PROFILE
UPM's Staff Profile
YBHG. PROFESOR DR. NORHAIZAN BINTI MOHD ESA
PROFESSOR
FACULTY OF MEDICINE AND HEALTH SCIENCES
nhaizan@upm.edu.my
PROFESSIONAL
NAME :
(Ybhg. Profesor Dr.) NORHAIZAN BINTI MOHD ESA
POST :
PROFESSOR
ENTITY :
FACULTY OF MEDICINE AND HEALTH SCIENCES
FIELD OF SUPERVISION
BIOCHEMISTRY / CANCER BIOLOGY AND ONCOLOGY / MEDICAL BIOTECHNOLOGY / NUTRITIONAL SCIENCES / MOLECULAR MEDICINE
PUBLICATION
2025
Optimized Eleutherine bulbosa Urb. bulb extract on the inhibition of 3D retinoblastoma spheroids cultured in type I murine collagen
2024
Manilkara zapota (L.) P. Royen Leaf Mitigates Colitis-Associated Colon Cancer through Anti-inflammatory Modulation in BALB/C Mice
2023
Stingless Bee (Heterotrigona Itama) Honey and Its Phenolic-Rich Extract Ameliorate Oxidant–Antioxidant Balance via KEAP1-NRF2 Signalling Pathway
2023
The Antiproliferative Effect of Chloroform Fraction of Eleutherine bulbosa (Mill.) Urb. on 2D- and 3D-Human Lung Cancer Cells (A549) Model
2023
Rice Bran: From Waste to Nutritious Food Ingredients
2023
LC-MS/MS and GC-MS Analysis for the Identification of Bioactive Metabolites Responsible for the Antioxidant and Antibacterial Activities of Lygodium microphyllum (Cav.) R. Br.
2023
Chemical screening and mosquitocidal activity of essential oil derived from Mikania scandens (L.) Willd. against Anopheles gambiae Giles and their non-toxicity on mosquito predators
2023
Chemotherapeutic potential of matcha green tea (Camellia sinensis) polyphenols to induce cell-cycle arrest and apoptosis in WERI-Rb-1 retinoblastoma cells
2023
Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington's disease-like symptoms in rats: possible antioxidant and anti-inflammatory mechanisms
2023
In Vitro Investigation of Antioxidant and Antidiabetic Properties of Phenolic-Rich Extract from Stingless Bee Honey (Heterotrigona itama)
2022
Caffeic Acid Phenethyl Ester Attenuates Dextran Sulfate Sodium?Induced Ulcerative Colitis Through Modulation of NF??B and Cell Adhesion Molecules
2022
Induction of apoptosis by Eleutherine bulbosa (Mill.) Urb. bulb extracted under optimised extraction condition on human retinoblastoma cancer cells (WERI-Rb-1)
2021
Optimized Green Extraction Conditions of Matcha Green Tea (Camellia Sinensis) using Central Composite Design for Maximal Polyphenol and Antioxidant Contents
2021
Eleutherine bulbosa (Mill.) Urb. Bulb: Review of the Pharmacological Activities and Its Prospects for Application
2020
Heat assisted extraction of phenolic compounds from Eleutherine bulbosa (Mill.) bulb and its bioactive profiles using response surface methodology
2020
Manilkara zapota (L.) P. Royen: Potential Source of Natural Antioxidants
2020
Enhancement of Phenolics and Antioxidant Activity via Heat Assisted Extraction From Moringa oleifera Using Response Surface Methodology and Its Potential Bioactive Constituent
2020
An insight on superoxide dismutase (SOD) from plants for mammalian health enhancement
2020
Oxidative Stress, Diet and Prostate Cancer
2020
Optimized Aqueous Extraction Conditions for Maximal Phenolics, Flavonoids and Antioxidant Capacity from Artocarpus heterophyllus (Jackfruit) Leaves by Response Surface Methodology (RSM)
2019
Manilkara zapota (L.) P. Royen leaf water extract triggered apoptosis and activated caspase-dependent pathway in HT-29 human colorectal cancer cell line
2019
Wound healing potential of edible plants
2019
Acute Oral Evaluation of Phytic Acid-Chitosan-Magnetic Iron Oxide Nanoparticles in Mice
2019
Carotenoids: How Effective Are They to Prevent Age-Related Diseases?
2019
Curcumin combination therapy: The implication and efficacy in cancer
2019
Effect of High-Fat Diets on Oxidative Stress, Cellular Inflammatory Response, and Cognitive Function
2019
Comparison of Sugar Content, Mineral Elements and Antioxidant Properties of Heterotrigona Itama Honey from Suburban and Forest in Malaysia
2018
Pharmacological insights into antioxidants against colorectal cancer: A detailed review of the possible mechanisms
2018
Inositol-6 phosphate inhibits the mTOR pathway and induces autophagy-mediated death in HT-29 colon cancer cells
2018
In Vitro Wound Healing Potential of Stem Extract of Alternanthera sessilis
2018
Anticancer potential of Alternanthera sessilis extract on HT-29 human colon cancer cells
2018
Effects of palm-based high oleic blended cooking oil diet on selected biomarkers of inflammation and obesity compared to extra virgin high olive diet in overweight Malaysian adults
2018
Manilkara zapota L. P Royen leaf water extract induces apoptosis in human hepatocellular carcinoma (HepG2) cells via ERK1/2/Akt1/JNK1 signallng pathways
2018
Amelioration of Oxidative Stress through Apoptosis-Mediated Pathway in Colon Cancer Cells by Hexane Fraction of Moringa oleifera Extract
2018
ROS-Mediated Mitochondrial Pathway is Required for Manilkara Zapota (L.) P. Royen Leaf Methanol Extract Induces Apoptosis in the Modulation of Caspase Activation and EGFR/NF-?B Activities of HeLa Human Cervical Cancer Cells
2018
An Intrinsic Mitochondrial Pathway Is Required for Phytic Acid-Chitosan-Iron Oxide Nanocomposite (Phy-CS-MNP) to Induce G0/G1 Cell Cycle Arrest and Apoptosis in the Human Colorectal Cancer (HT-29) Cell Line
2018
Suppression of Proinflammatory Cytokines and Mediators in LPS-Induced RAW 264.7 Macrophages by Stem Extract of Alternanthera sessilis via the Inhibition of the NF-?B Pathway
2018
Nutrients and Oxidative Stress: Friend or Foe?
2018
Interesterified Palm Olein (IEPalm) and Interesterified Stearic Acid-Rich Fat Blend (IEStear) Have No Adverse Effects on Insulin Resistance: A Randomized Control Trial
2018
Designing of the Anticancer Nanocomposite with Sustained Release Properties by Using Graphene Oxide Nanocarrier with Phenethyl Isothiocyanate as Anticancer Agent
2018
Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases
2017
Molecular Docking Analysis of Phytic Acid and 4-hydroxyisoleucine as Cyclooxygenase-2, Microsomal Prostaglandin E Synthase-2, Tyrosinase, Human Neutrophil Elastase, Matrix Metalloproteinase-2 and -9, Xanthine Oxidase, Squalene Synthase, Nitric Oxide
2017
Molecular docking analysis of Carica papaya Linn constituents as antiviral agent
2017
Scientific evidence-based of rice by-products for cancer prevention: Chemopreventive properties of waste products from rice milling on carcinogenesis in vitro and in vivo
2017
Isolation and characterization of lectin from the Artist’s Conk medicinal mushroom, Ganoderma applanatum (Agaricomycetes) and evaluation of its antiproliferative activity in HT-29 colon cancer cells
2017
Molecular docking analysis of phytic acid and 4-hydroxyisoleucine as COX-2, mPGES-2, Tyrosinase, HNE, MMP-2 & 9, XO, SQS, NOS, HAR and LOX inhibitors
2017
Sustained release of anticancer agent phytic acid from its chitosan-coated magnetic nanoparticles for drug delivery system
2016
The inhibitory activity of cocoa phenolic extract against pro-inflammatory mediators secretion induced by lipopolysaccharide in RAW 264.7 cells
2016
Anti-Cancer Activity of Three Terminalia Species and Preliminary Phytochemical Screening
2016
Brewers? rice, a by-product from rice processing, has antiproliferative activity on human colorectal cancer (HT-29) cell line
2016
Brewers' rice attenuated aberrant crypt foci developing in colon of azoxymethane-treated rats
2016
Sustained Release of Anticancer Agent Phytic Acid from Its Chitosan-Coated Magnetic Nanoparticles for Drug Delivery System
2016
Boldine suppresses dextran sulfate sodium-induced mouse experimental colitis: NF-κB and IL-6/STAT3 as potential targets
2015
Inhibition of prostaglandin E2 (PGE2) and 5-lipooxgenase (5-LOX) by cocoa phenolic extract treatment
2015
Gallic acid suppresses inflammation in dextran sodium sulfate-induced colitis in mice: Possible mechanisms
2015
Water extract of brewers? rice induces apoptosis in human colorectal cancer cells via activation of caspase 3 and 8 and downregulates the Wnt/beta-catenin
2015
Dietary cocoa inhibits colitis-associated cancer: A crucial involvement of the IL-6/STAT3 pathway
2015
Allicin alleviates dextran sodium sulfate (DSS)-induced ulcerative colitis in BALB/c mice
2015
Dietary cocoa protects against colitisassociated cancer by activating the Nrf2/Keap1 pathway
2015
Brewers's rice modulates oxidative stress in azoxymethane-mediated colon carcinogenesis in rats
2015
Gallic acid attenuates dextran sulfate sodium- induced experimental colitis in BALB/c mice
2015
Identification of phenolic compounds in polyphenols-rich extract of Malaysian cocoa powder using the HPLC-UV-ESI?MS/MS and probing their antioxidant properties
2015
Water extract of brewers? rice induces antiproliferation of human colorectal cancer (HT-29) cell lines via the induction of apoptosis
2015
Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats
2014
Water Extract of Brewers' Rice Induce Antiproliferation of Human Colorectal Cancer (HT-29) Cell Lines via the Induction of Apoptosis
2014
Brewers' rice induces apoptosis in azoxymethane-induced colon carcinogenesis in rats via suppression of cell proliferation and the Wnt signaling pathway
2014
Luteolin, a bioflavonoid inhibits colorectal cancer through modulation of multiple signaling pathways: A Review
2014
Signal Transducer and Activator of Transcription 3 - A Promising Target in Colitis-Associated Cancer
2014
Effects of gamma oryzanol supplementation on anthropometric measurements & muscular strength in healthy males following chronic resistance training
2013
Preventive inositol hexaphosphate (IP6) extracted from rice bran inhibits colorectal cancer through involvement of Wnt/β-catenin and COX-2 pathway
2013
Antioxidant properties and antiproliferative effect of brewers? rice extract (temukut) on selected cancer cell lines
2013
Pro-Apoptotic Effect of Rice Bran Inositol Hexaphosphate (IP6) on HT-29 Colorectal Cancer Cells
2013
By-products of rice processing: An overview of health benefits and applications
2013
The Protective Effect of Cocoa (Theobroma cacao L.) in Colon Cancer
2013
Palm oil: Features and applications
2013
Suppression of B-catenin and Cyclooxygenase-2 Expression and Cell Proliferation in Azoxymethane-Induced Colonic Cancer in Rats by Rice Bran Phytic Acid (IP6)
2013
Antioxidant activity of white rice, brown rice and germinated brown rice (in vivo and in vitro) and the effects on lipid peroxidation and liver enzymes in hyperlipidaemic rabbits
2013
Dietary non-nutritive factors on molecular targets of colorectal cancer: An update
2013
Evaluation of acute, subacute and subchronic oral toxicity of Rhaphidophora decursiva (Roxb.) Schott extract in male Sprague Dawley rats
2013
The trans fatty acid content in human milk and its association with maternal diet among lactating mothers in Malaysia
2013
The Trans Fatty Acids Content of Selected Foods in Malaysia
2013
Preventive Inositol Hexaphosphate extracted from Rice Bran Inhibits Colorectal cancer through Involvment of Wnt/beta-catenin and COX-2 Pathways
2012
Effects of gamma oryzanol supplementation on anabolic and catabolic status after acute and chronic resistance exercise
2012
The trans fatty acid content in human milk and its association with maternal diet among lactating mothers in Malaysia
2011
Antioxidant and Cytotoxicity Effect of Rice Bran Phytic Acid as an Anticancer Agent on Ovarian, Breast and Liver Cancer Cell Lines
2011
Improving the Lipid Profile in Hypercholesterolemia-Induced Rabbit by Supplementation of Germinated Brown Rice
2010
Antioxidant activity in different parts of roselle (Hibiscus sabdariffa L.) extracts and potential exploitation of the seeds
2010
Rice bran phytic acid induces growth inhibition, cell cycle arrest and apoptosis on human colorectal adenocarcinoma cells
2010
Anticarcinogenic afficacy of phytic acid extracted from rice bran on azoxymethane-induced colon carcinogenesis in rats
2009
Determination of Phytate, Iron, Zinc, Calcium Contents and Their Molar Ratios in Commonly Consumed Raw and Prepared Food in Malaysia