadara granosa)
2011
Antioxidant and antihyperglycaemic effects of an aqueous extract from Momordica charantia fruit in a type II diabetic rat model
2011
Activities of Amylase, Trypsin and Chymotrypsin of pancreas and small intestinal contents in the Red Jungle Fowl and broiler breed
2011
Histological changes in the endometrial of pregnant spraque-dawley rats under supplementation levels of n-6:n-3 fatty acid ratio
2011
Carcass composition in three different breeds of chicken and their corelation with growth performance
2011
Effect of dietary n-6 to n-3 polyunsaturated fatty acid ratio on prostaglandin plasma levels and genes expression peroxisome proliferator-activated receptor (PPAR) in pregnant Spraque Dawley rats
2011
Morphological study of the infraorbital gland of the male barking dear, muntiacus muntjak
2011
Sea cucumber (Stichopus hermanii) based hydrogel to treat burn wounds in rats
2011
Morphological study of the infraorbital gland of the male barking deer, muntiacus muntjak
2011
Determinatin of antioxidant activity in methanolic and chloroformic extracts of momordica charantia
2011
A comparative study of lyophilized bovine pericardium and tunica parietalis vaginalis for repair of large abdominal wall defetcs in a rabbit model
2010
Morphological study of pancreatic duct in red jungle fowl
2010
Histological study of the parotid and mandibular glands of barking deer (Muntiacus muntjak) with special reference to the distribution of carbohydrate content
2010
Growth evaluation of selected digestive organs from day one to four months post-hatch in two breeds of chickens known to differ greatly in growt rate.
2010
Tissue engineering approach to repair abdominal wall defects using cell-seeded bovine tunica vaginalis in a rabbit model
2010
Effects of varying levels of n-6:n-3 fatty acid ratio on plasma fatty acid composition and prostanoid synthesis in pregnant rats
2010
Light and scanning electron microscopy of the intestine of the young Red Jungle fowl (Gallus gallus)
2010
The effects of momordica charantia on the liver in streptozotocin-induced diebetes in neonatal rats.
2009
In vitro study of the follicular and luteal phases susceptibility to E. coli adhesion in ewes
2009
Distribution of Lectin-Bindings in the Testis of the Lesser Mouse Deer, Tragulus javanicus
2009
In vitro study on the susceptibility of E coli adhesion in ewes during follicular and luteal phases of the oestrous cycle
2009
Secretory IgA concentrations and plasma cell count changes associated with the estrus cycle in ewes