A
PROFILE
Laman Web Staf UPM
YBHG. PROFESOR DR. TS. CHEAH YOKE KQUEEN
TIMBALAN DEKAN (SISWAZAH,JIM&PENJANAAN PENDAPATAN)
FAKULTI PERUBATAN DAN SAINS KESIHATAN
ykcheah@upm.edu.my
Laman Web UPM
PROFILE
ykcheah
BM
EN

PROFESIONAL

Felo Akademi Sains Malaysia.
Ahli Majlis untuk Bidang Sains Bioperubatan (Majlis Profesion Kesihatan Bersekutu Malaysia (MPKBM)) 2019 – 2023.
Penasihat kepada Persatuan Sains Bioperubatan Malaysia
Presiden Persatuan Graduan Bioperubatan Kuala Lumpur dan Selangor (BIOMEDKL).
Presiden Alumni 'Korea Government Scholarship Programme' (myGKS).
Chartered Scientist Institute of Biomedical Science, UK.
Chartered Biologist Royal Society of Biology, UK.
Fellow of the Royal Society of Chemistry, UK.
Fellow of the Royal Society of Biology, UK.
Fellow of the Institute of Biomedical Science, UK.
Penasihat Teknikal Diagnostik Molekul (Ramsay Sime Darby Medical Centre).
Ketua Editor untuk Life Sciences, Medicine and Biomedicine.
NAMA :
(Ybhg. Profesor Dr. Ts.) CHEAH YOKE KQUEEN
JAWATAN PENTADBIRAN :
TIMBALAN DEKAN (SISWAZAH,JIM&PENJANAAN PENDAPATAN)
JAWATAN HAKIKI :
PROFESOR
ENTITI :
FAKULTI PERUBATAN DAN SAINS KESIHATAN

BIDANG PENYELIAAN
BIOINFORMATICS AND SYSTEM BIOLOGY / CANCER BIOLOGY AND ONCOLOGY / CELL BIOTECHNOLOGY / GENETICS / MOLECULAR MEDICINE


LATARBELAKANG PENDIDIKAN
2022
Sarjana Pentadbiran Perniagaan
2018
Diploma Lepasan Ijazah dalam Bioinformatik
2006
PhD (Kejuruteraan Genetik dan Biologi Molekul)
2001
MSc (Biologi Molekul)
1998
BSc (Kepujian) (Sains Bioperubatan)
PENGALAMAN KERJA
2022
Pejabat Timbalan Dekan (Siswazah, Jaringan Industri & Masyarakat dan Penjanaan Pendapatan), Faculty of Medicine and Health Sciences, UPM
2020
Ketua Jabatan (Jabatan Sains Bioperubatan), Fakulti Perubatan dan Sains Kesihatan, UPM
2017
Timbalan Pengarah, Pusat Perhubungan dan Jaringan Industri, UPM
Ketua Unit Biologi Molekul & Bioinformatik, Jabatan Sains Bioperubatan, Fakulti Perubatan dan Sains Kesihatan, UPM
KEMAHIRAN
Perubatan Molekul
Diagnostic Molekul
Bioinformatik
Sains Bioperubatan
Penemuaan Ubatan
Biologi Molekul
Biologi Kanser
Mikrobiologi Molekul
Genetik
Bioteknologi Perubatan
PROJEK
2023
Pengenalpastian Biomarker Kanser Payudara miRNA bukan invasif di kalangan Wanita dengan mamogram yang tidak normal sebagai Alat Diagnostik Awal
2022
Isolasi dan Pencirian Fungsi Mitokondria Sel Stem Kanser Kepala dan Leher
2020
Peranan mikroRNA dan Mitokondria dalam Sel Stem Kanser dan Karsinogenesis Kanser Kepala dan Leher
2018
Aktiviti Antimikrob Kompleks Emas dan Pendekatan Gabungannya terhadap Multi-Drug Resistant MRSA
2017
Pencirian dan Pengenalpastian Sebatian Bioaktif Terhasil daripada Bakteria Endofit Tumbuhan Ubat Malaysia Terpilih
2015
Salmonella Agona Sasaran Tumor untuk Tumor Mamari Anjing Yang Berkembang Secara Spontan
2015
Pengasingan dan Pencirian Sebatian Antikanser Novel Dihasilkan oleh Barrientosiimonas humi gen. nov., sp. nov., Actinobacterium Diasingkan dari Pulau Barrientos, Antartika Menentang Kanser Kolorektal
2015
Pencirian Litik Kuantitatif Bakteriofaj Diasingkan daripada Persekitaran Terhadap Vibrio parahaemolyticus
2014
Penerokaan peranan Multifungsi interaksi MiRNA dengan sebatian organologam, sel dan fenomik berhubung dengan kanser (Penyelaras Program TRGS)
2014
Memahami peranan miRNA pada pelbagai sel kanser melalui selulomik integratif dan fenomik untuk diagnostik, terapeutik dan prognostik.
2014
Meneroka Peranan MikroRNA Peredaran Novel dan Polimorfisma Nukleotida Tunggal sebagai Biomarker Diagnostik, Prognostik dan Ramalan dalam Hubungan dengan Penyakit Jantung Iskemia
2014
Pengenalpastian dan Potensi Bioaktif Endofit yang Diasingkan daripada Strobilanthes cripus, tumbuhan ubatan tempatan di Malaysia
2012
Penambahbaikan secara kejuruteraan genetik strain Salmonella enterica serovar Agona (knock out) sebagai agen antitumor yang berpotensi
2011
Pembangunan kaedah 'High Resolution Melt' dalam Pengesanan Profil Mutasi Reseptor Faktor Pertumbuhan Epidermis Unik untuk Kanser Paru-paru
2011
Isolasi, Pengenalpastian, Pencirian dan Bioprospek Actinomycetes dari Pulau Barrientos, Antartika
2011
Pemprofilan Antigen CD pada Kanser Kepala dan Leher untuk Pembangunan Biomarker Diagnostik
2011
Penemuan Novel mikroRNA yang Berkaitan dengan Kanser Kepala dan Leher untuk Pembangunan Alat Diagnostik Awal dan Sasaran Terapeutik
2008
Penerokaan MikroRNA dalam Peringkat Berbeza Kanser Kolorektal dalam Pencarian Penanda Bio dan Alat Terapeutik Berpotensi
2007
Pembangunan Biosensor DNA Berasaskan Nanopartikel untuk Pengesanan Organisma Terubahsuai Genetik Menyasarkan Gen Rintangan Serangga dan Gen Rintangan Herbisida Secara serentak
2006
Penyiasatan Salmonella enterica sebagai vektor antikanser baru (novel)
ANUGERAH DAN PENCAPAIAN
2022
The Malaysia Book of Records
Top Research Scientist Malaysia 2017
BIDANG PENGKHUSUSAN
Perubatan Molekul
Genetik
Diagnostik Molekul
Penemuan ubatan
Biologi Molekul
Bioinformatik
Bioteknologi Perubatan
Biologi Kanser
Mikrobiologi Molekul
Sains Bioperubatan
MINAT PENYELIDIKAN
Perubatan Molekul
Penemuan ubatan
Genetik
Bioinformatik
Bioteknologi Perubatan
Mikrobiologi molekul
Biologi Kanser
Sains Bioperubatan
Diagnostik molekul
Biologi Molekul
PENERBITAN
2024
Exploring the Roles of Mitochondrial-Associated MicroRNAs of Head and Neck Cancer Stem Cells in Drug Resistance and Tumor Recurrence
2024
MicroRNAs and their role in breast cancer metabolism (Review)
2024
Evaluating the roles of microRNAs associated with nonalcoholic fatty liver disease in hepatocellular carcinoma tumorigenesis: a systematic review and network analysis
2024
Forecasting the impact of global warming on soil bacterial communities using simulated systems
2023
Diagnostic Utility of TSSC3 and RB1 Immunohistochemistry in Hydatidiform Mole
2023
Whole genome sequence data of an Antarctic bacterium, Arthrobacter sp. ES1 from the Schirmacher Oasis, East Antarctica
2023
Transcriptomics analysis provides insights into the heat adaptation strategies of an Antarctic bacterium, Cryobacterium sp. SO1
2023
An insight into the associations between microRNA expression and mitochondrial functions in cancer cell and cancer stem cell
2022
Expression Analysis using Reverse Transcription Quantitative Real-Time PCR (RTqPCR) Suggests Different Strategies in Parageobacillus caldoxylosilyticus ER4B under Exposure to Cold Shock
2022
Proteobacteria, Acidobacteria, and Chloroflexi bacteria from Antarctic soils survive under simulated tropical conditions
2021
ASSOCIATION OF DIETARY FATS WITH GUT MICROBIOTA PROFILE: HOW DOES PALM OIL FIT IN?
2021
Genomics and transcriptomics analyses provide insights into the cold adaptation strategies of an Antarctic bacterium, Cryobacterium sp. SO1
2020
Bioinformatics in the Identification of Bacteria
2020
Microbial community diversity in the soil of Barrientos Island estimated by RAPD and Biolog Ecoplate methods
2020
Potential miRNAs for miRNA-Based Therapeutics in Breast Cancer
2020
Genome of a thermophilic bacterium Geobacillus sp. TFV3 from Deception Island, Antarctica
2020
Tumour Growth Inhibition and Systemic Responses of ?sopB?sopD?pipD Disrupted Salmonella Agona and Salmonella Typhimurium in Mice.
2019
Targeted inactivation of Salmonella Agona metabolic genes by group II introns and in vivo assessment of pathogenicity and anti-tumour activity in mouse model
2019
The Interplay between MicroRNAs and Cellular Components of Tumour Microenvironment (TME) on Non-Small-Cell Lung Cancer (NSCLC) Progression
2018
Analysis of bacterial communities of King George and Deception Islands, Antarctica using high-throughput sequencing
2018
Targeted inactivation of Salmonella agona metabolic genes by group II introns and in vivo assessment of pathogenicity and anti-tumour activity in mouse model
2018
Effects of Open-Top Chamber on Soil Chemical Properties and Microbial Growth
2018
Genome sequences of two cold-adapted Cryobacterium spp. SO1 and SO2 from Fildes Peninsula, Antarctica
2018
Bacterial Endophytes: A Reservoir of Bioactive Anti-Microbial Compounds
2017
Small RNA sequencing and differential expression of miRNAs in colorectal cancer
2017
Molecular profiling of genetic alterations in selected non-small cell lung cancer on formalin-fixed paraffin-embedded tissue specimens
2017
Actinobacteria from Greenwich Island and Dee Island: Isolation, diversity and distribution
2017
The roles of miRNAs in human breast cancer and canine mammary tumor
2016
Bis(phosphane)copper(I) and silver(I) dithiocarbamates: crystallography and anti-microbial assay
2016
In vitro antibacterial and time kill evaluation of mononuclear phosphanegold(I) dithiocarbamates
2016
NEW INDOLIZIDINE ALKALOIDS FROM PSYCHROPHILIC YEAST Glyciozyma antarctica PI12
2015
Molecular characterization of Escherichia coli isolated from different food sources
2015
The importance of Au/p(aryl) interactions in the formation of spherical aggregates in binuclear phosphane gold(I) complexes of a bipodal thiocarbamate dianion: a combined crystallographic and computat
2015
Association of Cholesteryl Ester Transfer Protein and Endothelial Nitric Oxide Synthase Gene Polymorphisms With Coronary Artery Disease in the Multi-Ethnic Malaysian Population
2015
miR-205 in Situ Expression and Localization in Head and Neck Tumors - a Tissue Array Study
2015
Isolation, identification and screening of Actinobacteria in volcanic soil of Deception Island (the Antarctic) for antimicrobial metabolites
2015
Phosphanegold (I) thiolates, Ph3PAu [SC (OR)= NC6H4Me-4] for R= Me, Et and iPr, induce apoptosis, cell cycle arrest and inhibit cell invasion of HT-29 colon cancer cells through modulation of the nucl
2015
Synthesis of a DNA-targeting nickel (II) complex with testosterone thiosemicarbazone which exhibits selective cytotoxicity towards human prostate cancer cells (LNCaP)
2015
Molecular mechanisms of apoptosis and cell selectivity of zinc dithiocarbamates functionalized with hydroxyethyl substituents
2015
Three ammonium salts of sulfathiazole: crystallography and anti-microbial assay
2014
Analysis of TP53 gene expression and p53 level of human hypopharyngeal FaDu (HTB-43) head and neck cancer cell line after microRNA-181a inhibition
2013
Detection of epidermal growth factor receptor mutations in formalin fixed paraffin embedded biopsies in Malaysian non-small cell lung cancer patients
2013
Epidermal Growth Factor Receptor Mutations in Lung Adenocarcinoma in Malaysian Patients
2013
Analysis of TP53 gene expression and p53 level of human hypopharyngeal FaDu (HTB-43) head and neck cancer cell Line after microRNA-181a inhibition
2013
miR-181a regulates proliferation, migration and invasion in head and neck cancer
2013
Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(Oalkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
2013
Molecular characterisation of Vibrio parahaemolyticus carrying tdh and trh genes using ERIC-, RAPD- and BOX-PCR on local Malaysia bloody clam and Lala
2013
Phosphanegold(I) dithiocarbamates, R3PAu[SC(=S)N(iPr)CH2CH2OH] for R=Ph, Cy and Et: Role of phosphane-bound R substituents upon in vitro cytotoxicity against MCF-7R breast cancer cells and cell death pathways
2012
Identification of actinomycete communities in Antarctic soil from Barrientos Island using PCR-denaturing gradient gel electrophoresis
2012
p53 codon 72 polymorphisms and random amplified polymorphic DNA analysis of non-melanoma skin cancer through archival formalin-fixed paraffin-embedded tissue
2012
Evaluation of injury to Saccharomyces rouxii YSa40 cells in low water activity/pH glycerol/CPB stress system
2012
Analysis of Antarctic proteobacteria by PCR fingerprinting and screening for antimicrobial secondary metabolites
2012
miR-181a regulates multiple pathways in hypopharyngeal squamous cell carcinoma
2012
Molecular Characterization of Antarctic actinobacteria and screening for antimicrobial metabolite production
2012
Molecular quantitation and characterization of Vibrio cholerae from different seafood obtained from wetmarket and supermarket
2011
Bioprotective properties of three Malaysia Phyllanthus species: An investigation of the antioxidant and antimicrobial activities
2011
Quantitative analysis of Roundup Ready soybean content in soy-derived food and animal feed by using Real-time PCR incorporated with cloned DNA fragments
2011
Differential microRNA expression and identification of putative miRNA targets and pathways in head and neck cancers
2011
The used of recombinant plasmid DNA in GMO quantitative analysis of insect resistance maize targeted unapproved StarLink corn and approved Bt176 corn in food and feed sold commercially sold Malaysia
2011
Development of multiplex-PCR for Genetically Modified Organism (GMO) detection targeting EPSPS and Cry1Ab genes in soy and maize samples
2010
Caenorhabditis elegans-based analysis of Salmonella enterica
2010
Surface plasmon resonance biosensor for real-time detection of genetically modified organisms
2010
Evaluation of DNA and RNA Extraction Methods
2010
Molecular Diversity of Fungal Endophytes Isolated from Garcinia mangostana and Garcinia parvifolia
2009
Molecular characterization and antimicrobial resistance profiling of Salmonella enterica subsp. enterica isolated from ?Selom? (Oenanthe stolonifera)
2009
Virulotyping of Salmonella enterica subsp. enterica isolated from indigenous vegetables and poultry meat in Malaysia using multiplex-PCR
2008
Characterization of multiple-antimicrobial-resistant Salmonella enterica Subsp. enterica isolated from indigenous vegetables and poultry in Malaysia
2008
Comparison of PCR fingerprinting techniques for the discrimination of Salmonella enterica subsp. enterica serovar Weltevreden isolated from indigenous vegetables in Malaysia