A
PROFILE
UPM's Staff Profile
YBHG. PROFESOR DR. LATIFAH BINTI SAIFUL YAZAN
PROFESSOR
FACULTY OF MEDICINE AND HEALTH SCIENCES
latifahsy@upm.edu.my
UPM WEBSITE
PROFILE
latifahsy
BM
EN

PROFESSIONAL

NAME :
(Ybhg. Profesor Dr.) LATIFAH BINTI SAIFUL YAZAN
POST :
PROFESSOR
ENTITY :
FACULTY OF MEDICINE AND HEALTH SCIENCES

FIELD OF SUPERVISION
BIOTHERAPEUTICS / CANCER BIOLOGY AND ONCOLOGY / CELL BIOTECHNOLOGY / MEDICAL BIOTECHNOLOGY / MOLECULAR BIOTECHNOLOGY
EDUCATION
PHD
UNIVERSITI PUTRA MALAYSIA, SERDANG, SELANGOR
Graduated : 2003
BACELOR SAINS (BIOTEKNOLOGI)
UNIVERSITI PERTANIAN MALAYSIA, SERDANG, SELANGOR
Graduated : 1995
DIPLOMA PENTERJEMAHAN AWAM (CEMERLANG)
INSTITUT TERJEMAHAN NEGARA MALAYSIA
Graduated : 1998
BOOK PUBLICATION
1. Scientific Evidence: Malaysian Medicinal Plants with Wound Healing Properties
    ISPN: 9789672989073
JOURNAL PUBLICATION
1. Dillenia species: A review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
2. Cytotoxicity of thymoquinone and thymoquinone-loaded nanostructured lipid carriers on breast cancer cells (MDA-MB-231 and MCF-7)
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
3. Cytotoxicity of Thymoquinone (TQ) from Nigella Sativa Towards human Cervical Carcinoma Cells (Hela)
    Journal type: Other Abstracting / Indexing Bodies
4. Kenaf seed oil from supercritical carbon dioxide fluid extraction induced G1 phase cell cycle arrest and apoptosis in leukemia cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
5. Thmoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with downregulation of Bcl-2 protein
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
6. Induction of apoptosis through oxidative stress-related pathways in MCF-7, human breast cancer cells, by ethyl acetate extract of Dillenia suffruticosa.
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
7. Chemopreventive properties and toxicity of kelulut honey in Sprague Dawley rats induced with azoxymethane
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
8. Nordamnacanthal induced apoptosis and mitotic-G2/M arrest with downregulation of Bcl-2 in the human breast cancer cell line (MCF-7)
    Journal type: Non Citation-Indexed
9. The improvement of in vivo model (balb/c mice) for cervical carcinogenesis using diethylstilbestrol (DES)
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
10. Acute and sub-acute toxicity profile of thymoquinone-loaded nanostructured lipid carrier (TQNLC) in BALB/c mice
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
11. Induction of apoptosis and G2/M arrest by ampelopsin E from Dryobalanops towards triple negative breast cancer cells, MDA-MB-231
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
12. Phenolics-saponins rich fraction of defatted kenaf seed meal exhibits cytotoxicity towards cancer cell lines
    Journal type: Citation-Indexed - Scopus
13. Germinated brown rice (GBR) reduces the incidence of aberrant crypt foci with the involvement of beta-catenin and COX-2 in azoxymethane-induced colon cancer in rats (2010)
    Journal type: Citation-Indexed - Scopus
14. Bcl-2 was downregulated in G2/M-arrest breast cancer cells MCF-7 -treated with nordamnacanthal
    Journal type: Citation-Indexed - Scopus
15. Effect of kenaf seed oil from different ways of extraction towards ovarian cancer cells.
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
16. Anti breast cancer properties and toxicity of Dillenia suffruticosa root aqueous extract in BALB/c mice
    Journal type: Citation-Indexed - Scopus
17. Betulinic acid was more cytotoxic towards the human breast cancer cell line MDA-MB-231 than the human promyelocytic leukaemia cell line HL-60
    Journal type: Non Citation-Indexed
18. Kenaf seed oil from supercritical carbon dioxide fluid extraction shows cytotoxic effects towards various cancer cell lines
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
19. Potential implications of GRP58 expression and susceptibility of cervical cancer to cisplatin and thymoquinone-based therapy
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
20. Induction of cell cycle arrest and apoptosis by betulinic acid-rich fraction by Dillenia suffruticosa root in MCF-7 cells involved p53/p21 and mitochondrial signalling pathway
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
21. Dillenia suffruticosa dichloromethane root extract induced apoptosis towards MDA-MB-231 triple negative breast cancer cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
22. Dillenia suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
23. Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
24. A review on current nanomaterials and their drug conjugate for targeted breast cancer treatment.
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
25. Kenaf seed oil from supercritical carbon dioxide fluid extraction inhibits the proliferation of WEHI-3B leukemia cells in vivo
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
26. Induction of cell cycle arrest and apoptosis in MCF-7 cells by Dillenia suffruticosa root extract via reactive oxygen species formation and multiple signaling pathways
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
27. Thymoquinone-loaded nanostructured lipid carrier exhibited cytotoxicity towards breast cancer cell lines (MDA-MB-231 and MCF-7) and cervical cancer cell lines (HeLa and SiHa)
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
28. Antiulcer properties of kelulut honey against ethanol-induced gastric ulcer
    Journal type: Citation-Indexed - Scopus
29. Effects of Kelulut honey from Trigona sp. on zebrafish (Danio rerio) embryo that mimics human embryonic development
    Journal type: Non Citation-Indexed
30. Ampelopsin E Reduces the Invasiveness of the Triple Negative Breast Cancer Cell Line, MDA-MB-231.
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
31. Dillenia suffruticosa dichloromethane root extract reduced metastasis of 4T1 cells to the liver and heart without causing toxicity in female BALB/c mice
    Journal type: Citation-Indexed - Scopus
32. Acute Toxicity Study of Intravenous Administration of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) in Sprague Dawley Rats
    Journal type: Citation-Indexed - Scopus
33. Induction of cell cycle arrest and apoptosis by copper complex Cu(SBCM)₂ towards oestrogen-receptor positive MCF-7 breast cancer cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
34. Proteinaceous postbiotic metabolite produced by Lactobacillus plantarum I-UL4 exhibits anti-colorectal cancer and immunomodulatory properties in azoxymethane-induced rats
    Journal type: Citation-Indexed - Scopus
35. Radioprotective effects of kelulut honey in zebrafish model
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
36. Anticancer potential of damnacanthal and nordamnacanthal from Morinda elliptica roots on T-lymphoblastic leukemia cells
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
37. Association of temperature and rainfall with Aedes mosquito population in 17th College of Universiti Putra Malaysia
    Journal type: Citation-Indexed - Scopus
38. Ultrastructural and morphological effects in T-lymphoblastic leukemia CEM-SS cells following treatment with nordamnacanthal and damnacanthal from roots of Morinda elliptica
    Journal type: Citation-Indexed Journal - Science Citation Index (JCR)
39. Aedestech Mosquito Home System Prevents the Hatch of Aedes Mosquito Eggs and Reduces its Population
    Journal type: Citation-Indexed - Scopus
PUBLICATION
2024
Mechanism of damnacanthal induced apoptosis in CEM-SS cell line
2022
Ultrastructural and morphological effects in T-lymphoblastic leukemia CEM-SS cells following treatment with nordamnacanthal and damnacanthal from roots of Morinda elliptica
2021
Proteinaceous postbiotic metabolite produced by Lactobacillus plantarum I-UL4 exhibits anti-colorectal cancer and immunomodulatory properties in azoxymethane-induced rats
2021
Association of temperature and rainfall with Aedes mosquito population in 17th College of Universiti Putra Malaysia
2021
Ultrastructural and Morphological Effects in T-Lymphoblastic Leukaemia, CEM-SS Cells following treatment with Nordamnacanthal and Damnacanthal from Roots of Morinda elliptica
2021
Radioprotective effects of kelulut honey in zebrafish model
2021
Anticancer potential of damnacanthal and nordamnacanthal from Morinda elliptica roots on T-lymphoblastic leukemia cells
2020
Anticancer Activity Of Christia Vespertilionis Root And Leaf Extracts And Fractions Against Breast Cancer Cell Lines
2020
Pharmacokinetics and biodistribution of thymoquinone-loaded nanostructured lipid carrier after oral and intravenous administration into rats
2020
Aedestech Mosquito Home System Prevents the Hatch of Aedes Mosquito Eggs and Reduces its Population
2019
Dillenia suffruticosa dichloromethane root extract reduced metastasis of 4T1 cells to the liver and heart without causing toxicity in female BALB/c mice
2019
Induction of cell cycle arrest and apoptosis by copper complex Cu(SBCM)? towards oestrogen-receptor positive MCF-7 breast cancer cells
2019
Acute Toxicity Study of Intravenous Administration of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) in Sprague Dawley Rats
2019
Ampelopsin E Reduces the Invasiveness of the Triple Negative Breast Cancer Cell Line, MDA-MB-231.
2018
Thymoquinone loaded in nanostructured lipid carrier showed enhanced anti-cancer activity in 4T1-tumor bearing mice
2018
Antiulcer properties of kelulut honey against ethanol-induced gastric ulcer
2017
A review on current nanomaterials and their drug conjugate for targeted breast cancer treatment.
2016
Induction of apoptosis and G2/M arrest by ampelopsin E from Dryobalanops towards triple negative breast cancer cells, MDA-MB-231
2016
Chemopreventive properties and toxicity of kelulut honey in Sprague Dawley rats induced with azoxymethane
2016
Dillenia suffruticosa dichloromethane root extract induced apoptosis towards MDA-MB-231 triple negative breast cancer cells
2016
Acute and sub-acute toxicity profile of thymoquinone-loaded nanostructured lipid carrier (TQNLC) in BALB/c mice
2015
Anti breast cancer properties and toxicity of Dillenia suffruticosa root aqueous extract in BALB/c mice
2015
Induction of apoptosis in MCF-7 cells via oxidative stress generation, mitochondria-dependent and caspase-independent pathway by ethyl acetate extract of Dillenia suffruticosa, and its chemical profil
2015
Induction of cell cycle arrest and apoptosis by betulinic acid-rich fraction by Dillenia suffruticosa root in MCF-7 cells involved p53/p21 and mitochondrial signalling pathway
2015
Thymoquinone-loaded nanostructured lipid carrier exhibited cytotoxicity towards breast cancer cell lines (MDA-MB-231 and MCF-7) and cervical cancer cell lines (HeLa and SiHa)
2014
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways
2014
Dillenia species: A review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
2014
Induction of apoptosis through oxidative stress-related pathways in MCF-7, human breast cancer cells, by ethyl acetate extract of Dillenia suffruticosa.
2014
Potential implications of GRP58 expression and susceptibility of cervical cancer to cisplatin and thymoquinone-based therapy
2013
The improvement of in vivo model (balb/c mice) for cervical carcinogenesis using diethylstilbestrol (DES)
2013
Dillenia species: A review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
2013
Dillenia suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis
2013
Acute and subacute oral toxicity of dillenia suffruticosa root aqueous extract in balb/c mice
2012
Kenaf seed oil from supercritical carbon dioxide fluid extraction inhibits the proliferation of WEHI-3B leukemia cells in vivo
2011
Kenaf seed oil from supercritical carbon dioxide fluid extraction induced G1 phase cell cycle arrest and apoptosis in leukemia cells
2011
Thmoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with downregulation of Bcl-2 protein
2011
Kenaf seed oil from supercritical carbon dioxide fluid extraction shows cytotoxic effects towards various cancer cell lines
2011
Effect of kenaf seed oil from different ways of extraction towards ovarian cancer cells.
2010
Germinated brown rice (GBR) reduces the incidence of aberrant crypt foci with the involvement of beta-catenin and COX-2 in azoxymethane-induced colon cancer in rats (2010)
2010
Kenaf seed oil from supercritical carbon dioxide fluid extraction induced G1 cell cycle arrest and apoptosis in leukemia cells
2010
Kenaf seed oil inhibits the proliferation of WEHI-3B leukemia cells in vivo
2010
Bcl-2 was downregulated in G2/M-arrest breast cancer cells MCF-7 -treated with nordamnacanthal
2009
Cytotoxicity of Thymoquinone (TQ) from Nigella Sativa Towards human Cervical Carcinoma Cells (Hela)